Immunohistochemical Method and Histopathology Judging for the Systemic Synuclein Sampling Study (S4)
Beach T, Serrano G, Kremer T, Canamero M, Dziadek S, Sade H, Derkinderen P, Corbillé A, Letournel F, Munoz D, White C, Schneider J, Crary J, Sue L, Adler C, Glass M, Intorcia A, Walker J, Foroud T, Coffey C, Ecklund D, Riss H, Goßmann J, König F, Kopil C, Arnedo V, Riley L, Linder C, Dave K, Jennings D, Seibyl J, Mollenhauer B, Chahine L, Guilmette L, Russell D, Noyes-Lloyd C, Mitchell C, Smith D, Potter M, Case R, Lott D, Duffy A, Hogarth P, Cresswell M, Akhtar R, Purri R, Amara A, Blair C, Keshavarzian A, Marras C, Visanji N, Rothberg B, Oza V. Immunohistochemical Method and Histopathology Judging for the Systemic Synuclein Sampling Study (S4). Journal Of Neuropathology & Experimental Neurology 2018, 77: 793-802. PMID: 30107604, PMCID: PMC6097838, DOI: 10.1093/jnen/nly056.Peer-Reviewed Original ResearchConceptsParkinson's diseaseASyn pathologyΑ-synuclein pathologySubmandibular gland biopsyPeripheral biopsiesControl subjectsGland biopsyBlinded panelImmunohistochemical methodsImmunoperoxidase methodMonoclonal antibodiesScore agreementNeuropathologistsPathologyBiopsySkinSubsequent testingSampling study
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