2025
Comparison of Outcomes Between Low-Risk Aortic Valve Replacement Trials and a Surgical Registry
Mori M, Shioda K, Waldron C, Huang C, Gaudino M, George I, Takayama H, Geirsson A. Comparison of Outcomes Between Low-Risk Aortic Valve Replacement Trials and a Surgical Registry. JAMA Network Open 2025, 8: e2453267. PMID: 39761046, PMCID: PMC11704974, DOI: 10.1001/jamanetworkopen.2024.53267.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementLow-risk trialsSTS ACSDLow riskSociety of Thoracic Surgeons Adult Cardiac Surgery DatabaseSAVR armPARTNER 3Evolut Low Risk trialAdult Cardiac Surgery DatabaseCompare 30-day mortalityConcomitant cardiac operationsCardiac Surgery DatabaseLow surgical riskMortality rateAortic valve replacementSevere aortic stenosisStroke rateIncidence of patientsTrial exclusion criteriaRisk of mortalitySAVR cohortCross-sectional studyComparison of outcomesIncidence of strokeNontrial setting
2020
Comparative utility of frailty to a general prognostic score in identifying patients at risk for poor outcomes after aortic valve replacement
Shi S, Festa N, Afilalo J, Popma JJ, Khabbaz KR, Laham RJ, Guibone K, Kim DH. Comparative utility of frailty to a general prognostic score in identifying patients at risk for poor outcomes after aortic valve replacement. BMC Geriatrics 2020, 20: 38. PMID: 32013890, PMCID: PMC6998298, DOI: 10.1186/s12877-020-1440-4.Peer-Reviewed Original ResearchConceptsAortic valve replacementTranscatheter aortic valve replacementFrailty indexLee indexPoor outcomeValve replacementSAVR cohortTAVR cohortC-statisticFunctional declineSevere symptomsDeficit-accumulation frailty indexSingle academic medical centerProspective cohort studyHighest c-statisticAcademic medical centerBackgroundCurrent guidelinesSAVR patientsTAVR patientsCohort studyGeriatric assessmentOverall cohortPrognostic scoreMedical CenterCohort
2018
Trends in volume and risk profiles of patients undergoing isolated surgical and transcatheter aortic valve replacement
Mori M, Bin Mahmood SU, Geirsson A, Yun JJ, Cleman MW, Forrest JK, Mangi AA. Trends in volume and risk profiles of patients undergoing isolated surgical and transcatheter aortic valve replacement. Catheterization And Cardiovascular Interventions 2018, 93: e337-e342. PMID: 30269424, DOI: 10.1002/ccd.27855.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAgedAged, 80 and overAortic ValveFemaleHeart Valve Prosthesis ImplantationHospitals, High-VolumeHumansMalePatient Reported Outcome MeasuresPractice Patterns, Physicians'Retrospective StudiesRisk AssessmentRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeConceptsSurgical aortic valve replacementAortic valve replacementSTS-PROMSAVR volumeSAVR cohortValve replacementCase volumeTranscatheter aortic valve replacementRisk profileTranscatheter aortic valve replacement (TAVR) programHigh-volume academic medical centerRisk categoriesStudy periodContemporary temporal trendsMedian STS PROMProportion of patientsRisk of mortalityLow-risk categoryAcademic medical centerPROM patientsTAVR cohortTAVR volumeTAVR patientsConsecutive patientsIntermediate risk
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