2025
780-P: Comparative Risk of Adverse Pancreatic Events with Second-Line Glucose-Lowering Therapies in Adults with Type 2 Diabetes at Moderate Cardiovascular Disease Risk
KALATHIYA U, HERRIN J, SINDHU SWARNA K, NEUMILLER J, GALINDO R, UMPIERREZ G, ROSS J, DENG Y, POLLEY E, MICKELSON M, MCCOY R. 780-P: Comparative Risk of Adverse Pancreatic Events with Second-Line Glucose-Lowering Therapies in Adults with Type 2 Diabetes at Moderate Cardiovascular Disease Risk. Diabetes 2025, 74 DOI: 10.2337/db25-780-p.Peer-Reviewed Original ResearchSodium-glucose cotransporter 2 inhibitorsGLP-1RAAcute pancreatitisPancreatic cancerType 2 diabetesRisk of pancreatic cancerIncident acute pancreatitisMedicare fee-for-servicePancreatitis eventsComparative riskAssociated with lower riskFee-for-serviceCardiovascular disease riskGlucagon-like peptide-1 receptor agonistsModerate cardiovascular disease riskSecond-line glucose-lowering therapyAssociated with increased riskAssociated with higher riskRisk of acute pancreatitisPeptide-1 receptor agonistsPropensity score inverse probabilityDipeptidyl peptidase-4 inhibitorsOptumLabs Data WarehouseGLP-1RA therapyModerate cardiovascular risk
2023
Current and Emerging Therapies for Atherosclerotic Cardiovascular Disease Risk Reduction in Hypertriglyceridemia
Mszar R, Bart S, Sakers A, Soffer D, Karalis D. Current and Emerging Therapies for Atherosclerotic Cardiovascular Disease Risk Reduction in Hypertriglyceridemia. Journal Of Clinical Medicine 2023, 12: 1382. PMID: 36835917, PMCID: PMC9962307, DOI: 10.3390/jcm12041382.Peer-Reviewed Original ResearchAtherosclerotic cardiovascular diseaseAtherosclerotic cardiovascular disease risk reductionRisk of atherosclerotic cardiovascular diseasePotential secondary causesBurden of cardiometabolic diseasesLifestyle-based interventionsCardiovascular disease risk reductionHealth care servicesHealth policy strategiesCardiometabolic risk factorsAtherosclerotic cardiovascular disease riskRisk factorsRisk-enhancing factorsRisk reductionDisease risk reductionRisk of acute pancreatitisLipid-lowering medicationsMild-to-moderate hypertriglyceridemiaNutritious food optionsCare servicesFood optionsCardiometabolic diseasesLifestyle modificationMedical conditionsPublic health
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