2015
Dietary salt regulates epithelial sodium channels in rat endothelial cells: adaptation of vasculature to salt
Liu H, Zhang J, Sun Y, Li X, Jiang S, Liu M, Shi J, Song B, Zhao D, Ma H, Zhang Z. Dietary salt regulates epithelial sodium channels in rat endothelial cells: adaptation of vasculature to salt. British Journal Of Pharmacology 2015, 172: 5634-5646. PMID: 25953733, PMCID: PMC4667865, DOI: 10.1111/bph.13185.Peer-Reviewed Original ResearchConceptsEndothelium-dependent relaxationWeeks of HS dietEpithelial sodium channelMesenteric arteryENaC activityEndothelial ENaCEndothelial cellsHS dietSprague-DawleyEnhancement of endothelium-dependent relaxationSodium channelsSecond-order mesenteric arteriesBlocker of ENaCWire myograph assayPatch-clamp techniquePlasma aldosterone levelsSalt-sensitive hypertensionResponse to AChNegative modulatorRat endothelial cellsModulation of vasodilationVascular endothelial cellsFunctional ENaCENaC expressionRelease of NO
1999
The α9 Nicotinic Acetylcholine Receptor Shares Pharmacological Properties with Type A γ-Aminobutyric Acid, Glycine, and Type 3 Serotonin Receptors
Rothlin C, Katz E, Verbitsky M, Elgoyhen A. The α9 Nicotinic Acetylcholine Receptor Shares Pharmacological Properties with Type A γ-Aminobutyric Acid, Glycine, and Type 3 Serotonin Receptors. Molecular Pharmacology 1999, 55: 248-254. DOI: 10.1016/s0026-895x(24)12021-4.Peer-Reviewed Original ResearchACh-evoked currentsType 3 serotonin receptorPharmacological propertiesReceptor antagonist bicucullineGlycinergic antagonist strychnineResponse to AChCochlear outer hair cellsG-aminobutyric acidXenopus laevis oocytesConcentration-dependent mannerAntagonist bicucullineAntagonist strychnineAgonist maximal responseOuter hair cellsFamily of receptorsNicotinic acetylcholine receptorsCholinergic receptorsMaximal responseCys-loop receptorsCys-loop familyCys-loop family of receptorsReceptorsAcetylcholine receptorsHair cellsAcetylcholine
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