2022
Alterations in high‐dimensional T‐cell profile and gene signature of immune aging in HIV‐infected older adults without viremia
Shin MS, Park H, Salahuddin S, Montgomery RR, Emu B, Shaw AC, Kang I. Alterations in high‐dimensional T‐cell profile and gene signature of immune aging in HIV‐infected older adults without viremia. Aging Cell 2022, 21: e13702. PMID: 36036630, PMCID: PMC9577958, DOI: 10.1111/acel.13702.Peer-Reviewed Original ResearchConceptsOlder human immunodeficiency virusPeripheral blood mononuclear cellsHuman immunodeficiency virusAntiretroviral therapyT cellsDetectable viremiaMemory CD8HIV infectionAge-associated immune alterationsYoung human immunodeficiency virusReplication-competent HIV-1Combination antiretroviral therapyEffector memory CD8T-cell countsSubset of CD4T cell profileBlood mononuclear cellsAgeing-associated genesEM CD8Immune alterationsMemory CD4Immune agingImmunodeficiency virusInflammatory moleculesMononuclear cells
2006
Isolation and Characterization of Replication-Competent Human Immunodeficiency Virus Type 1 from a Subset of Elite Suppressors
Blankson J, Bailey J, Thayil S, Yang H, Lassen K, Lai J, Gandhi S, Siliciano J, Williams T, Siliciano R. Isolation and Characterization of Replication-Competent Human Immunodeficiency Virus Type 1 from a Subset of Elite Suppressors. Journal Of Virology 2006, 81: 2508-2518. PMID: 17151109, PMCID: PMC1865922, DOI: 10.1128/jvi.02165-06.Peer-Reviewed Original ResearchConceptsReplication-competent HIV-1Human immunodeficiency virus type 1Immunodeficiency virus type 1Elite suppressorsVirus type 1HIV-1Replication-Competent Human Immunodeficiency Virus Type 1Untreated human immunodeficiency virus type 1Type 1Active antiretroviral therapyUndetectable viral loadReplication-competent virusAntiretroviral therapyImmunologic controlViral loadCoculture assaysPatientsDefective virusCurrent assaysFull-length sequencingVirusIsolatesAssaysPhenotypic analysisViremia
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