CREATE: cell-type-specific cis-regulatory element identification via discrete embedding
Cui X, Yin Q, Gao Z, Li Z, Chen X, Lv H, Chen S, Liu Q, Zeng W, Jiang R. CREATE: cell-type-specific cis-regulatory element identification via discrete embedding. Nature Communications 2025, 16: 4607. PMID: 40382355, PMCID: PMC12085597, DOI: 10.1038/s41467-025-59780-5.Peer-Reviewed Original ResearchConceptsCis-regulatory elementsPrediction of cis-regulatory elementsCell-type-specific cis-regulatory elementsChromatin interaction dataGene regulatory landscapeCell type-specific functionsGene regulatory mechanismsComplex biological traitsLarge-scale predictionGenome sequenceChromatin accessibilitySequence-basedBiological traitsRegulatory codeRegulatory dynamicsRegulatory mechanismsCell typesRegulatory landscapeInteraction dataChromatinGenesIdentificationSequenceSilencingTraits
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