Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsDennis G Moledina, MD, PhD, FASN
Associate Professor AdjunctDownloadHi-Res Photo
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Titles
Associate Professor Adjunct
Director, Research Fellowship, Nephrology; Vice Chief for Research (Clinical and translational), Nephrology; Director, Kidney BioBank, Nephrology
Biography
Dr. Dennis Moledina, MD PhD FASN is physician-scientist with board-certification in Internal Medicine with sub-specialization in Nephrology. He is an associate professor in the department of internal medicine (section of nephrology) at the Yale School of Medicine. He provides attending physician services at the Yale-New Haven Hospital in both nephrology and internal medicine. He completed clinical and post-doctoral fellowships in nephrology at Yale and earned his PhD in investigative medicine from the Yale Graduate School of Arts and Sciences. He has independent research funding from the NIH to develop diagnostic testing and tools for various subtypes of acute kidney injury, particularly for diagnosis of acute interstitial nephritis. Additionally, he is a coinvestigator in NIH-funded multicenter consortia including Kidney Precision Medicine Program (KPMP) and Care of outpatients with acute kidney injury (COPE-AKI). Dr. Moledina directs the Yale Kidney BioBank which is a biorepository that has collected samples from over 1400 participants with kidney biopsy confirmed diagnoses since 2015. Dr. Moledina also serves as the director of the nephrology research fellowship program and vice chief of clinical and translational research.
Last Updated on September 14, 2025.
Appointments
Nephrology
Associate Professor AdjunctPrimary
Other Departments & Organizations
- Cancer Immunology
- Clinical and Translational Research Accelerator (CTRA)
- Colton Center for Autoimmunity
- Internal Medicine
- Nephrology
- Yale Cancer Center
- Yale New Haven Health System
Education & Training
- PhD
- Yale Graduate School of Arts and Sciences, Investigative Medicine (2018)
- Postdoctoral Fellow
- Yale School of Medicine (2018)
- Clinical Fellow
- Yale School of Medicine (2015)
- Resident Physician
- NYU Grossman Long Island School of Medicine (2013)
- MD
- M.P. Shah Medical College (2009)
Advanced Training & Certifications
- FY2026 Yale School of Medicine Healthcare Leadership Program
- Yale School of Medicine (2026)
- Research Program Leadership and Management Skills Course
- Yale School of Medicine (2023)
Research
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Overview
Medical Research Interests
Acute Kidney Injury; Biomarkers; Biopsy, Needle; Kidney; Kidney Diseases; Nephritis, Interstitial; Nephrology; Translational Research, Biomedical
ORCID
0000-0002-9537-9038
Research at a Glance
Yale Co-Authors
Frequent collaborators of Dennis G Moledina's published research.
Publications Timeline
A big-picture view of Dennis G Moledina's research output by year.
Research Interests
Research topics Dennis G Moledina is interested in exploring.
F. Perry Wilson, MD, MSCE
Sherry Mansour, MD, MS, DO
Chirag Parikh, MD, PhD, FACP
Jeffrey Testani, MD, MTR
Mark Perazella, MD
Lloyd G. Cantley, MD
94Publications
3,685Citations
Acute Kidney Injury
Biomarkers
Kidney
Nephritis, Interstitial
Kidney Diseases
Nephrology
Publications
Featured Publications
Identification and validation of urinary CXCL9 as a biomarker for diagnosis of acute interstitial nephritis
Moledina DG, Obeid W, Smith R, Rosales I, Sise M, Moeckel G, Kuperman M, Campbell K, Lefferts S, Meliambro K, Bitzer M, Perazella M, Luciano R, Pober J, Cantley L, Colvin R, Wilson F, Parikh C. Identification and validation of urinary CXCL9 as a biomarker for diagnosis of acute interstitial nephritis. Journal Of Clinical Investigation 2023, 133: e168950. PMID: 37395276, PMCID: PMC10313360, DOI: 10.1172/jci168950.Peer-Reviewed Original ResearchCitationsAltmetricUrine TNF-α and IL-9 for clinical diagnosis of acute interstitial nephritis
Moledina DG, Wilson FP, Pober JS, Perazella MA, Singh N, Luciano RL, Obeid W, Lin H, Kuperman M, Moeckel GW, Cantley LG, Parikh CR. Urine TNF-α and IL-9 for clinical diagnosis of acute interstitial nephritis. JCI Insight 2019, 4: e127456. PMID: 31092735, PMCID: PMC6542610, DOI: 10.1172/jci.insight.127456.Peer-Reviewed Original ResearchCitationsAltmetricDevelopment and external validation of a diagnostic model for biopsy-proven acute interstitial nephritis using electronic health record data
Moledina DG, Eadon MT, Calderon F, Yamamoto Y, Shaw M, Perazella MA, Simonov M, Luciano R, Schwantes-An TH, Moeckel G, Kuperman M, Obeid W, Cantley LG, Parikh CR, Wilson FP. Development and external validation of a diagnostic model for biopsy-proven acute interstitial nephritis using electronic health record data. Nephrology Dialysis Transplantation 2021, 37: 2214-2222. PMID: 34865148, PMCID: PMC9755995, DOI: 10.1093/ndt/gfab346.Peer-Reviewed Original ResearchCitationsAltmetricMortality after acute kidney injury and acute interstitial nephritis in patients prescribed immune checkpoint inhibitor therapy
Baker ML, Yamamoto Y, Perazella MA, Shirali AC, Weinstein J, Simonov M, Testani JM, Kluger HM, Cantley LG, Parikh CR, Wilson FP, Moledina DG. Mortality after acute kidney injury and acute interstitial nephritis in patients prescribed immune checkpoint inhibitor therapy. Journal For ImmunoTherapy Of Cancer 2022, 10: e004421. PMID: 35354588, PMCID: PMC8968986, DOI: 10.1136/jitc-2021-004421.Peer-Reviewed Original ResearchCitationsAltmetricUrine interleukin-9 and tumor necrosis factor-α for prognosis of human acute interstitial nephritis
Moledina DG, Wilson FP, Kukova L, Obeid W, Luciano R, Kuperman M, Moeckel GW, Perazella MA, Cantley LG, Parikh CR. Urine interleukin-9 and tumor necrosis factor-α for prognosis of human acute interstitial nephritis. Nephrology Dialysis Transplantation 2020, 36: 1851-1858. PMID: 33125471, PMCID: PMC8476079, DOI: 10.1093/ndt/gfaa169.Peer-Reviewed Original ResearchCitationsAltmetricThe Association of COVID-19 With Acute Kidney Injury Independent of Severity of Illness: A Multicenter Cohort Study
Moledina DG, Simonov M, Yamamoto Y, Alausa J, Arora T, Cantley LG, Ghazi L, Greenberg JH, Hinchcliff M, Huang C, Mansour SG, Martin M, Peixoto A, Schulz W, Subair L, Testani JM, Young P, Wilson FP. The Association of COVID-19 With Acute Kidney Injury Independent of Severity of Illness: A Multicenter Cohort Study. American Journal Of Kidney Diseases 2021, 77: 490-499.e1. PMID: 33422598, PMCID: PMC7791318, DOI: 10.1053/j.ajkd.2020.12.007.Peer-Reviewed Original ResearchCitationsAltmetricMeSH KeywordsAcute Kidney InjuryAgedC-Reactive ProteinCohort StudiesCOVID-19CreatinineDiureticsFemaleHospital MortalityHumansIntensive Care UnitsLength of StayMaleMiddle AgedProportional Hazards ModelsRenal DialysisRenal Insufficiency, ChronicRespiration, ArtificialRisk FactorsSARS-CoV-2Severity of Illness IndexUnited StatesVasoconstrictor AgentsUrine Uromodulin as a Biomarker of Kidney Tubulointerstitial Fibrosis
Calderon-Gutierrez F, Obeid W, Xu L, Shaw MM, Luciano RL, Kuperman M, Moeckel GW, Wilson FP, Parikh CR, Moledina DG. Urine Uromodulin as a Biomarker of Kidney Tubulointerstitial Fibrosis. Clinical Journal Of The American Society Of Nephrology 2022, 17: 1284-1292. PMID: 35948365, PMCID: PMC9625093, DOI: 10.2215/cjn.04360422.Peer-Reviewed Original ResearchCitationsAltmetricExternal Validation of an Electronic Health Record–Based Diagnostic Model for Histological Acute Tubulointerstitial Nephritis
Moledina DG, Shelton K, Menez S, Aklilu A, Yamamoto Y, Kadhim B, Shaw M, Kent C, Makhijani A, Hu D, Simonov M, O’Connor K, Bitzel J, Thiessen-Philbrook H, Wilson F, Parikh C. External Validation of an Electronic Health Record–Based Diagnostic Model for Histological Acute Tubulointerstitial Nephritis. Journal Of The American Society Of Nephrology 2024, 36: 859-868. PMID: 39500309, PMCID: PMC12059105, DOI: 10.1681/asn.0000000556.Peer-Reviewed Original ResearchCitationsAltmetric
2026
Where is the data? Delayed and chronic irAE surveillance and management after cessation of ICIs: expert insights from SITC on survivorship care and the need for long-term data
Flores T, Tonorezos E, Bhatia S, Brahmer J, Cappelli L, Cooper M, Davies M, Guild S, Gunturu K, Haanen J, Johnson D, Lacouture M, Leidner R, Mitchell S, Moledina DG, Moslehi J, Naidoo J, Obeid M, Postow M, Puzanov I, Reid M, Santomasso B, Schadendorf D, Silk A, Sullivan R, Walunas T, Wang Y, Ascierto P, Ernstoff M. Where is the data? Delayed and chronic irAE surveillance and management after cessation of ICIs: expert insights from SITC on survivorship care and the need for long-term data. Journal For ImmunoTherapy Of Cancer 2026, 14: e012823. PMID: 41775429, PMCID: PMC12958904, DOI: 10.1136/jitc-2025-012823.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsAltmetricUpdated review of Sodium Correction Rate in Hyponatremia and Hypernatremia
Moledina DG. Updated review of Sodium Correction Rate in Hyponatremia and Hypernatremia. 2026, 012026 DOI: 10.65357/001c.158150.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
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Activities
activity Kidney Precision Medicine Program: Laboratory Sub-committee
2018 - PresentProfessional OrganizationsCo-Chairactivity Kidney Precision Medicine Project: AKI adjudication committee
2023 - PresentProfessional OrganizationsCo-Chairactivity American College of Physicians: DynaMedex
2023 - PresentProfessional OrganizationsReviewerDetailsReviewer for topic: Acute tubulointerstitial nephritisactivity Yale School of Medicine
2025 - PresentCommitteesMemberDetailsIntern selection committeeactivity Kidney360 Journal
2026 - PresentJournal ServiceAssociate Editor
Honors
honor Fellow
10/07/2025National AwardNational Kidney FoundationDetailsUnited Stateshonor Top -rated abstract
01/01/2024National AwardNational Kidney FoundationDetailsUnited Stateshonor Fellow
11/19/2021National AwardAmerican Society of NephrologyDetailsUnited Stateshonor K23 Mentored Patient-Oriented Career Development Award
09/01/2018National AwardNIH/NIDDKDetailsUnited Stateshonor KPMP Opportunity Pool Travel Grant
08/10/2018National AwardKidney Precision Medicine Program (KPMP)DetailsUnited States
News
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News
- November 11, 2024Source: Medscape
Is Acute Kidney Injury Really a Single Disease?
- November 05, 2024
Clinical Trial to Help Patients Undergoing Cancer Immunotherapy
- October 25, 2024
Can a ‘Kidney Action Team’ Improve Patient Outcomes?
- July 24, 2024
Yale Department of Internal Medicine Faculty Promotions and Appointments (July 2024)