Themis Kyriakides PhD

Associate Professor of Pathology and of Biomedical Engineering; Director Graduate Programs

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development | Molecular Medicine, Pharmacology, and Physiology

School of Engineering and Applied ScienceVascular Biology and Therapeutics ProgramPathology: Kyriakides Lab; ExPathNIH T32 Program

Research Interests

Angiogenesis; Extracellular matrix remodeling; Inflammation; Cell fusion; Wound healing; Foreign body response; Gene delivery; Biomaterials more...


  • Ph.D., Washington State University, 1993

Selected Publications

  • Malik AF, Hoque R, Ouyang X, Ghani A, Hong E, Khan K, Moore LB, Ng G, Munro F, Flavell RA, Shi Y, Kyriakides TR, Mehal WZ. Inflammasome components Asc and caspase-1 mediate biomaterial-induced inflammation and foreign body response. Proc Natl Acad Sci U S A. 2011 108(50):20095-100.
  • MacLauchlan S, Yu J, Parrish M, Asoulin TA, Schleicher M, Krady MM, Zeng J, Huang PL, Sessa WC, Kyriakides TR. Endothelial nitric oxide synthase controls the expression of the angiogenesis inhibitor thrombospondin 2. Proc Natl Acad Sci U S A. 2011 108(46):E1137-45.
  • Kyriakides T.R., MacLauchlan S. (2009) The role of thrombospondins in wound healing, ischemia, and the foreign body reaction. J. Cell Comm. Signal. 3: 215-25.



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