Michael Simons, MD, FACC, FAHA
Robert W. Berliner Professor of Medicine (Cardiology) and Professor of Cell Biology; Section Chief, Cardiovascular Medicine; Director, Yale Cardiovascular Research Center
Departments & Organizations
Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development | Molecular Medicine, Pharmacology, and Physiology
Yale Medical Group
Vascular Biology and Therapeutics Program
Animal Organogenesis
Cell Biology
Internal Medicine: Cardiology: Clinical Cardiology
Research Interests
Angiogenesis; Arteriogenesis; Endothelial Signaling; tyrosine kinase signaling; vascular development; FGF; VEGF; endocytosis more...
Education
- B.S., Massachusetts Institute of Technology, 1980
- M.D., Yale University, 1984
Selected Publications
- Murakami M, Nguyen LT, Hatanaka K, Shachterle W, Chen P-Y, Zhuang ZW, Black BL, Simons M. FGF-dependent regulation of VEGF receptor 2 expression in mice. J Clin Invest, 2011: 121:2668-2678. http://www.jci.org/articles/view/44762
- Lanahan A, Hermans K, Claes F, Kerley-Hamilton JS, Zhuang ZW, Giordano FJ, Carmeliet P, Simons M. VEGF receptor 2 endocytic trafficking regulates arterial morphogenesis. Developmental Cell 2010; 18:713-724 http://www.cell.com/developmental-cell/abstract/S1534-5807(10)00160-7
- Ren B, Deng Y, Mukhopadhyay A, Lanahan AL, Zhuang ZW, Moodie KL, Mulligan-Kehoe MJ, Byzova TV, Peterson RT, Simons M. Erk1/2-Akt1 cross-talk-dependent regulation of arteriogenesis. J Clin Invest, 2010; 120:1271-1228 http://www.jci.org/articles/view/39837
