Michelle Hampson, PhD

Assistant Professor of Radiology and Biomedical Imaging; Assistant Professor of Psychiatry; Director of real-time fMRI

Research Interests

Magnetic Resonance Imaging; Neurosciences; Obsessive-Compulsive Disorder; Stress Disorders, Post-Traumatic; Video Games; Neurofeedback; Psychiatry and Psychology

Research Organizations

Radiology and Biomedical Imaging: Bioimaging Sciences: Magnetic Resonance Imaging; Magnetic Resonance Research Center

Psychiatry: Obsessive Compulsive Disorder Research Clinic

Office of Cooperative Research

Research Summary

My lab is focused on the development and application of new functional brain imaging paradigms. These include resting state functional connectivity analyses and neurofeedback via real-time fMRI (rt-fMRI). Rt-fMRI neurofeedback has great potential as a clinical treatment for mental and neurological disorders. When used in conjunction with resting state functional connectivity assessments (collected before and after the neurofeedback), it provides a powerful perturb-and-measure approach for studying human brain function.

Extensive Research Description

1. We use neurofeedback of real-time fMRI data to train patients with tic disorders, OCD, and PTSD to control clinically relevant brain activity patterns. An important question is whether this training can improve their symptoms.

2. We evaluate changes in resting state functional connectivity between brain areas before and after neurofeedback. This allows us to investigate how neurofeedback alters brain networks. Also, by correlating changes in brain connectivity with symptom changes, we can gain insight into the neural circuitry that gives rise to symptoms.

3. We are examining the correlates of video game playing in adolescents. Fast-paced game players, slow-paced game players, and non-gamers are compared in terms of their brain function (assessed using resting state functional connectivity measures) and their behavior.

Selected Publications

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Contact Info

Michelle Hampson, PhD
Mailing Address
Diagnostic RadiologyPO Box 208042
Yale MRRC, TAC-N121

New Haven, CT 06520-8042

Curriculum Vitae