Martin A Schwartz, PhD

Robert W. Berliner Professor of Medicine (Cardiology) and Professor of Biomedical Engineering and of Cell Biology

Research Organizations

Cell Biology

Internal Medicine: Cardiovascular Medicine: Yale Cardiovascular Research Center: Schwartz Lab

Vascular Biology and Therapeutics Program

Selected Publications

  • Conway DE, Breckenridge MT, Hinde E, Gratton E, Chen CS, Schwartz MA. Fluid Shear Stress on Endothelial Cells Modulates Mechanical Tension across VE-Cadherin and PECAM-1. Curr Biol. 2013 Jun 3, 23:1024-30
  • Hoffman, B.D., Grashoff, C. and Schwartz, M.A. Dynamic molecular processes mediate cellular mechanotransduction. Nature. 2011, 475:316-323.
  • Grashoff C., Hoffman BD., Brenner MD., Zhou R., Parsons M., Yang MT., McLean MA., Sligar SG., Chen CS., Ha T. and Schwartz, MA.. Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics. Nature, 2010,466:263-6.
  • Orr, A.W., Stockton, R., Simmers,M.B., Sanders, J.M., Sarembock, I.J., Blackman, B.R., Schwartz, M.A. Matrix-specific p21-activated kinase activation regulates vascular permeability in atherogenesis. J Cell Biol. 2007, 176:719-727.
  • Balasubramanian, N., Scott, D.W., Castle, J.D., Casanova, J.E., Schwartz, M.A. Arf6 and microtubules in adhesion-dependent trafficking of lipid rafts. Nat Cell Biol. 2007, 9:1381-1391.
  • Tzima, E, Irani-Tehrani, M., Kiosses, W. B., Dejana, E., Schultz, D. A., Engelhardt, B., Cao, G., DeLisser, H., Schwartz, M. A. Identification of a mechanosensory complex that mediates the endothelial cell response to fluid shear stress. Nature 2005, 437:

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Contact Info

Martin A Schwartz, PhD

The Schwartz Lab