Anthony J Koleske, PhD

Professor of Molecular Biophysics and Biochemistry

Departments & Organizations

Cancer Center, Yale: Signal Transduction

Interdepartmental Neuroscience Program

Kavli Institute for Neuroscience

Molecular Biophysics and Biochemistry: Neurobiology

Office of Student Research

Signal Transduction

WHRY Pilot Project Program Investigators

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Biochemistry, Biophysics and Structural Biology: Neurobiology | Molecular Cell Biology, Genetics and Development: Developmental Biology; Receptors and Signal Transduction | Neuroscience: Development; Molecular/Cellular Neuroscience | Principal Investigator


Anthony J. Koleske is an expert in understanding the biochemical mechanisms that control changes in cell shape and movement. After receiving a B.S. in Biochemistry and Molecular Biology at the University of Wisconsin-Madison, Dr. Koleske performed his Ph.D. studies with Dr. Richard Young at the Whitehead Institute/Massachusetts Institute of Technology. For his Ph.D. thesis, Dr. Koleske discovered the RNA polymerase II holoenzyme, an important advancement in understanding how gene transcription is turned on. Dr. Koleske went on to do a postdoctoral fellowship with Nobel Laureate Dr. David Baltimore at M.I.T., where he began his work studying cellular functions of Abl family kinases, which his laboratory has shown are essential regulators of the cytoskeleton in diverse cell types.Dr. Koleske joined the Department of Molecular Biophysics and Biochemistry at Yale University in 1998, where he currently is Professor and holds a joint appointment in the Department of Neurobiology. Dr. Koleske is the recipient of numerous awards including a Jane Coffin Childs Postdoctoral Fellowship, Special Fellowship and Scholar Awards from the Leukemia and Lymphoma Society, a NARSAD Young Investigator Award, and an Established Investigator Award from the American Heart Association.He has served widely on review panels, including terms as Chair of the Basic Science Study Section for the American Heart Association and the Neurodifferentiation, Plasticity, Repair, and Rhythmicity Study Section of the NIH. He currently directs the combined Ph.D. programs in the Biological and Biomedical Sciences at Yale, the China Scholarship Council-Yale World Scholars Program, and co-directs (with Mike Nitabach) the Medical Research Scholars Program at Yale. He is married to Ruth Koleske and is father to twins Ben and Emily.

Education & Training

PhD Massachusetts Institute of Technology (1993)
BS University of Wisconsin (1988)

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