Keith Hawkins, PsyD
Professor of PsychiatryCards
Appointments
Additional Titles
Director, Neuropsychological Assessment Service, Connecticut Mental Health Center, Psychiatry
Contact Info
Appointments
Additional Titles
Director, Neuropsychological Assessment Service, Connecticut Mental Health Center, Psychiatry
Contact Info
Appointments
Additional Titles
Director, Neuropsychological Assessment Service, Connecticut Mental Health Center, Psychiatry
Contact Info
About
Titles
Professor of Psychiatry
Director, Neuropsychological Assessment Service, Connecticut Mental Health Center, Psychiatry
Biography
Prior to coming to the US for advanced training Professor Hawkins worked as a sailing journalist, college counselor, and psychology tutor and lecturer in colleges and universities in New Zealand and Australia. He is the Director of the Neuropsychological and Psychological Assessment Service of the Connecticut Mental Health Center, where he has trained an estimated 70 pre and postdoctoral fellows, several now full professors. Dr. Hawkins has additionally supervised T32 postdoctoral fellows and mentored faculty with NIH career development awards. During his career Dr. Hawkins has consulted to the Yale New Haven Hospital (YNHH) Adler Geriatric Clinic, and to the Memory Disorders Clinic of the Institute of Living/Hartford Hospital, on early dementia detection and differential diagnosis, and has held numerous training and consulting contracts with external hospitals. He assesses medical practitioners for the YNHH Late Career Program, with over 480 evaluations to date, and consults to YNHH medical leadership and credentialing officials on matters of cognitive competence among practitioners who serve the hospital.
Dr. Hawkins has held editorial board appointments for several neuropsychological, neuropsychiatric, and neurology journals, and consulted weekly to the Olin Neuropsychiatric Research Center (ONRC) in Hartford (ongoing), and the Institute for Neurodegenerative Disorders (IND) for approximately a decade. He is an author on 88 papers (h index = 42, total citations 7,275+). Among other scholarly engagements, Dr. Hawkins has studied cognitive aging in 350 older African Americans, many within their own homes, community centers, and churches. He has collaborated with Dr. Chris van Dyck in a study of executive functioning in the elderly, and within the P50 Alzheimer's Disease Research Center at Yale. During his consultation to IND he participated in amyloid imaging and immunotherapy trials, and oversaw the neuropsychological components of several Parkinson’s Disease studies. He has been Yale subcontract Principal Investigator for the Hartford Healthcare Corporation funded study, “Midlife vascular risk factors and the development of cognitive impairment, cerebrovascular disease and preclinical dementia”, and has designed and overseen the neuropsychological component of numerous large-scale studies. This includes selecting tests, finalizing the neuropsychological manual, and conducting training for the 22 site international study of early stage Parkinson’s disease (the $60 million Parkinson Progression Markers Initiative, PPMI). At the ONRC he has collaborated with Drs. Godfrey Pearlson and Michael Stevens in studies of psychosis, the neural underpinnings of developing executive capacities in adolescence, the effects of alcohol on the late adolescent brain, and, currently, the effects of marijuana on driving. Earlier he was a collaborator with Drs. Scott Woods and Thomas McGlashan of Yale, and faculty across USA and Canada, in studies of the schizophrenia prodrome, including the first ever double-blind treatment trial. He collaborated with the late Dr. Ralph Hoffman and Dr. William Sledge in studies of the linguistic characteristics of disordered speech, and, with Dr. Hoffman, the efficacy of transcranial magnetic stimulation (TMS) as a treatment for refractory hallucinations. Other recent activities include collaborations with Dr. Hochang Lee in studies of cardiac surgery patients. Throughout his career Dr. Hawkins has researched the psychometric properties and inference validity of neuropsychological tests, including analyses of the clinical utility of the six-factor revision of the widely used Wechsler intellectual and memory batteries. In concert with the eminent neuropsychologists who implemented this new direction in intelligence and memory testing, Dr. Hawkins presented at national and international conferences on clinical interpretation.
Appointments
Psychiatry
Professor Phased RetirementPrimary
Other Departments & Organizations
- Alzheimer's Disease Research Center (ADRC)
- Connecticut Mental Health Center
- Division of Aging & Geriatric Psychiatry
- Neuropsychological and Psychological Assessment Service
- Psychiatry
- Psychology Section
- Yale Ventures
Education & Training
- Postdoctoral Training/Instructorship
- Harvard University (1989)
- Internship
- Brown University School of Medicine (1987)
- PsyD
- Rutgers University (1987)
- MPhil
- Massey University (New Zealand) (1980)
- BA
- Massey University (New Zealand) (1975)
Research
Overview
Research activities have included:
- CNS correlates of metabolic syndrome
- Effect of college age drinking on the developing brain
- Marijuana and driving
- Cognitive course after left ventricular assistive device cardiac surgery
- Investigator, Yale Alzheimer's Disease Research Center
- Cognitive features of prodromal disease states
- Psychometric properties of neuropsychological tests
- Validity of various methods of inference in neuropsychology
ORCID
0000-0003-3494-2103
Research at a Glance
Yale Co-Authors
Publications Timeline
Godfrey Pearlson, MA, MBBS
John Krystal, MD
Michael Stevens, PhD
Kun Wu, MD, PhD
Anderson M. Winkler, MD, DPhil
Bruce E Wexler, MD
Publications
2024
75. Executive Working Memory Intervention Reduces Motor Activity in Adolescents With Attention-Deficit Hyperactivity Disorder
Beatty M, Sullivan A, Anderson J, Choi J, Pearlson G, Hawkins K, Bond D, Stevens M. 75. Executive Working Memory Intervention Reduces Motor Activity in Adolescents With Attention-Deficit Hyperactivity Disorder. Biological Psychiatry 2024, 95: s130. DOI: 10.1016/j.biopsych.2024.02.310.Peer-Reviewed Original Research
2023
Age-related, multivariate associations between white matter microstructure and behavioral performance in three executive function domains
Anderson J, Calhoun V, Pearlson G, Hawkins K, Stevens M. Age-related, multivariate associations between white matter microstructure and behavioral performance in three executive function domains. Developmental Cognitive Neuroscience 2023, 64: 101318. PMID: 37875033, PMCID: PMC10618425, DOI: 10.1016/j.dcn.2023.101318.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsExecutive function domainsResponse inhibitionWhite matter microstructureLower response inhibitionStructure-cognition relationshipsEF abilitiesBehavioral performanceCognitive imbalanceNeurocognitive testsFunction domainTest performanceYoung adulthoodFractional anisotropyBrain changesAge 12Young adultsSS performanceWhite matter FA valuesGreater relianceWhite matter changesWhite matter microstructural differencesSubjects ages 12White matter skeletonIndependent componentsMultivariate associations
2022
P436. Multivariate Associations Between White Matter Microstructure Development and Normative Gains in Three Executive Function Domains
Anderson J, Hawkins K, Pearlson G, Stevens M. P436. Multivariate Associations Between White Matter Microstructure Development and Normative Gains in Three Executive Function Domains. Biological Psychiatry 2022, 91: s264. DOI: 10.1016/j.biopsych.2022.02.672.Peer-Reviewed Original Research
2020
Depression predicts cognitive and functional decline one month after coronary artery bypass graft surgery (Neuropsychiatric Outcomes After Heart Surgery study)
Oldham MA, Lin I, Hawkins KA, Li F, Yuh DD, Lee HB. Depression predicts cognitive and functional decline one month after coronary artery bypass graft surgery (Neuropsychiatric Outcomes After Heart Surgery study). International Journal Of Geriatric Psychiatry 2020, 36: 452-460. PMID: 33022808, PMCID: PMC9326959, DOI: 10.1002/gps.5443.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCoronary artery bypass graft surgeryArtery bypass graft surgeryBypass graft surgeryCABG surgeryGraft surgeryCDR-SBProspective observational cohort studyOlder ageOne monthHamilton Depression Rating ScaleClinical Dementia Rating SumHeart Surgery studyObservational cohort studyDepression Rating ScaleSemi-structured clinical interviewTotal study sampleHopkins Verbal Learning TestPostoperative deliriumPreoperative depressionWord Fluency TestCohort studyVerbal Learning TestNeuropsychiatric outcomesTertiary careFunctional outcomeNeuropsychiatric symptoms and cognitive abilities over the initial quinquennium of Parkinson disease
Weintraub D, Caspell‐Garcia C, Simuni T, Cho HR, Coffey CS, Aarsland D, Alcalay RN, Barrett MJ, Chahine LM, Eberling J, Espay AJ, Hamilton J, Hawkins KA, Leverenz J, Litvan I, Richard I, Rosenthal LS, Siderowf A, York M, Initiative P. Neuropsychiatric symptoms and cognitive abilities over the initial quinquennium of Parkinson disease. Annals Of Clinical And Translational Neurology 2020, 7: 449-461. PMID: 32285645, PMCID: PMC7187707, DOI: 10.1002/acn3.51022.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsParkinson's disease participantsNeuropsychiatric symptomsParkinson's diseaseHealthy controlsCognitive impairmentMedication useYear 5Anticholinergic medication useCross-sectional prevalenceParkinson's disease patientsHypnotic useDisease patientsNeuropsychiatric featuresDisease onsetAnnual visitsSymptomsDisorder subtypesAbsolute prevalenceDiseaseTime pointsPrevalenceBaselineImpairmentParticipantsOnset
2019
DEPRESSION PREDICTS DELIRIUM AFTER CORONARY ARTERY BYPASS GRAFT SURGERY INDEPENDENT OF COGNITIVE IMPAIRMENT AND CEREBROVASCULAR DISEASE: AN ANALYSIS OF THE NOAHS STUDY
Lin I, Oldham M, Hawkins K, Scoutt L, Yuh D, Lee H. DEPRESSION PREDICTS DELIRIUM AFTER CORONARY ARTERY BYPASS GRAFT SURGERY INDEPENDENT OF COGNITIVE IMPAIRMENT AND CEREBROVASCULAR DISEASE: AN ANALYSIS OF THE NOAHS STUDY. American Journal Of Geriatric Psychiatry 2019, 27: s160-s161. DOI: 10.1016/j.jagp.2019.01.113.Peer-Reviewed Original ResearchCitationsConceptsMiddle cerebral arteryMild cognitive impairmentCerebrovascular diseaseCognitive impairmentRisk factorsCoronary artery bypass graft surgeryStenosis severityArtery bypass graft surgeryBilateral middle cerebral arteriesPreoperative cognitive assessmentBypass graft surgeryConfusion Assessment MethodCoronary artery bypassRisk of deliriumDelirium risk factorsObservational cohort studyPostoperative day 2Clinical Dementia RatingPutative risk factorsResults Average ageCI 1.3Preoperative depressionStructured HamiltonStudy psychiatristArtery bypass
2018
Depression Predicts Delirium After Coronary Artery Bypass Graft Surgery Independent of Cognitive Impairment and Cerebrovascular Disease: An Analysis of the Neuropsychiatric Outcomes After Heart Surgery Study
Oldham MA, Hawkins KA, Lin IH, Deng Y, Hao Q, Scoutt LM, Yuh DD, Lee HB. Depression Predicts Delirium After Coronary Artery Bypass Graft Surgery Independent of Cognitive Impairment and Cerebrovascular Disease: An Analysis of the Neuropsychiatric Outcomes After Heart Surgery Study. American Journal Of Geriatric Psychiatry 2018, 27: 476-486. PMID: 30709616, PMCID: PMC6443412, DOI: 10.1016/j.jagp.2018.12.025.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsMiddle cerebral arteryMild cognitive impairmentCerebrovascular diseaseCognitive impairmentRisk factorsCoronary artery bypass graft surgeryStenosis severityProspective observational cohort studyArtery bypass graft surgeryBilateral middle cerebral arteriesTertiary care academic hospitalHeart Surgery studyPreoperative cognitive assessmentUndergoing CABG surgeryBypass graft surgeryConfusion Assessment MethodRisk of deliriumDelirium risk factorsObservational cohort studyPostoperative day 2Clinical Dementia RatingDepression InterviewPreoperative depressionStructured HamiltonStudy psychiatristThe effect of age and smoking on the hippocampus and memory in late middle age
Hawkins KA, Emadi N, Pearlson GD, Taylor B, Khadka S, King D, Blank K. The effect of age and smoking on the hippocampus and memory in late middle age. Hippocampus 2018, 28: 846-849. PMID: 30070068, DOI: 10.1002/hipo.23014.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSmoking historyHippocampal volumeHeavy smoking historyVascular risk factorsMiddle-aged subjectsMRI brain scanningAPOE e4 genotypeEffect of ageHeavy smokingHippocampal atrophyAlcohol historyRisk factorsE4 genotypeBrain scanningAPOE e4Neuropsychological assessment batteryHippocampus atrophyFemale subjectsGlobal cognitionMemory disordersData extractionMemory declineAssessment BatteryAgeSmokingCognition among individuals along a spectrum of increased risk for Parkinson’s disease
Chahine LM, Urbe L, Caspell-Garcia C, Aarsland D, Alcalay R, Barone P, Burn D, Espay AJ, Hamilton JL, Hawkins KA, Lasch S, Leverenz JB, Litvan I, Richard I, Siderowf A, Coffey CS, Simuni T, Weintraub D, Initiative T. Cognition among individuals along a spectrum of increased risk for Parkinson’s disease. PLOS ONE 2018, 13: e0201964. PMID: 30125297, PMCID: PMC6101368, DOI: 10.1371/journal.pone.0201964.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsParkinson's diseaseIdiopathic REM sleep behavior disorderParkinson's Progression Markers Initiative (PPMI) studyDe novo Parkinson's diseaseREM sleep behavior disorderDopamine transporterNon-motor symptomsNovo Parkinson's diseaseSleep behavior disorderNon-motor featuresSymbol Digit Modalities TestBaseline neuropsychological performanceMontreal Cognitive AssessmentFuture neurodegenerationLewy bodiesInclusion criteriaSpectrum of riskMutation carriersInitiative studyCohortBehavior disorderCognitive functionCognitive test scoresModalities TestNeuropsychological performanceGuanfacine treatment for prefrontal cognitive dysfunction in older participants: a randomized clinical trial
Barcelos NM, Van Ness PH, Wagner AF, MacAvoy MG, Mecca AP, Anderson GM, Trentalange M, Hawkins KA, Sano M, Arnsten AFT, van Dyck CH. Guanfacine treatment for prefrontal cognitive dysfunction in older participants: a randomized clinical trial. Neurobiology Of Aging 2018, 70: 117-124. PMID: 30007160, PMCID: PMC6503670, DOI: 10.1016/j.neurobiolaging.2018.05.033.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsDose of guanfacineQuality of lifeZ-scoreCognitive functionPrefrontal cognitive dysfunctionCommon adverse eventsPrimary outcome measureRandomized clinical trialsGlobal functionOlder participantsHealthy older participantsPrefrontal cognitive functionDry mouthAdverse eventsAgonist guanfacineClinical trialsGuanfacine treatmentCognitive dysfunctionMean changeOutcome measuresPlaceboGuanfacineOlder individualsWeeksDose
Links & Media
Media
- White matter lesions in a 57 year old with a BMI of 36, hypertension (135/100), and diabetes type 2 (HbA1c = 7.6). Vascular risk factors are associated with white matter lesions, which negatively correlate with cognition. Hawkins et al. Metab Brain Dis, 32(3), 849-857. doi: 10.1007/s11011-017-9980-9
News
- November 14, 2016
Yale Psychological Medicine Service sends several members to APM annual meeting
- June 01, 2006
Grants and contracts awarded to Yale School of Medicine, November/December 2005
- January 27, 2003
Magnetic Stimulation Helps Alleviate Auditory Hallucinations, Yale Study Shows
- March 08, 2001
Study of Schizophrenia Patients Who Hear "Voices" to Continue at Yale With Over $600,000 in Grants from NIMH, Dana and Donaghue Foundations
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Psychiatry
34 Park St
New Haven, CT 06519-
United States