Daniel Robert Rubio, MD
Assistant Professor of OrthopaedicsCards
About
Research
Publications
2024
P27. Renal transplant patients at increased odds off many perioperative adverse events following lumbar laminotomy/discectomy
Gouzoulis M, Seddio A, Zhu J, Day W, Jabbouri S, Rubio D, Grauer J. P27. Renal transplant patients at increased odds off many perioperative adverse events following lumbar laminotomy/discectomy. The Spine Journal 2024, 24: s76. DOI: 10.1016/j.spinee.2024.06.048.Peer-Reviewed Original ResearchSevere adverse eventsHistory of renal transplantationUrinary tract infectionRenal transplantationAcute kidney injuryAdverse eventsMinor adverse eventsElixhauser Comorbidity IndexIncreased oddsCurrent Procedural TerminologyTract infectionsLumbar discectomyKidney injuryED visitsIncreased odds of acute kidney injuryOdds of acute kidney injuryOdds ratioOdds of ED visitsKaplan-Meier survival curvesDays of follow-upRenal transplant groupRenal transplant patientsIncidence of reoperationRisk of reoperationOdds of sepsisP31. Testosterone replacement therapy associated with increased 90-day postoperative adverse events and 5-year reoperation following lumbar discectomy
Seddio A, Gouzoulis M, Smith-Voudouris J, Rubio D, Day W, Grauer J. P31. Testosterone replacement therapy associated with increased 90-day postoperative adverse events and 5-year reoperation following lumbar discectomy. The Spine Journal 2024, 24: s78. DOI: 10.1016/j.spinee.2024.06.052.Peer-Reviewed Original ResearchTestosterone replacement therapyAcute kidney injuryLumbar discectomyAdverse eventsMale patientsOdds ratioCurrent Procedural TerminologyReoperation ratePostoperative outcomesElixhauser Comorbidity IndexPostoperative recoveryMultivariate analysisSingle-level lumbar discectomyTestosterone replacement therapy patientsMyocardial infarctionOrthopedic surgeryKaplan-Meier survival analysisEmergency departmentLumbar spinal proceduresLog-rank testMonths of surgeryRetrospective cohort studyPostoperative adverse eventsEnhanced postoperative recoveryMinor adverse events35. Comparable risk of adverse events following cervicothoracic interlaminar and transforaminal epidural injections: an analysis of 1.29 million patients
Seddio A, McNamara K, Gouzoulis M, Jabbouri S, Ratnasamy P, Rubio D, Grauer J. 35. Comparable risk of adverse events following cervicothoracic interlaminar and transforaminal epidural injections: an analysis of 1.29 million patients. The Spine Journal 2024, 24: s19. DOI: 10.1016/j.spinee.2024.06.478.Peer-Reviewed Original ResearchAdverse eventsSpinal neurologic deficitsStatistically significant differenceCurrent Procedural TerminologyElixhauser Comorbidity IndexEpidural injectionAdult patientsNeurological deficitsAdverse outcomesMultivariate analysisED visitsIncidence of adverse eventsEpidural spinal injectionsTransforaminal epidural injectionsEmergency departmentTransforaminal (TFRisk of adverse eventsSignificant differenceRetrospective cohort studyMinor adverse eventsSampled adult patientsOutcome measures IncidencePotential adverse eventsSpinal injectionPatient age100. Semaglutide associated with improved postoperative outcomes following single-level posterior lumbar fusion for patients with type II diabetes
Seddio A, Gouzoulis M, Vasudevan R, Dhodapkar M, Jabbouri S, Zhu J, Rubio D, Grauer J. 100. Semaglutide associated with improved postoperative outcomes following single-level posterior lumbar fusion for patients with type II diabetes. The Spine Journal 2024, 24: s52-s53. DOI: 10.1016/j.spinee.2024.06.543.Peer-Reviewed Original ResearchSingle-level posterior lumbar fusionPosterior lumbar fusionSodium-glucose transport protein 2 inhibitorsImpact of semaglutideHospital readmissionPostoperative outcomesElixhauser Comorbidity IndexED visitsT2DM patientsCurrent Procedural TerminologyEmergency departmentLumbar fusionAdverse eventsOdds of hospital readmissionOutcome measures IncidenceRisk of type I errorInferior postoperative outcomesDiagnosis of T2DMMonths of surgeryYear of surgeryRetrospective cohort studyMinor adverse eventsType II diabetes mellitusMatched 1:4Management of diabetesUtilization and timing of surgical intervention for central cord syndrome in the United States
Dhodapkar M, Halperin S, Seddio A, Dahodwala T, Rubio D, Grauer J. Utilization and timing of surgical intervention for central cord syndrome in the United States. European Spine Journal 2024, 1-7. PMID: 39103615, DOI: 10.1007/s00586-024-08431-2.Peer-Reviewed Original ResearchCentral cord syndromeSurgical interventionAbsence of bony injuryOperative interventionCord syndromeBony injuriesPredictors of operative managementAbsence of vertebral fracturesTiming of surgical interventionTiming of operative interventionCohort of patientsProportion of patientsDays of diagnosisHigher comorbidity burdenVertebral fracturesSpinal cord injuryMethodsAdult patientsNon-operativelyNonsurgical interventionsMultivariate analysisStudy assessed utilizationComorbidity burdenIncomplete spinal cord injuryPatientsInclusion criteriaRobotic Versus Navigation Assisted Posterior Lumbar Fusion: A National Database Study.
Gouzoulis M, Seddio A, Winter A, Jabbouri S, Zhu J, Rubio D, Varthi A, Grauer J. Robotic Versus Navigation Assisted Posterior Lumbar Fusion: A National Database Study. Spine 2024 PMID: 38717329, DOI: 10.1097/brs.0000000000005032.Peer-Reviewed Original ResearchPosterior lumbar fusionLumbar fusionAdverse eventsLevel posterior lumbar fusionsCPT codesKaplan-Meier survival analysisRate of reoperationNavigation-assisted surgeryRobotic-assisted casesNavigation-assistedMinor adverse eventsPerioperative adverse eventsMultivariate logistic regressionICD-10 procedure codeRobotic cohortRobotic assistanceSpinal navigationReoperation rateAnterior fusionElixhauser Comorbidity IndexPearlDiver databaseNo significant differenceIncremental advantageAdverse outcomesComorbidity indexCefazolin Alone Versus Cefazolin with Tobramycin or Gentamicin as Intraoperative Antibiotic Prophylaxis for Single-Level Posterior Lumbar Fusion
Dhodapkar M, Jeong S, Halperin S, Rubio D, Li M, Grauer J. Cefazolin Alone Versus Cefazolin with Tobramycin or Gentamicin as Intraoperative Antibiotic Prophylaxis for Single-Level Posterior Lumbar Fusion. JAAOS Global Research And Reviews 2024, 8: e24.00082. PMCID: PMC11068128, DOI: 10.5435/jaaosglobal-d-24-00082.Peer-Reviewed Original ResearchSingle-level posterior lumbar fusionPosterior lumbar fusionSurgical site infectionElixhauser Comorbidity IndexLumbar fusionAntibiotic prophylaxisAdverse outcomesAntibiotic prophylaxis regimenAntibiotic prophylaxis regimensIntraoperative antibiotic prophylaxisRevision ratePerioperative antibiotic prophylaxisPostoperative adverse outcomesPosterior lumbar fusion patientsMultivariate logistic regressionProphylaxis regimensProphylaxis regimenPatient ageSite infectionUnivariate analysisCefazolinComorbidity indexMultivariate analysisAntibiotic subgroupsTraumatic diagnoses
2023
Low Back Pain: Utilization of Urgent Cares Relative to Emergency Departments
Dhodapkar M, Modrak M, Halperin S, Gouzoulis M, Rubio D, Grauer J. Low Back Pain: Utilization of Urgent Cares Relative to Emergency Departments. Spine 2023, 49: 513-517. PMID: 37982595, DOI: 10.1097/brs.0000000000004880.Peer-Reviewed Original ResearchLow back painElixhauser Comorbidity IndexUrgent care centersEmergency departmentUrgent careBack painED visitsED utilizationCare centerAdvanced imagingUrgent care useUrgent care visitsDays of diagnosisSetting of traumaSpinal cord injuryYears of ageComorbidity indexInfectious diagnosisCare visitsLBP patientsMost patientsRecent surgeryAdult patientsPatient ageED patientsComment on: Investigation of the effect of weight loss after laparoscopic sleeve gastrectomy on Cobb angle, waist and back pain: a prospective study
Jabbouri S, Gibbs K, Rubio D. Comment on: Investigation of the effect of weight loss after laparoscopic sleeve gastrectomy on Cobb angle, waist and back pain: a prospective study. Surgery For Obesity And Related Diseases 2023, 19: 1365-1366. PMID: 37953127, DOI: 10.1016/j.soard.2023.10.002.Peer-Reviewed Original ResearchImaging in spinal infections: Current status and future directions
Dhodapkar M, Patel T, Rubio D. Imaging in spinal infections: Current status and future directions. North American Spine Society Journal (NASSJ) 2023, 16: 100275. PMID: 37822347, PMCID: PMC10562850, DOI: 10.1016/j.xnsj.2023.100275.Peer-Reviewed Original Research
Academic Achievements and Community Involvement
Clinical Care
Overview
Daniel Rubio, MD, is a board-certified, fellowship-trained orthopaedic spine surgeon and assistant professor of orthopaedic surgery at Yale School of Medicine. He is co-medical director of the Spine Center at Yale New Haven Hospital and associate vice chair of clinical affairs in the Department of Orthopaedics at Yale School of Medicine.
He specializes in treating conditions of the neck and back, including spinal deformity, spine tumors and metastatic disease, spine trauma, infections of the spine, and degenerative conditions. He treats both adult and pediatric patients.
He received his Medical Doctorate from Drexel University where he graduated Alpha Omega Alpha. He completed Residency in Orthopaedic Surgery at Yale University School of Medicine and Fellowship in Combined Neurosurgery/Orthopaedic Spine Surgery at Washington University in Saint Louis. He also completed the AO North America Spine Fellowship.
Dr. Rubio is actively involved in both clinical and basic science research. He holds a patent for a novel diagnostic test for neurodegenerative diseases, and has published research on various orthopaedic and spine conditions with an emphasis on optimizing patient outcomes. His research and that of his collaborators have been presented at regional, national, and international conferences. He teaches students and residents at Yale School of Medicine.
Dr. Rubio believes in a patient-centered approach to care including both surgical and non-surgical means to return his patients to a pain-free and active lifestyle. He sees patients at the Yale Spine Center (New Haven) and the Guilford Orthopaedic Surgery office location. He performs surgery at both Yale New Haven Hospital (York St.) and Yale-Saint Raphael Campus.
Clinical Specialties
Fact Sheets
Spinal Deformity
Learn More on Yale MedicineMinimally Invasive Spinal Surgery
Learn More on Yale MedicineHalo-Gravity Traction
Learn More on Yale MedicineNerve Blocks For Surgery
Learn More on Yale Medicine
Board Certifications
Orthopaedic Surgery
- Certification Organization
- AB of Orthopaedic Surgery
- Original Certification Date
- 2022
Yale Medicine News
Links & Media
News
- February 27, 2023Source: NBC Connecticut
Yale Doctors Explain How to Avoid Top Winter Injuries
- February 15, 2023Source: Yale Medicine
Compression Fractures, Strains, and Falls: How to Prevent Winter Back Injuries
- May 11, 2022
New Spine Robot to Serve as Backbone for Orthopaedic Innovations in Personalized Medicine
- August 05, 2021Source: Yale Medicine
Back Pain: Bad Posture or a Different Problem?