Current, Future, & Past Issues
Upcoming Issues
December 2025: Neglected Tropical Diseases and Parasites
March 2026: Neurodevelopment and Neurodegeneration
June 2026: Gene Therapies and Rare Diseases (submission deadline: Feb 1, 2026)
September 2026: Mitochondria in Health and Disease (submission deadline: Jun 1, 2026)
This issue's cover takes inspiration from Keith Haring, an activist-artist whose work dealt intimately with themes of community, othering, disease, and sexuality. These themes are especially significant to the history of medicine; societal structures have led to abuses of power and marginalization of vulnerable communities with regards to healthcare access and practices, while the power of community to enact change is proven and essential. In Keith Haring's richly symbolic style, the cover depicts themes of social justice and community activism, racial and colonial bias in healthcare, conversion therapy and the “queer gene,” psychiatric healthcare and reform, zootherapy, sexism and fertility issues in healthcare, and community-based healthcare services.
Cover and caption by Peter Harris.
Deputy Editors for September 2025: History of Medicine
Hayley Serpa, Program in the History of Science and Medicine, Yale University, and Shivesh Shourya, MPH ’25, Yale School of Public Health
Editor Picks
Architecture of Neurology: Establishment of the Montreal Neurological Institute as a Transnational History
Uğurgül Tunç
Weaving MAPS: Historiographical Perspectives on Writing Postcolonial Histories of the Modern Hospital
Joseph Aaron S. Joe
“A Better Way”: The Evolution of Community-Based AIDS Health Services in Birmingham, Alabama, 1985-2000
Kendall T. Comish
Healing Histories and Breaking Barriers for Asian Women at the Yale School of Medicine
An Interview with Qi Yan and Xuezhu (Sunny) Wang
Hayley Serpa and Samuel Suh
2025 Issues
This issue's cover takes inspiration from Keith Haring, an activist-artist whose work dealt intimately with themes of community, othering, disease, and sexuality. These themes are especially significant to the history of medicine; societal structures have led to abuses of power and marginalization of vulnerable communities with regards to healthcare access and practices, while the power of community to enact change is proven and essential. In Keith Haring's richly symbolic style, the cover depicts themes of social justice and community activism, racial and colonial bias in healthcare, conversion therapy and the “queer gene,” psychiatric healthcare and reform, zootherapy, sexism and fertility issues in healthcare, and community-based healthcare services.
Cover and caption by Peter Harris.
At the core of epigenetics are mechanisms that selectively control genome accessibility and availability. Molecular marks and tags shift the genome architecture, dynamically yet precisely opening up or coiling DNA to modulate gene expression. This ethereal and surrealist-inspired cover art depicts a DNA strand in motion – sequentially coiling around histones and eventually transitioning into a chromosome. The context or environment driving these changes is left obscure, represented by a psychedelic background that blends from underwater to interstellar. The June 2025 issue covers epigenetic mechanisms with fundamental and translational perspectives, examining their impact at the level of cells to organisms and communities.
Caption by Deputy Editors Reem Abu-Shamma and Andriana Marijic Buljubasic.
Cover art by Peter Harris.
Kinase activities underpin dynamic signaling processes in cells that are essential for them to grow and respond to their environment. For example, the first reaction of glycolysis – a fundamental basis for energy generation across living things – is catalyzed by a kinase called hexokinase. Here, we have depicted a tree of life with hexokinase at its roots, which is converting glucose to glucose-6-phosphate. The overall cover is inspired by the art nouveau style of Alphonse Mucha; the tree itself is ringed by circular panels that show the cellular products arising from hexokinase and the glycolysis reaction; from ATP to nucleotides, mitochondria, cellular organisms, fungi, plants, animals, and humans. We hope readers are inspired by the ways in which the study of kinase signaling unites molecular, cellular, and organismal-level perspectives.
Caption by Peter Harris, Rahul Gupta, and Ingrid Heumann.
Cover art by Peter Harris.
2024 Issues
Stylized journal cover art featuring a human bust with exaggerated halftone dots, resembling an electron micrograph. A stream of antibodies winds through clusters of yellow-orange viruses, with the changing color reflecting the viruses’ influence. As the antibodies reach the human bust, they become red, which symbolizes the chaotic and dangerous autoimmune response.
Original cover design by Peter Harris.
Caption by Peter Harris, RuthMabel Boytz, and Evan Navori.
Just like a spectrum of light can be combined into white light, integrative medicine draws from a variety of traditions and practices to tackle mental and physical wellbeing in a way that addresses patients' needs from diagnosis through recovery. Depicted in this cover are just some of these practices; therapy and group support, herbal supplements, cellular biology research, Chinese medicinal traditions, genetic scenery, and wellness & mindfulness practices. Caption and original cover design by Peter Harris.
Integrative Medicine – September 2024
Individuals with a chronic disease face a challenging landscape on their journey to meet with healthcare providers and often face under-acknowledged internal and external obstacles on the route to seeking help. While these experiences may be clear to individual patients, the shared commonalities across different chronic diseases are less connected in the literature as the very nature of what constitutes a chronic disease continues to be debated. This issue features discussions and research findings relevant across the umbrella of chronic disease, uniting topics from patient perspectives to emerging therapeutics. Caption by Noah Yann Lee and Bassel Shanab. Original cover design by Peter Harris.
Pregnancy is a time of radical and rapid change with acute implications for the health of expecting parents and child, from conception well into the postpartum period. The physiological changes brought about by pregnancy, education about healthcare options, and social support both before and after birth are just some of the factors that can have a drastic impact on the success of a pregnancy and the child's development. This issue explores how we can better understand pregnancy's impact on emotional and physical wellbeing, and how outcomes might be improved for the experience that began all our lives. Caption by Peter Harris. Original cover design by Peter Harris.
2023 Issues
From the ATCG sequences of our genetic code to the detailed chronicles of our healthcare encounters, the pulse of life is ever being captured in "Big Data." In this realm of boundless 1s and 0s, the world of medicine finds itself at the heart of the data revolution. We invite you into this issue as we explore the ever-evolving techniques researchers are deploying to grapple with big data and discern critical patterns that have the potential to revolutionize clinical decision-making and patient care. Caption by Conrad Safranek. Original cover design by Peter Harris.
Our world is evolving drastically from the effects of man-made climate change. As our environment changes, we continue to face new healthcare challenges; from physical ailments, to mental health issues, to climate and medical justice obligations. This cover draws inspiration from the extraordinary images that recently came out of the East coast of the United States, as wildfires in Canada brought an unprecedented level of atmospheric pollution to major population centers. Events like these serve as a stark reminder that our planet is changing, and that we must urgently work to address both the causes of climate change and the health issues arising from it. Caption by Peter Harris. Original cover design by Peter Harris.
2022 Issues
Antimicrobial Resistance - December 2022
The field of Bioethics rests on four pillars: patient autonomy, beneficence, nonmaleficence, and social justice. In this cover, a figure wielding a staff resembling the rod of Asclepius stands at a compass, which points towards architecture representing these four values. Caption and original cover design by Peter Harris.
Bioethics - September 2022
Vaccines – June 2022
The Science of Stress - March 2022
2021 Issues
Rare Disease - December 2021
Health Equity - September 2021
Zoonotic Disease - June 2021
Preventive Medicine - March 2021
2020 Issues
Allergic Diseases and Type II Immunity - December 2020
Sex and Reproduction - September 2020
Medical Education - August 2020
Plant-based Medicine and Pharmacology - June 2020
Skin - March 2020
2019 Issues
Death - December 2019
Organelles - September 2019
Clocks and Cycles - June 2019
Attention Science - March 2019
2018 Issues
Ecology and Evolution - December 2018
Medical Technology - September 2018
Nutrition and Food Science - June 2018
Sensory Biology and Pain - March 2018
2017 Issues
Gene Editing - December 2017
Comparative Medicine - September 2017
Infectious Diseases - June 2017
Drug Development - March 2017
2016 Issues
Epigenetics - December 2016
The Microbiome - September 2016
Sex and Gender Health - June 2016
The Aging Brain - March 2016
2015 Issues
Personalized Medicine - December 2015
Addiction - September 2015
A Multifaceted Battle Against Cancer - June 2015
Autism Spectrum Disorders - March 2015