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Trial on Efficacy and Safety of Pritelivir Tablets for Treatment of Acyclovir-resistant Mucocutaneous HSV (Herpes Simplex Virus) Infections in Immunocompromised Adults (PRIOH-1)

Conditions

Infectious Diseases | Men's Health | Women's Health

Phase II

What is the purpose of this trial?

A randomized, open-label, multi-center, comparative trial, to assess the efficacy and safety of Pritelivir versus Foscarnet for the treatment of acyclovir-resistant mucocutaneous HSV infections in immunocompromised subjects (PRIOH-1)

Pritelivir will be provided as 100 mg film-coated tablets. Pritelivir will be administered as a loading dose of 400 mg (4 x 100 mg) as first dose followed by a maintenance dose of 100 mg once daily (qd). Foscarnet will be given as intermittent infusions at a dose of 40 mg/kg every 8 hours or 60 mg/kg every 12 hours for a minimum of one hour duration for a maximum treatment duration of 28 days.

  • Trial with
    AiCuris Anti-infective Cures GmbH
  • Start Date
    04/01/2018
  • End Date
    11/30/2023

I'm interested in volunteering

If you would prefer to contact a member of the Help us Discover team about this trial and other similar trials, please email helpusdiscover@yale.edu or call 877.978.8343

  • Last Updated
    07/27/2021
  • Study HIC
    #2000021054