Search Results < Clinical Trials at Yale

32 results

News
Clinical Trial Builds Upon Yale Studies to Provide Proof-of-Concept that Subtype-specific Sodium Channel Blockers can Reduce Pain in Humans
Pain is a pervasive symptom encountered by physicians worldwide and a longstanding medical challenge, particularly against the backdrop of the opioid crisis.
3 Aug 2023
News
New Research Shows How Sleep Apnea Might Affect Heart Health
Henry Yaggi, MD, MPH, professor of medicine (pulmonary, critical care and sleep medicine), discusses new research that shows people with obstructive sleep apnea have an increased risk of cardiovascular disease.
Source: Health
3 Aug 2023
News
Biological Factors Modulate Eating Disorder Risk in Early Adolescents
New Yale research reveals associations among genetics, brain structure, and eating disorder risk can be observed in children as young as 9 years old.
Source: YaleNews
2 Aug 2023
News
Women With Endometriosis Also Genetically Predisposed to Depression, Anxiety, and Eating Disorders
The largest epidemiological study to date on the psychiatric factors that can accompany endometriosis has demonstrated that depression, anxiety, and eating disorders are not only a result of the chronic pain endometriosis generates, but also have their own underlying genetic mechanisms.
1 Aug 2023
News
Dr. Chernova Researches How B Cells Survive in the Kidney
The 2023 Iva Dostanic, MD, PhD, Physician-Scientist Trainee Award Medical Grand Rounds (MGR) lecture was presented by Irene Chernova, MD, PhD, assistant professor of medicine (nephrology), on Thursday, June 22, 2023.
12 Jul 2023
News
Long term Structural and Functional Neural Changes Following a Single Infusion of Ketamine in PTSD
Or Duek, PhD, assistant professor adjunct of psychiatry, and Ilan Harpaz-Rotem, PhD, professor of psychiatry and of psychology, are first and senior authors, respectively of a study published in Neuropsychopharmacology that tests the potential of a single infusion of ketamine, followed by brief exposure therapy, to enhance post-retrieval extinction of post-traumatic stress disorder trauma memories.
Source: Neuropsychopharmacology
21 Jun 2023
News
Diminished Brain Response to Nutrients Observed in People With Obesity
In a new study led by Mireille Serlie, MD, PhD, professor of medicine (endocrinology), researchers found that while the detection of nutrients in the stomach does induce brain activity changes in lean people, such brain responses are largely diminished in people with obesity.
Source: Yale News
16 Jun 2023
News
Cost-Effectiveness of Equity-Enhancing Gene Therapy in Sickle Cell Disease
With his new study, George Goshua, MD, MSc, assistant professor of medicine (hematology), hopes to make clear that we cannot continue to ignore the importance of quantifying value and equity in our decision-making.
30 May 2023
News
Ketamine Shows Promise for Hard-to-Treat Depression in New Study
Research this week presents the most robust evidence to date that ketamine is at least as effective as electroconvulsive therapy for patients with treatment-resistant depression who do not have psychosis.
Source: The New York Times
26 May 2023
News
How the Stigma of Herpes Harms Patients and Stymies Research for a Cure
Scientists have done promising work on taming herpes simplex viruses, but while infected people continue to suffer, Yale experts say funding for vaccine research and development has been lacking.
25 May 2023
News
Changing the Lives of Patients With Alopecia and Vitiligo
Progress was slow for several years, but a Yale physician-scientist finally saw the FDA approve drugs for which he had advocated to treat the debilitating conditions alopecia and vitiligo.
17 May 2023
News
‘We’re failing to make progress’: Studies show ongoing toll of premature Black deaths
Black Americans have suffered 1.63 million excess deaths and lost more than 80 million years of life compared to white Americans, according to a new analysis.
Source: STAT
16 May 2023
News
Rehospitalization more common for young women vs. men after heart attack
Young women who survive an acute MI are more likely to be readmitted during the year after discharge compared with similarly aged men, researchers reported.
Source: Healio
1 May 2023
News
Yale Researcher Awarded $40 Million to Lead New VA Study to Evaluate Esketamine for Treatment Resistant Depression
Somaia Mohamed, MD, PhD, associate professor of psychiatry, is lead co-investigator of a Department of Veterans Affairs (VA) study that has been awarded $40 million to evaluate the effectiveness of a novel antidepressant medicine, esketamine, for veterans and others with treatment resistant depression (TRD).
27 Apr 2023
News
Study Uncovers Biological Mechanism Behind Loss of Smell in Parkinson’s Patients
In a new study published in Journal of Neuroscience, researchers uncover the biological mechanism behind loss of smell in Parkinson's patients.
19 Apr 2023
News
Use of Buprenorphine to Treat Fentanyl Distress Produces Few Adverse Reactions
A new study across 28 emergency departments (EDs) with a high prevalence of fentanyl use has found that the incidence of a severe withdrawal reaction after use of buprenorphine is rare—less than one percent, a result that pleasantly surprised the researchers.
13 Apr 2023
News
How ‘Weathering’ Contributes to Racial Health Disparities
Marcella Nunez-Smith, MD, MHS, associate dean for health equity research and C.N.H. Long Professor of Internal Medicine (General Medicine), talks about how weathering, a form of chronic stress, provides a framework for understanding health inequities.
Source: The New York Times
12 Apr 2023
News
Yale Team Uncovers Promising New Therapeutic for Anorexia Nervosa
Researchers found that a small synthetic molecule called Bobcat339 significantly weakened anorexia nervosa—as well as associated anxiety and depressive-like behaviors—in a mouse model, with few side effects.
10 Apr 2023
News
Study: Daily Consumption of a High-Fat, High-Sugar Snack Alters Reward Circuits in Brain
Snacks high in sugar and fat are great for an occasional treat, but when enjoyed daily for several weeks they can rewire the brain and trigger a shift in eating preferences away from low-fat food, according to a new study in Cell Metabolism.
22 Mar 2023
News
YCCI Interim Director, Dr. David Coleman, recipient of the 2023 Larry Zaroff Man of Good Conscious Award
New Interim Director of YCCI David Coleman, MD, Research Professor of Medicine, Emeritus Professor, Yale School of Medicine, is a recipient of the 2023 Larry Zaroff Man of Good Conscious Award from the American Medical Women’s Association. The Association presents this award annually to a man who has been a champion and supporter of women in medicine.
5 Mar 2023