Scientists find clues to mystery of Williams Syndrome’s peculiar symptoms
Patients with Williams Syndrome often are extremely social and possess a remarkable affinity and talent for music. They also experience life-threatening cardiovascular problems and developmental disabilities. The mystery is what happens during development to cause such peculiar symptoms.
Study points to potential personalized approach to treating lupus
In individuals with lupus, immune cells attack the body’s own tissue and organs as if they are enemy invaders. A new Yale-led study describes how a protein found in common bacteria triggers that auto-immune response. The finding opens the door to future therapies targeting the bacteria rather than the immune system, the researchers said.
Cellular garbage collectors implicated in development of Alzheimer’s
Lysosomes are cellular sanitation engineers that help clean up and recycle internal debris no longer needed by cells. So why do researchers find so many lysosomes within the neuronal projections surrounding amyloid plaques, a hallmark of Alzheimer’s Disease brain pathology?
Good cellular neighbors combat incipient cancers
Scientists have spent decades studying the nature of tumor cells, but few have looked to see what was happening in the surrounding tissue. When Yale researchers took a closer look at skin cells, they discovered the unaffected neighbor cells are not helplessly awaiting invasion of cancer cells but acting like cellular police, actively correcting tissue flaws created by their aberrant neighbors, the investigators report Aug. 2 in the journal Nature.
Bio Haven: How Yale and New Haven are building a future together
New Haven’s biotech community has seen fits and starts, but today it is achieving critical mass. Upwards of 50 biotech and medical device companies employ more than 5,000 people in greater New Haven. Yale School of Medicine has been instrumental in the communty's growth.
How Medical Research Is Boosting Connecticut’s Economy
Jason Thomson’s personal journey illustrates an economic shift in Connecticut. After he was laid off by Pfizer six years ago, he found a great job at the Yale Stem Cell Center. The center's groundbreaking research is leading to clinical advances and helping to foster a bioscience startup industry.
Yale researchers using new approaches to study cancer, seek treatments
Researchers at Yale University’s West Campus are teaming up to go deep within cells that make up a malignant tumor, looking for ways to fight cancer on the molecular level. At that scale, it’s important to look at systems that molecules make up, rather than looking at them individually, say researchers at the Systems Biology Institute and the Cancer Biology Institute.Source: The New Haven Register
CaSB@Yale launches with $9.5M federal grant to battle deadliest cancers
Yale University researchers across a spectrum of disciplines are coming together to fight some of the deadliest forms of cancer with a novel approach that has gained support from the National Cancer Institute (NCI) of the National Institutes of Health (NIH).
Yale scientists capture cell ‘crosstalk’ during blood vessel development
The blood vessels that carry oxygen and nutrients throughout the body develop through a complex process of reactions — or crosstalk — between cells that is regulated by cell-specific gene expression. In a recent study published in Nature Communications, a Yale-led team of researchers identified a key mediator of this crosstalk and determined how it affects the formation of new blood vessels.Source: Yale News