Small: Yale study may help resolve bitter debate over low-cal sweeteners
Several studies in recent years have reported that low-calorie sweeteners in foods and beverages disrupt the human metabolism, promoting the development of diabetes and obesity. But other studies have found that consuming low-calorie drinks and food has little impact on metabolism and might actually aid in weight loss. A new study by Yale researchers published March 3 in the journal Cell Metabolism may help reconcile these conflicting findings.
How obesity drives colon cancer in mice
Obesity, which is on the rise worldwide, has been linked to colon cancer but the mechanism has been a mystery. In a new study, Yale researchers and their co-authors have uncovered how obesity drives tumor growth in mice, revealing potential strategies to combat the disease.
Human insulin as safe and effective to treat type 2 diabetes as costlier insulin analogs
Patients with Type 2 diabetes who were treated with the newer generation of insulin analog drugs did not have substantially better outcomes than those treated with less costly human insulin, according to a study by Yale School of Medicine researchers and colleagues at Kaiser Permanente.
Prevalence of eating disorders taken from largest sample in the United States
Carlos Grilo, PhD, Professor of Psychiatry and of Psychology and Director of the Program for Obesity Weight and Eating Research (POWER) at Yale, is the senior author of a new study published in Biological Psychiatry that revises the outdated estimates of the prevalence of eating disorders in the United States.
Study illuminates tiny RNA’s role in heart disease, obesity
A tiny RNA molecule plays a big role in the development of two diseases affecting billions of people worldwide: heart disease and obesity. Yale researchers have found that by disrupting this microRNA in key tissues, they can reduce plaque buildup in arteries while avoiding unintended effects.
Lower brain glucose levels found in people with obesity, type 2 diabetes
Glucose levels are reduced in the brains of individuals with obesity and type 2 diabetes compared to lean individuals, according to a new Yale study. The finding might explain disordered eating behavior — and even a higher risk of Alzheimer’s disease — among obese and diabetic individuals, the researchers said.
American Stroke Association honors 10 scientists, researchers for exemplary work
Jennnifer Dearborn-Tomazos, M.D., M.P.H., was honored by The American Stroke Association (ASA) recently at its International Stroke Conference in Houston for her research study that diet at midlife is not associated with cognitive decline.Source: cardiovascularbusiness.com
Does where you live affect what you weigh?
In a new study, researchers at the Yale Global Health Leadership Institute (GHLI) explored community-level factors that may be associated with reduced adult obesity rates in counties within states that have a high adult obesity rate. Such geographic variation raises questions about the influence of community and regional factors on obesity, said the researchers.
Yale investigators join alliance to advance research on obesity and diabetes
Yale researchers have partnered with investigators at leading research institutions in Connecticut, and with a prestigious counterpart in Israel, to fill a research void in the field of metabolic diseases, which affect billions of people worldwide.
Research note: The immune system-body weight connection
A new Yale study, led by professor of immunobiology and Howard Hughes Medical Institute investigator Akiko Iwasaki, identified a population of macrophages, a type of white blood cell, that resides within the fat tissue to maintain body weight.