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Older Adults and Alzheimer's Studies Enrolling at Yale

March 01, 2024

Be Part of Clinical Research at Yale

Brain Imaging Research Study

If you are 65+ years of age, you may be eligible to participate in a brain imaging (MRI: magnetic resonance imaging) research study. We are specifically seeking participants with subjective cognitive/memory complaint (if you experience any problems with memory or thinking), but healthy participants without such changes are welcomed too.

No medications or radioactivity.

Compensation up to $130.

If you are interested in participating, or if you have any questions, please call 203-974-7891 or email: shefali.chaudhary@yale.edu and mention "aging study".

Sponsored by The National Institute on Aging (NIA); HIC# 2000028664


Are you aged 50 or older and began using cannabis or medical marijuana later in life?

Participate in a Yale research study investigating the effects of cannabis on the brain. All calls are confidential.

Compensation up to $625.

Please call 203-626-1105.

Sponsored by The National Institute on Drug Abuse; HIC# 2000032183


All of Us Research Program

The All of Us Research Program is a large research program. The goal is to help researchers understand more about why people get sick or stay healthy by creating a biorepository.

People who join will give us information about their health, habits, and what it’s like where they live. By looking for patterns, researchers may learn more about what affects people’s health. If you decide to join All of Us, we will ask you to share different kinds of information like your name and where you live, questions about your family, home, and work. If you have an Electronic Medical Record, we may ask you for access. We will also ask you to come in for physical measurements like, height, weight, hip and waist circumference, and blood pressure, and heart rate. We will also ask you to provide blood and urine samples, or saliva.

Total Compensation: $25

If interested, please contact: allofus@yale.edu or call 203-785-5977.

Sponsored by University of California, San Diego; HIC# 2000034651


Have you had a stroke and have high blood pressure?

We are looking for 8-10 patients with stroke and high blood pressure who are interested in serving on a Patient Advisory Board that will help guide efforts to improve blood pressure control among patients with stroke. Caregivers are also invited to participate. Please reach out if you are interested and if you would like additional information.

Bank of America pre-paid debit card of $50 per meeting.

To learn more or to see if you are eligible to participate, please contact us at (203) 215-9832 or email: Rachel.Forman@yale.edu

Sponsored by: Merck Sharp & Dohme LLC; National Institute of Allergy and Infectious Diseases (NIAID); National Institute of Mental Health (NIMH); Yale University School of Medicine; HIC# 1502015318


Cognitive Training Study in Parkinson’s Disease

If you are a Parkinson’s disease patient who is 40+ years of age, fluent in English, able to pass an MRI metal screening, and are not claustrophobic, you may be eligible to participate in a free and confidential trial that will help us understand the potential mental and brain benefits of cognitive training in Parkinson’s disease. The study involves 6-week training and in-person visits that will include neurological and cognitive assessments, and MRI scans.

Compensation up to $650.

To learn more or see if you are eligible to participate, email: cognitive@yale.edu or call (203)785-2185.

Sponsored by National Institute of Neurological Disorders and Stroke (NINDS); HIC #2000033352


Do you act out your dreams?

Neuro-immune Interactome in Parkinson's Disease

If you are over 40 years of age and do act out your dreams by kicking or punching out along with talking and/or yelling, you may have REM behavior disorder. REM Sleep Behavior Disturbance (RBD) is a sleep problem which may (or may not) be an early sign of Parkinson’s Disease (PD) or other neurological problems. The purpose of this research study is to determine whether or not RBD is associated with an immune process initiated in the gut, and to identify the earliest immunological changes in people at risk for developing PD. Your participation will require one or two phone or online interviews, and two to three in-person visits to research facilities at Yale New Haven Hospital, then yearly visits thereafter.

Compensation up to $500.

To learn more or see if you are eligible to participate, contact Kara Mead, Yale Sleep Medicine and Neurology, at kara.mead@yale.edu or call (203) 785-2285.

Sponsored by Michael J. Fox Foundation and Yale University School of Medicine; HIC#: 2000029032


Do you have Parkinson’s disease and symptoms of depression?

Depression can have a real impact on quality of life. But right now treatments for depression in PD are inadequate. We believe that the drug ketamine could reduce depression and possibly target other symptoms of PD.

The trial will involve receiving either ketamine or placebo twice per week for 3 weeks. You will also have the option to take part in brain imaging before and after the treatment.

You will be reimbursed up to $2000 for your time.

Call or Text: (475) 287-9521 E-mail: ketaminepd@yale.edu. Click here for more information on this trial.

Sponsored by the Michael J. Fox Foundation; HIC #2000030394


Network Integrity in Neurodegenerative Disease

If you are 40 to 90 years of age and have been diagnosed with posterior cortical atrophy, logopenic aphasia, dementia with Lewy bodies, frontotemporal dementia, mild cognitive impairment, or Alzheimer’s disease, you may be eligible to participate in this research study. The purpose of this research study is to see how less common forms of Alzheimer’s disease affect brain networks, memory, and thinking. Visits involve medical screening, cognitive tests, and MRI imaging.

Compensation is up to $225.

To learn more or see if you are eligible to participate, email fredericks.lab@yale.edu

Sponsored by Network Integrity in Neurodegenerative Disease HIC# 2000032137

Submitted by Lisa Brophy on February 08, 2024