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Adult Mental Health Studies Enrolling at Yale

March 01, 2024

Be Part of Clinical Research at Yale

Have you experienced a life-threatening event?

If you are between the ages of 18-60 and have experienced a traumatic or life-threatening event, you may be eligible to participate in a research study examining brain activity in individuals with PTSD. Study visits involve a psychological screening over Zoom to determine eligibility, a 90-minute fMRI scan, and a 90-minute MEG scan. This is not a treatment study, but your participation will play an important role in helping to advance treatment.

Participants will receive $50 for the psychological screen, $100 for the fMRI, and $150 for the MEG, as well as travel reimbursement.

If you are interested in learning more, please email us at ptsd.stress.lab@yale.edu or call/text (203) 936-9322.

Sponsored by Yale University School of Medicine, HIC# 2000025892


Do you have Post-Traumatic Stress Disorder (PTSD) and are interested in a new, rapid 7 day treatment?

Combining Neurobiology and New Learning (Ketamine/midazolam combined with psychotherapy) for a Potential Rapid Treatment for PTSD

We are currently recruiting participants with PTSD who are 21 to 70 years old for a study that involves a week long treatment for those with PTSD.

Compensation up to $900.

If you are interested in learning more, please email us at ptsd.stress.lab@yale.edu or call/text (203) 936-9322.

Sponsored by National Institutes of Health (NIH); National Center for PTSD (NCPTSD); Yale University School of Medicine; HIC# 1509016530


Do you have trichotillomania?

Efficacy of Valbenazine for the Treatment of Trichotillomania in Adults

If you are an adult with trichotillomania, you may be eligible to participate in a research study run by the Yale School of Medicine. This study will examine the efficacy of Valbenazine for the treatment of trichotillomania. Valbenazine is a dopamine-depleting agent that is currently FDA-approved for tardive dyskinesia and has a relatively safe side-effect profile in initial trials.

While enrolled in the trial, you will receive regular psychiatric and medical assessments of symptoms at no cost. Additionally, you will receive a stipend of up to $590 over the course of 26 weeks for your participation.

If you are interested in the trial or wish to learn more, please do not hesitate to contact us by phone at 203-737-4809 or email at blochresearch@yale.edu if you have any questions about the trial.

Sponsored by Neurocrine Biosciences, Inc.; HIC# 2000034993


Are you experiencing suicidal thoughts but NOT planning to act on them? Have you tried antidepressants before without much success?

Help us understand the effects of the rapid antidepressant ketamine on the brain and earn up to $435 for your time.

For more information and to see if you are eligible to participate, contact (203)692-9263 or email nempro.lab@yale.edu.

Sponsored by American Foundation for Suicide Prevention, HIC# 2000033608


Are you Depressed?

Have you tried antidepressants before without much success? Help us understand the effects of the rapid antidepressant ketamine on the brain and earn up to $670 for your time.

For more information and to see if you are eligible to participate, contact (203)692-9263 or email nempro.lab@yale.edu.

Sponsored by National Institutes of Mental Health, HIC# 200021345


Concerned about eating or overeating?

If you are between 21 and 50 years old with binge-eating disorder, you may be eligible for a brain-imaging study. Study visits involve in-person screening visits to determine eligibility, a 30-minute MRI scan, and a 90-minute PET scan. This is not a treatment study.

Compensation up to $400.

If you are interested in participating, or if you have any questions, please contact our study coordinators, Adam Stryjewski (adam.stryjewski@yale.edu; 203-535-4424) or Marcella Mignosa (marcella.mignosa@yale.edu; 203-903-7795) and mention “binge-eating study.”

Sponsored by National Institute of Mental Health (NIMH); HIC#2000034271


Are you aged 12-30 and noticing a recent change in your thinking, behavior, or experiences?

Pro-Net Study

If you're between the ages of 12 and 30 and have recently experienced changes in your thinking, behavior, or experiences, you may qualify for this study. These changes include confusion between reality and imagination, feeling a lack of control over your thoughts or ideas, being suspicious or paranoid, experiencing unreal sensations like hearing sounds or seeing things that aren't there, and having difficulty communicating clearly.

Participants in this study will undergo an initial screening visit, 2 MRI scans, and 2 sets of blood work. Additionally, they will be asked questions about their experiences and emotional well-being.

Total compensation of up to $1000 is provided.

To inquire further or determine eligibility for participation, please contact us at 203-200-8997 or email pronetstudy@yale.edu.

Sponsored by National Institute of Mental Health (NIMH); HIC# 2000029159


Have you experienced a traumatic event?

If you are between the ages of 18 to 45, you can help in advancing research about trauma and its impacts. Compensation will be provided.

If you’re interested, please fill out our screening questionnaire to see if you are eligible: https://redcap.research.yale.edu/surveys/?s=4F4TNRX473PH97NX

Sponsored by the National Institute of Mental Health and the Yale University School of Medicine; HIC# 2000026215


Have you been diagnosed with a psychotic-spectrum disorder? Do you experience auditory hallucinations?

If you are between the ages of 18 and 65, are right-handed, and speak English, you could help advance psychiatric research by participating in our brain imaging study. Auditory hallucinations are among the most distressing aspects of psychotic illness, and between 10 and 30% of people with hallucinations do not respond to antipsychotic medications. Help us take the first step toward individualized treatment approaches to hallucinations.

Compensation up to $400 for your participation.

For more information, and see if you are eligible to participate, please contact us: Text or call: 203-441-7213 email: powerslab3@gmail.com.

Sponsored by Burroughs Wellcome Fund; National Institute of Mental Health (NIMH); Yale University School of Medicine;HIC# 2000024774


Do you act out your dreams?

Neuro-immune Interactome in Parkinson's Disease

If you are over 40 years of age and do act out your dreams by kicking or punching out along with talking and/or yelling, you may have REM behavior disorder. REM Sleep Behavior Disturbance (RBD) is a sleep problem which may (or may not) be an early sign of Parkinson’s Disease (PD) or other neurological problems. The purpose of this research study is to determine whether or not RBD is associated with an immune process initiated in the gut, and to identify the earliest immunological changes in people at risk for developing PD. Your participation will require one or two phone or online interviews, and two to three in-person visits to research facilities at Yale New Haven Hospital, then yearly visits thereafter.

Compensation up to $500.

To learn more or see if you are eligible to participate, contact Kara Mead, Yale Sleep Medicine and Neurology, at kara.mead@yale.edu or call (203) 785-2285.

Sponsored by Michael J. Fox Foundation and Yale University School of Medicine; HIC#: 2000029032


Do you have Parkinson’s disease and symptoms of depression?

Depression can have a real impact on quality of life. But right now treatments for depression in PD are inadequate. We believe that the drug ketamine could reduce depression and possibly target other symptoms of PD.

The trial will involve receiving either ketamine or placebo twice per week for 3 weeks. You will also have the option to take part in brain imaging before and after the treatment.

You will be reimbursed up to $2000 for your time.

Contact us to find out more. Call or Text: (475) 287-9521 E-mail: ketaminepd@yale.edu. Click here for more information on this trial.

Sponsored by National Institute of Neurological Disorders and Stroke (NINDS); HIC #2000033352


Are you a first-time expectant mother or father? Help us learn about changes across the transition to parenthood.

If you are currently expecting a child for the first time, you and/or your partner may be eligible to participate in a research study focused on understanding more about emotions, the brain, and behavior in new parents before and after the baby is born.

This study involves: 1) a brief online study visit during the third trimester of pregnancy, and 2) one in- person lab visit with you and your infant around 2-4 months after delivery. You would complete surveys, tasks, and non-invasive measures of brain activity as part of the study.

Compensation for this study is $100 ($20 for pregnancy visit, $80 for after-delivery visit) in the form of gift cards. If your partner is also participating, you would each be separately compensated $100. Compensation for parking/travel is also available.

If you are interested in participating in the Emotions, Brain, and Behavior (EBB) Study for new parents, please email us at thebabl@yale.edu or call/text 475-500-5828.

Sponsored by American Psychological Foundation; HIC# 2000033554

Submitted by Lisa Brophy on February 07, 2024