Clinical trial looking for healthy volunteers
If you are 18 to 40 years old and are in good health, you may be eligible to participate in a free and confidential research study investigating how our immune system responds to flu vaccine administered into the skin.
If you enroll, you would be asked to come to the Yale Center for Clinical Investigation (YCCI) clinic located at 2 Church Street S #401, New Haven, CT, for 9-10 required visits. You will be randomly assigned to receive the flu vaccine or a saline (water) control. The visits include asking questions about your medical history and list of medications you are taking, measuring vital signs, a physical exam, blood tests including genetic testing, small skin biopsies, nasal and skin swabs. Drs. Andrew Johnston and Inci Yildirim are leading the study.
Compensation up to $600.
If you are interested in participating in this study, please contact IDVaxTeam@yale.edu.
Sponsored by Yale University School of Medicine; HIC# 2000035891
Healthy adults needed
If you are 18 years of age or older and have no major ongoing health problems, you may be eligible to participate in a research study examining the immune response to vaccines among healthy and immune compromised people. Study participants will have a “sham vaccine” (injection of small volume of saline) in one arm. Approximately 4 days later, you will have skin biopsies from both arms. Each visit could take 15-20 minutes.
Compensation of $100 is provided.
To learn more or see if you are eligible to participate, please email MSResearch@yale.edu or Isabella.Cruz@yale.edu.
Sponsored by National Institute of Allergy and Infectious Diseases (NIAID); Robert Leet and Clara Guthrie Patterson Trust; HIC# 2000029889
Curious about how your daily emotions are linked with social interpretations?
If you are between the ages 18 to 65, and have access to a smartphone, you may qualify for a research study on emotions and thoughts.
Participation includes an in-person visit (with an interview and a computer task), followed by two-week daily online surveys (5-10 min).
You will receive $45 compensation after completing the online surveys.
For more information email Yale’s Affect Regulation & Cognition Lab at yale.arc.lab@gmail.com or text 475-329-9058.
Sponsored by the Yale University School of Medicine; HIC#: 2000031726
Females aged 18-45 years old needed for study on decision-making and eating behavior
We are looking for women with a Body Mass Index (BMI) between 18.5 and 24.9 kg/m2 and no history of mental health conditions, brain injury, or neurological conditions, to participate in a brain imaging study. You will complete two visits to the Yale University Magnetic Resonance Research Center.
At the screening visit we will collect a blood sample and ask you some questions about your health history. The study visit will involve questionnaires, computer tasks, an MRI scan, and additional blood sampling. Then we will ask you to complete follow-up surveys at home.
You will be compensated up to $240 for your time.
For more information contact Maggie Westwater at Margaret.westwater@yale.edu or call 203-215-7611.
Sponsored by the Yale University School of Medicine; HIC#: 2000034480
¿Hablas español y nunca ha tenido cáncer?
Se necesitan participantes que hablen español.
El propósito de este estudio de investigación es validar la Escala de Estigma del Cáncer (CASS) en español para determinar si funciona como herramienta en la población de hablantes de español de la misma manera que en la población de hablantes de inglés. Al hacerlo, ayudará a determinar si es una herramienta factible y confiable para evaluar los niveles de estigma del cáncer en las poblaciones que hablan español.
Los participantes pueden entrar a un sorteo para ganar una tarjeta de regalo de $50 al completar la encuesta.
Los participantes elegibles deben:
1. Ser mayores de 18 años
2. Tener habilidades para leer en español
3. Nunca haber sido diagnosticados con cáncer
El procedimiento implica completar un cuestionario a través del enlace proporcionado, lo cual tomará aproximadamente 10 minutos. Sus respuestas serán anónimas y no estarán vinculadas a ninguna información identificativa.
Si estás interesado/a y cumples con los criterios, el enlace a la encuesta está aquí:
https://yalesurvey.ca1.qualtrics.com/jfe/form/SV_1FT3F90EUUoqpKe
Si tienes preguntas, por favor contacta al equipo de investigación al 203-785-5545.
Patrocinado por la Facultad de Medicina de la Universidad de Yale; HIC# 2000035196
Are you aged 50+ and had 1 or 2 non-cancerous (benign) growths of tissue (polyps) removed during a colonoscopy?
FORTE: A Colorectal Cancer Prevention Trial
If you have had 1 or 2 non-cancerous (benign) growths of tissue (polyps) removed during a colonoscopy and are at least 50 years old, you may be eligible to participate in a confidential research study. The study is being conducted to determine the best timing for a repeat colonoscopy for patients who have had 1 or 2 benign polyps removed during an initial colonoscopy.
If you enroll, you would have either a colonoscopy at 10 years or at 5 years and at 10 years after your colonoscopy that found 1 or 2 small polyps. You would be asked to complete questionnaires and provide samples for future research. At least once a year during your participation, we would contact you to inquire about your health, results of colonoscopy exams, or other medical information. Your participation would end after you undergo the colonoscopy at 10 years. You may be contacted for up to 30 years after you join the study.
You will receive a stipend for each sample collection completed.
To learn more or see if you are eligible to participate, please email our Help us Discover team at helpusdiscover@yale.edu.
Sponsored by the NRG Oncology Foundation with public funding from the National Cancer Institute (NCI); HIC# 2000034174
Planning to update your COVID vaccine?
Yale researchers are studying the immune response to COVID vaccinations among healthy and immune suppressed individuals. If you are planning to update your vaccine, you may qualify for a research study.
Qualifying participants should be:
- Age 18 or older
- Planning to update their COVID19 vaccination within the next 90 days
EITHER:
- Healthy (no history of immune problems and not taking any immune suppressing medicine)
- Taking a B-cell depleting medicine (e.g. rituximab, ocrelizumab, ofatumumab) to treat an autoimmune disease
- Taking glatiramer or interferon-type medication to treat an autoimmune disease
Participants in this research project will have a fine needle aspiration and/or biopsy of lymph nodes in their armpit before and at several timepoints after vaccination. Ultrasounds will be performed before these procedures to visualize the lymph nodes. Blood will also be collected. There would be 4-6 study visits over about 10 weeks.
Compensation of up to $750 is available.
If you are interested, please complete the pre-screening survey at https://redcap.link/9md3047j or email MSResearch@yale.edu.
Sponsored by Hoffmann (F) - La Roche, Ltd; National Institute of Allergy and Infectious Diseases (NIAID); Robert Leet and Clara Guthrie Patterson Trust; Yale University School of Medicine.; HIC#2000032631
All of Us Research Program
The All of Us Research Program is a large research program. The goal is to help researchers understand more about why people get sick or stay healthy by creating a biorepository.
People who join will give us information about their health, habits, and what it’s like where they live. By looking for patterns, researchers may learn more about what affects people’s health. If you decide to join All of Us, we will ask you to share different kinds of information like your name and where you live, questions about your family, home, and work. If you have an Electronic Medical Record, we may ask you for access. We will also ask you to come in for physical measurements like, height, weight, hip and waist circumference, and blood pressure, and heart rate. We will also ask you to provide blood and urine samples, or saliva.
Total Compensation: $25
If interested, please contact: allofus@yale.edu , 203-785-5977
Sponsored by University of California, San Diego; HIC 2000034651
Are you a healthy young man between the ages of 18-25?
Connectivity While Coming of Age Study
Are you a healthy young man between the ages of 18 and 25? If so, you may be eligible to participate in a longitudinal MRI study looking at short-term changes in the brain.
This study involves 5 in-person visits across 6 months, including an initial screening visit and 4 MRI brain scans. You will also be asked to answer a few brief questions about your substance use daily and complete follow-up assessments at 3- and 6-months.
Total compensation up to $708.
To learn more or to see if you are eligible to participate, please contact us at 203-307-5141 or email: brain.research@yale.edu
Sponsored by National Institute on Drug Abuse (NIDA); HIC# 2000028368
Brain Connections & HIV Study
You can play an important role in research by volunteering for a free and confidential study Yale is conducting to learn about changes in the brain. Our brains change as we age. Our brains also change with certain health conditions such as dementia. We are interested in looking at whether or not people with certain infectious diseases such as HIV have similar changes by looking at two different brain scans. Our hope is that this study leads to improved treatment for individuals with cognitive impairment living with HIV. Your privacy is of the upmost importance to us. Study procedures include: blood draws, a lumbar puncture (optional), EKG, MRI, PET scan, complete a set of memory tasks, health surveys and willingness to co-enroll in our Biobank study, HIC# 1502015318 (with separate compensation provided).
We are enrolling participants who are HIV negative (do not have HIV) OR living with HIV.
Compensation up to $1150.00 - $1700.00 for study completion (over 2 years).
If interested, contact Allison Nelson at 475-434-4324 or email: NeuroID@yale.edu for more information.
Sponsored by National Institute of Mental Health/NIH/DHHS; HIC# 2000033582 & HIC#150215318
Are you a first-time expectant mother or father? Help us learn about changes across the transition to parenthood!
If you are currently expecting a child for the first time, you and/or your partner may be eligible to participate in a research study focused on understanding more about emotions, the brain, and behavior in new parents before and after the baby is born. This study involves: 1) a brief online study visit during the third trimester of pregnancy, and 2) one in- person lab visit with you and your infant around 2-4 months after delivery. You would complete surveys, tasks, and non-invasive measures of brain activity as part of the study.
Compensation for this study is $100 ($20 for pregnancy visit, $80 for after-delivery visit) in the form of gift cards. If your partner is also participating, you would each be separately compensated $100. Compensation for parking/travel is also available.
If you are interested in participating in the Emotions, Brain, and Behavior (EBB) Study for new parents, please email us at thebabl@yale.edu or call/text 475-500-5828.
Sponsored by American Psychological Foundation; HIC # 2000033554
Help us understand how endometriosis impacts long-term cardiovascular health
If you are a woman (18 – 45 years old) with or without endometriosis, you may be eligible to participate in a free and confidential study designed to look at how estrogen may affect cardiovascular health. Individuals currently using hormonal birth control are not eligible.
Minority women are encouraged to participate as it is important to study different groups of people to understand what treatments work best for most women.
Participation requires three in-person visits to the John B. Pierce Lab, including one screening visit (~1 hour) and two experimental visits (~5 hours each).
Compensation up to $380.
To learn more or to see if you are eligible to participate, please email Abby at endoresearch@jbpierce.org.
Sponsored by the National Institutes of Health, National Heart Lung, and Blood Institute; HIC#: 2000022193
Are you a healthy adult age 18-45?
Decision-making study
This study is examining how people learn and make decisions and involves three 2-hour visits at our lab in New Haven. This study is noninvasive, and no medications are involved.
- First Visit: Will involve a 1-1.5 hour fMRI brain scan, which is a non-invasive method of studying the brain. During the scan, you will complete a computer task in which you'll make a series of decisions about money.
- Second Visit: Will involve a 1-1.5 hour fMRI brain scan, which is a non-invasive method of studying the brain. During the scan, you will complete another computer task.
- Third Visit: You will fill out some personal evaluation questionnaires and work on some problem-solving tasks.
Participants will receive $250 - $490 for completing the study, as well as reimbursement for travel expenses.
To learn more or see if you are eligible, please contact the Decision Neuroscience Lab at Yale School of Medicine at (475) 414-6484, or email decision@yale.edu. Please mention the Decision-making fMRI study and include your name and phone number in your call or email.
Sponsored by Yale University School of Medicine; HIC#: 0910005795
TMS study for adults with autism or typical development
This study will evaluate the effects of repetitive Transcranial Magnetic Stimulation (rTMS), a type of noninvasive brain stimulation, on the social brain. TMS is a therapy that has been approved for depression and obsessive-compulsive disorder and we are looking to see if it can also help those with ASD. This method uses magnetic waves administered in a train of pulses to influence brain activity. A participant visit includes a baseline assessment of neuropsychological, cognitive and behavioral function and an EEG and eye-tracking session to measure visual and social responses before and after TMS.
Participation requires 2 visits and participants must be between the ages of 18-40 years old.
*Please note that we are not currently enrolling females with typical development at this time
Compensation is $100 per visit to participate.
To learn more or see if you are eligible to participate, please call our team at 203-737-3439 or email autism@yale.edu.
Sponsored by Department of the Army; HIC#2000030576
Have you experienced a traumatic event?
If you are between the ages of 18 to 45, you can help in advancing research about trauma and its impacts. Compensation will be provided.
If you’re interested, please fill out our screening questionnaire to see if you are eligible: https://redcap.research.yale.edu/surveys/?s=4F4TNRX473PH97NX
Sponsored by the National Institute of Mental Health and the Yale University School of Medicine; HIC# 2000026215
Are you 18+ with a close family member (parent, sibling, or child) with multiple sclerosis?
DREAM study (Detection Research on Early Asymptomatic MS)
Yale researchers are looking for participants in an ongoing research study. Participation includes one in-person visit with a blood draw, and questionnaires, which can be completed online. Additional blood draws and procedures are optional.
You may be eligible to participate if you:
- Have a close family member (parent, sibling, or child) with multiple sclerosis
- Are age 18 or older
Prescreening survey link is here: https://redcap.link/r057eydl
Sponsored by Hoffmann (F) - La Roche, Ltd; Yale University School of Medicine; HIC# 2000032952
Covid Mind Study
We are looking for healthy adults (18 yers and older) to participate in our study on Post-Covid-19 Neurological Conditions. Earn up to $150 for participating in a 5-hour visit including a blood draw, lumbar puncture (spinal tap), surveys, and neuropsychological testing.
If you are interested, please contact us at 475-434-4324 or neuroid@yale.edu.
Sponsored by Merck Sharp & Dohme LLC; National Institute of Allergy and Infectious Diseases (NIAID); National Institute of Mental Health (NIMH); Yale University School of Medicine; HIC# 1502015318
Do you act out your dreams?
Neuro-immune Interactome in Parkinson's Disease
If you are over 40 years of age and do act out your dreams by kicking or punching out along with talking and/or yelling, you may have REM behavior disorder. REM Sleep Behavior Disturbance (RBD) is a sleep problem which may (or may not) be an early sign of Parkinson’s Disease (PD) or other neurological problems. The purpose of this research study is to determine whether or not RBD is associated with an immune process initiated in the gut, and to identify the earliest immunological changes in people at risk for developing PD. Your participation will require one or two phone or online interviews, and two to three in-person visits to research facilities at Yale New Haven Hospital, then yearly visits thereafter.
We are recruiting healthy volunteers too.
Compensation up to $500.
To learn more or see if you are eligible to participate, contact Kara Mead, Yale Sleep Medicine and Neurology, at kara.mead@yale.edu or call (203) 785-2285.
Sponsored by Michael J. Fox Foundation and Yale University School of Medicine; HIC#: 2000029032
Do you have a 9- to 12-month-old infant?
We are looking for tobacco-smoking and non-smoking mothers with a 9- to 12-month-old infant. Volunteers will be mothers who complete two, 2-hour long visits at the Yale Child Study Center. During the first visit, volunteers will complete some questionnaires, then some play time and a free developmental assessment with their infant. During the second visit, volunteers (not their infants) will complete a simple computer task while we safely measure brain activity as well as completing some more questionnaires and cognitive tasks. There will also be some questionnaires to complete between visits.
Volunteers will be compensated $50 after each visit, for a total of $100. Travel compensation is available too.
To learn more please contact The Before and After Baby Lab (BABL) at (203) 901-1029 or Email: thebabl@yale.edu.
Sponsored by National Institute on Drug Abuse (NIDA); HIC# 200003108