Research Interests

Karen Anderson
Pharmacology
Structural and functional studies on proteins that are molecular targets for antiviral, antimicrobial, antiparasitic therapies.

• Anderson Lab

Richard Baxter
Chemistry
Structure-function studies of innate immune in Anopheles gambiae.

• Baxter Lab

Titus Boggon
Pharmacology
Structural studies into the mechanisms of regulation and dysregulation in signal transduction pathways.

• Boggon Lab

Demetrios Braddock
Pathology
Structures of protein complexes involved in the initiation, maintenance, and spread of cancer.

• Braddock Lab

Ya Ha
Pharmacology
Structure of membrane proteins, and relationship to human diseases.

Elias Lolis
Pharmacology
Structures and mechanisms of proteins involved in inflammation and cancer.

• Lolis Lab

J. Patrick Loria
Chemistry
How the dynamic and structural properties of proteins correlate with their function with particular emphasis on enzymes and allosterism.

• Loria Lab

Andrew Miranker
Molecular Biophysics and Biochemistry
Protein interactions, stability & folding

• Miranker Lab

Thomas Pollard
Molecular Biophysics and Biochemistry
Biochemical and biophysical studies of fission yeast on the molecular basis of cellular motility and cytokinesis

• Pollard Lab

Anna Marie Pyle
MCD Biology and Chemistry
Structure and function of catalytic RNA; RNA helicase mechanisms; Computational analysis of RNA structure

• Pyle Lab

Lynne Regan
Molecular Biophysics and Biochemistry
Protein Design. Protein-protein and protein-RNA interactions.

• Regan Lab

Karin Reinisch
Cell Biology
Macromolecular crystallography to study the molecular mechanisms underlying membrane trafficking.

• Reinisch Lab

Joseph Schlessinger
Pharmacology
Structural analysis of receptor tyrosine kinases and signaling proteins involved in normal processes and in cancer.

• Schlessinger Lab

Fred Sigworth
Cellular and Molecular Physiology
Studies of ion-channel proteins using novel cryo-EM methods.

• Sigworth Lab

Charles Sindelar
Molecular Biophysics and Biochemistry
Atomic-level mechanisms of cytoskeletal motor proteins and other molecular machines, using high-resolution cryo-electron microscopy and as well as other structure-based tools.

• Sindelar Lab

Satinder K. Singh
Cellular and Molecular Physiology
Structure, function, regulation, and pharmacology of signaling proteins implicated in neurological and neuropsychiatric diseases

Thomas Steitz
Molecular Biophysics and Biochemistry
Structural bases of the central dogma (DNA replication, transcription, translation)

• Steitz Lab

Scott Strobel
Molecular Biophysics and Biochemistry
1) hydrocarbon production by novel fungi as alternative fuel source and 2) RNA biochemistry.

• Strobel Lab

Yong Xiong
Molecular Biophysics and Biochemistry
Biochemical and structural studies on innate immune systems; HIV; fatty acid synthase (FAS); polyketide synthase (PKS); Viral vectors

• Xiong Lab