2022
Catheter ablation improves cardiovascular outcomes in patients with atrial fibrillation and heart failure: a meta-analysis of randomized controlled trials
Simader FA, Howard JP, Ahmad Y, Saleh K, Naraen A, Samways JW, Mohal J, Reddy RK, Kaza N, Keene D, Shun-Shin MJ, Francis DP, Whinnett ZI, Arnold AD. Catheter ablation improves cardiovascular outcomes in patients with atrial fibrillation and heart failure: a meta-analysis of randomized controlled trials. EP Europace 2022, 25: 341-350. PMID: 36305545, PMCID: PMC9934993, DOI: 10.1093/europace/euac173.Peer-Reviewed Original ResearchConceptsHeart failure hospitalizationCatheter ablationHeart failureMedical therapyFailure hospitalizationAtrial fibrillationCardiovascular outcomesPrimary analysisPre-specified primary endpointAtrial fibrillation catheter ablationCause mortalityPrimary endpointSecondary endpointsLower riskPatientsTherapyHospitalizationFibrillationTrialsMortalityLow heterogeneityAblationEndpointOutcomesFailure
2021
Sodium-glucose cotransporter 2 inhibitors in patients with heart failure: a systematic review and meta-analysis of randomized trials
Ahmad Y, Madhavan MV, Stone GW, Francis DP, Makkar R, Bhatt DL, Howard JP. Sodium-glucose cotransporter 2 inhibitors in patients with heart failure: a systematic review and meta-analysis of randomized trials. European Heart Journal - Quality Of Care And Clinical Outcomes 2021, 8: 383-390. PMID: 34617565, PMCID: PMC9170566, DOI: 10.1093/ehjqcco/qcab072.Peer-Reviewed Original ResearchConceptsHeart failure hospitalizationSGLT-2 inhibitorsSodium-glucose cotransporter 2 inhibitorsCotransporter 2 inhibitorsFailure hospitalizationCardiovascular mortalityHeart failureCause mortalityHazard ratioPre-specified primary endpointEjection fraction rangeIndividual clinical endpointsPrimary endpointSecondary endpointsComposite outcomeStandard careRandomized trialsClinical endpointsHospitalizationPatientsSystematic reviewMortalityTrialsEndpointInhibitors