2024
Factors associated with reporting left ventricular ejection fraction with 3D echocardiography in real‐world practice
Faridi K, Zhu Z, Shah N, Crandall I, McNamara R, Flueckiger P, Bachand K, Lombo B, Hur D, Agarwal V, Reinhardt S, Velazquez E, Sugeng L. Factors associated with reporting left ventricular ejection fraction with 3D echocardiography in real‐world practice. Echocardiography 2024, 41: e15774. PMID: 38329886, DOI: 10.1111/echo.15774.Peer-Reviewed Original ResearchConceptsTransthoracic echocardiogramVentricular ejection fractionOutpatient transthoracic echocardiogramsReal-world practiceEjection fractionLeft ventricular ejection fractionAssess left ventricular ejection fractionInpatient transthoracic echocardiogramsMultivariate logistic regressionLVEFHospitalized patientsMedical CenterSonographersClinical settingLogistic regressionUltrasound machineChemotherapyContrast enhancement agentsPortable studiesNegative association
2023
Severe aortic stenosis detection by deep learning applied to echocardiography
Holste G, Oikonomou E, Mortazavi B, Coppi A, Faridi K, Miller E, Forrest J, McNamara R, Ohno-Machado L, Yuan N, Gupta A, Ouyang D, Krumholz H, Wang Z, Khera R. Severe aortic stenosis detection by deep learning applied to echocardiography. European Heart Journal 2023, 44: 4592-4604. PMID: 37611002, PMCID: PMC11004929, DOI: 10.1093/eurheartj/ehad456.Peer-Reviewed Original ResearchConceptsSevere aortic stenosis
2022
Abnormal left atrial body stiffness is predicted by appendage size: impact of appendage occlusion on left atrial mechanics assessed by pressure-volume analysis
Bregasi A, Freeman JV, Curtis JP, Akar JG, Ortiz-Leon XA, Maia JH, Higgins AY, Matthews RV, Sinusas AJ, McNamara RL, Sugeng L, Lin BA. Abnormal left atrial body stiffness is predicted by appendage size: impact of appendage occlusion on left atrial mechanics assessed by pressure-volume analysis. AJP Heart And Circulatory Physiology 2022, 323: h559-h568. PMID: 35960632, PMCID: PMC9576173, DOI: 10.1152/ajpheart.00083.2022.Peer-Reviewed Original ResearchConceptsLeft atrial appendage occlusionLA stiffnessAppendage occlusionLA appendageLA mechanicsTransesophageal echocardiographyPressure-volume analysisPercutaneous left atrial appendage occlusionAdverse atrial remodelingAtrial appendage occlusionLeft atrial appendageLA volume measurementsAtrial cardiomyopathyBaseline characteristicsLA complianceAtrial remodelingClinical outcomesAtrial appendageAtrial mechanicsCardiac performancePathophysiological roleBaseline parametersMagnitude of increaseAppendage sizeOcclusion
2020
2020 Update to the 2016 ACC/AHA Clinical Performance and Quality Measures for Adults With Atrial Fibrillation or Atrial Flutter: A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures
Members W, Heidenreich P, Estes N, Fonarow G, Jurgens C, Kittleson M, Marine J, McManus D, McNamara R. 2020 Update to the 2016 ACC/AHA Clinical Performance and Quality Measures for Adults With Atrial Fibrillation or Atrial Flutter: A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures. Circulation Cardiovascular Quality And Outcomes 2020, 14: e000100. PMID: 33284642, DOI: 10.1161/hcq.0000000000000100.Peer-Reviewed Original Research
2019
Patient, clinician and logistic barriers to blood pressure control among adult hypertensives in rural district hospitals in Rwanda: a cross-sectional study
Sibomana J, McNamara R, Walker T. Patient, clinician and logistic barriers to blood pressure control among adult hypertensives in rural district hospitals in Rwanda: a cross-sectional study. BMC Cardiovascular Disorders 2019, 19: 231. PMID: 31638907, PMCID: PMC6805529, DOI: 10.1186/s12872-019-1203-3.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAntihypertensive AgentsBlood PressureClinical CompetenceCross-Sectional StudiesFemaleGuideline AdherenceHospitals, RuralHumansHypertensionMaleMedication AdherenceMiddle AgedPhysician's RolePractice Guidelines as TopicPractice Patterns, Physicians'RwandaTime FactorsTreatment OutcomeYoung AdultConceptsRural district hospitalDistrict hospitalsBlood pressure controlBarriers to effective blood pressure controlRural Rwandan district hospitalsAssociated with poor blood pressure controlRwandan district hospitalsBarriers to blood pressure controlPoor blood pressure controlMethodsThis cross-sectionalCross-sectional studyLogistical factorsMedication side effectsPressure controlAnti-hypertensive medicationsHypertensive patientsSociodemographic factorsBlood pressureBlood pressure dataPrescribed medicationsEffective blood pressure controlJNC 8 recommendationsGoal blood pressurePatient factorsMedical costs
2017
Contemporary risk model for inhospital major bleeding for patients with acute myocardial infarction: The acute coronary treatment and intervention outcomes network (ACTION) registry®–Get With The Guidelines (GWTG)®
Desai NR, Kennedy KF, Cohen DJ, Connolly T, Diercks DB, Moscucci M, Ramee S, Spertus J, Wang TY, McNamara RL. Contemporary risk model for inhospital major bleeding for patients with acute myocardial infarction: The acute coronary treatment and intervention outcomes network (ACTION) registry®–Get With The Guidelines (GWTG)®. American Heart Journal 2017, 194: 16-24. PMID: 29223432, DOI: 10.1016/j.ahj.2017.08.004.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionIntervention Outcomes Network RegistryAcute Coronary TreatmentInhospital major bleedingMajor bleedingRisk scoreCoronary TreatmentValidation cohortMyocardial infarctionHigh riskLower riskContemporary risk modelsProspective risk stratificationSimplified risk scoreHospital quality assessmentRisk adjustment methodsBaseline hemoglobinCardiogenic shockCreatinine clearanceFrequent complicationDerivation cohortHeart failureRisk stratificationSignificant morbidityCardiac arrest
2016
2016 ACC/AHA Clinical Performance and Quality Measures for Adults With Atrial Fibrillation or Atrial Flutter A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures
Heidenreich PA, Solis P, Estes NA, Fonarow GC, Jurgens CY, Marine JE, McManus DD, McNamara RL. 2016 ACC/AHA Clinical Performance and Quality Measures for Adults With Atrial Fibrillation or Atrial Flutter A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures. Journal Of The American College Of Cardiology 2016, 68: 525-568. PMID: 27364541, DOI: 10.1016/j.jacc.2016.03.521.Peer-Reviewed Original Research
2015
Development of a Hospital Outcome Measure Intended for Use With Electronic Health Records
McNamara RL, Wang Y, Partovian C, Montague J, Mody P, Eddy E, Krumholz HM, Bernheim SM. Development of a Hospital Outcome Measure Intended for Use With Electronic Health Records. Medical Care 2015, 53: 818-826. PMID: 26225445, DOI: 10.1097/mlr.0000000000000402.Peer-Reviewed Original ResearchConceptsElectronic health recordsOutcome measuresClinical dataMortality rateClinical practiceFuture quality improvement measuresRisk-standardized mortality ratesHospital risk-standardized mortality ratesLow-mortality hospitalsHealth recordsSystolic blood pressureOdds of mortalityClinical registry dataAcute myocardial infarctionHigh-mortality hospitalsHospital outcome measuresEHR dataFinal risk modelCurrent clinical practiceStandard clinical practiceFirst outcome measureNational Quality ForumCurrent electronic health recordsQuality improvement measuresChart abstractionStandardized Outcome Measurement for Patients With Coronary Artery Disease: Consensus From the International Consortium for Health Outcomes Measurement (ICHOM)
McNamara RL, Spatz ES, Kelley TA, Stowell CJ, Beltrame J, Heidenreich P, Tresserras R, Jernberg T, Chua T, Morgan L, Panigrahi B, Rosas Ruiz A, Rumsfeld JS, Sadwin L, Schoeberl M, Shahian D, Weston C, Yeh R, Lewin J. Standardized Outcome Measurement for Patients With Coronary Artery Disease: Consensus From the International Consortium for Health Outcomes Measurement (ICHOM). Journal Of The American Heart Association 2015, 4: e001767. PMID: 25991011, PMCID: PMC4599409, DOI: 10.1161/jaha.115.001767.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionHealth Outcomes MeasurementOutcome measurementsMyocardial infarctionCoronary artery disease outcomesPatient-reported health statusCoronary artery bypassPercutaneous coronary interventionCoronary artery diseasePatient-centered outcomesStandardized outcome measurementsLongitudinal outcomesCardiovascular hospital admissionsAsymptomatic CADAcute complicationsArtery bypassCoronary interventionRenal failureArtery diseaseHospital admissionInternational Working GroupRisk factorsCardiovascular diseaseDisease outcomeOutcome measures
2014
International comparisons of the management of patients with non-ST segment elevation acute myocardial infarction in the United Kingdom, Sweden, and the United States: The MINAP/NICOR, SWEDEHEART/RIKS-HIA, and ACTION Registry-GWTG/NCDR registries
McNamara RL, Chung SC, Jernberg T, Holmes D, Roe M, Timmis A, James S, Deanfield J, Fonarow GC, Peterson ED, Jeppsson A, Hemingway H. International comparisons of the management of patients with non-ST segment elevation acute myocardial infarction in the United Kingdom, Sweden, and the United States: The MINAP/NICOR, SWEDEHEART/RIKS-HIA, and ACTION Registry-GWTG/NCDR registries. International Journal Of Cardiology 2014, 175: 240-247. PMID: 24882696, PMCID: PMC4112832, DOI: 10.1016/j.ijcard.2014.04.270.Peer-Reviewed Original ResearchConceptsNon-ST segment elevation myocardial infarctionPercutaneous coronary interventionManagement of patientsMyocardial infarctionRIKS-HIAAcute non-ST segment elevation myocardial infarctionNon-ST segment elevation acute myocardial infarctionEnzyme inhibitors/angiotensin receptor blockersSegment elevation acute myocardial infarctionElevation acute myocardial infarctionSegment elevation myocardial infarctionFuture comparative effectiveness researchAngiotensin receptor blockersPrior heart failureDual antiplatelet agentsElevation myocardial infarctionAcute myocardial infarctionComparative effectiveness researchCoronary interventionDischarge medicationsOngoing registryReceptor blockersHeart failureAntiplatelet agentsClinical registry
2010
Cardiovascular registry research comes of age
McNamara RL. Cardiovascular registry research comes of age. Heart 2010, 96: 908. PMID: 20538664, DOI: 10.1136/hrt.2010.198069.Peer-Reviewed Original Research
2008
Systolic Function as a Predictor of Mortality and Quality of Life in Long‐term Survivors with Heart Failure
McNamara R, Austin B, Wang Y, Smith G, Vaccarine V, Krumholz H. Systolic Function as a Predictor of Mortality and Quality of Life in Long‐term Survivors with Heart Failure. Clinical Cardiology 2008, 31: 119-124. PMID: 18383045, PMCID: PMC6653267, DOI: 10.1002/clc.20118.Peer-Reviewed Original ResearchConceptsQuality of lifeEjection fractionHeart failureLong-term survivorsFunctional declineSystolic functionKansas City Cardiomyopathy Questionnaire scoreModest survival advantageReduced ejection fractionDaily living scoreDisease-related qualityPredictors of mortalityHeart failure patientsClinical summary scoreLong-term survivalHigh mortality rateKCCQ scoresRenal insufficiencyFailure patientsLiving scoreDiabetes mellitusOverall mortalityPrimary outcomeLimitation scoresQOL scoresACC/AHA/Physician Consortium 2008 Clinical Performance Measures for Adults With Nonvalvular Atrial Fibrillation or Atrial Flutter A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures and the Physician Consortium for Performance Improvement (Writing Committee to Develop Clinical Performance Measures for Atrial Fibrillation) Developed in Collaboration With the Heart Rhythm Society
Estes NA, Halperin JL, Calkins H, Ezekowitz MD, Gitman P, Go AS, McNamara RL, Messer JV, Ritchie JL, Romeo SJ, Waldo AL, Wyse DG, Bonow RO, DeLong E, Goff DC, Grady K, Green LA, Hiniker A, Linderbaum JA, Masoudi FA, Piña IL, Pressler S, Radford MJ, Rumsfeld JS. ACC/AHA/Physician Consortium 2008 Clinical Performance Measures for Adults With Nonvalvular Atrial Fibrillation or Atrial Flutter A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures and the Physician Consortium for Performance Improvement (Writing Committee to Develop Clinical Performance Measures for Atrial Fibrillation) Developed in Collaboration With the Heart Rhythm Society. Journal Of The American College Of Cardiology 2008, 51: 865-884. PMID: 18294574, DOI: 10.1016/j.jacc.2008.01.006.Peer-Reviewed Original Research
2007
Impact of Delay in Door-to-Needle Time on Mortality in Patients With ST-Segment Elevation Myocardial Infarction
McNamara RL, Herrin J, Wang Y, Curtis JP, Bradley EH, Magid DJ, Rathore SS, Nallamothu BK, Peterson ED, Blaney ME, Frederick P, Krumholz HM. Impact of Delay in Door-to-Needle Time on Mortality in Patients With ST-Segment Elevation Myocardial Infarction. The American Journal Of Cardiology 2007, 100: 1227-1232. PMID: 17920362, PMCID: PMC2715362, DOI: 10.1016/j.amjcard.2007.05.043.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overArrhythmias, CardiacCaliforniaCohort StudiesEmergency Service, HospitalEmergency TreatmentFemaleFibrinolytic AgentsHospital MortalityHumansMaleMedical RecordsMyocardial InfarctionOutcome Assessment, Health CareRegistriesRetrospective StudiesThrombolytic TherapyTime and Motion StudiesTime FactorsConceptsST-segment elevation myocardial infarctionElevation myocardial infarctionNeedle timeFibrinolytic therapyMyocardial infarctionHospital mortalitySymptom onsetOdds ratioReperfusion strategyAdjunctive medicationsHospital arrivalShorter doorTimely administrationNational registryRepresentative cohortPatientsMortalityInfarctionTherapyIndependent effectsCohortMinutesSmaller centersOnsetImpact of delay
2006
Strategies for Reducing the Door-to-Balloon Time in Acute Myocardial Infarction
Bradley EH, Herrin J, Wang Y, Barton BA, Webster TR, Mattera JA, Roumanis SA, Curtis JP, Nallamothu BK, Magid DJ, McNamara RL, Parkosewich J, Loeb JM, Krumholz HM. Strategies for Reducing the Door-to-Balloon Time in Acute Myocardial Infarction. New England Journal Of Medicine 2006, 355: 2308-2320. PMID: 17101617, DOI: 10.1056/nejmsa063117.Peer-Reviewed Original ResearchConceptsST-segment elevationBalloon timeCatheterization laboratoryMyocardial infarctionFaster doorEmergency departmentPrimary percutaneous coronary interventionHospital strategiesIntracoronary balloon inflationPercutaneous coronary interventionAcute myocardial infarctionMinority of hospitalsEmergency medicine physiciansReperfusion treatmentCoronary interventionBalloon inflationMedicine physiciansMultivariate analysisHospitalInfarctionPatientsMedicaid ServicesSignificant reductionReal-time data feedbackData feedbackAchieving Quality in Cardiovascular Imaging Proceedings From the American College of Cardiology–Duke University Medical Center Think Tank on Quality in Cardiovascular Imaging
Douglas P, Iskandrian AE, Krumholz HM, Gillam L, Hendel R, Jollis J, Peterson E, Douglas P, Chen J, Gillam L, Hendel R, Jollis J, Iskandrian A, Krumholz H, Masoudi F, Mohler E, McNamara R, Patel M, Peterson E, Spertus J. Achieving Quality in Cardiovascular Imaging Proceedings From the American College of Cardiology–Duke University Medical Center Think Tank on Quality in Cardiovascular Imaging. Journal Of The American College Of Cardiology 2006, 48: 2141-2151. PMID: 17113004, DOI: 10.1016/j.jacc.2006.06.076.Peer-Reviewed Original ResearchAnticoagulants or antiplatelet therapy for non‐rheumatic atrial fibrillation and flutter
Segal J, McNamara R, Miller M, Powe N, Goodman S, Robinson K, Bass E. Anticoagulants or antiplatelet therapy for non‐rheumatic atrial fibrillation and flutter. Cochrane Database Of Systematic Reviews 2006, 2010: cd001938. PMID: 17636690, PMCID: PMC10759270, DOI: 10.1002/14651858.cd001938.pub2.Peer-Reviewed Original ResearchConceptsAggregate odds ratioRisk of hemorrhageAtrial fibrillationStroke preventionMajor hemorrhageOdds ratioDose warfarinMajor bleedsModerate evidenceCochrane Collaboration's CENTRAL databaseNon-postoperative atrial fibrillationNon-rheumatic atrial fibrillationLow molecular weight heparinAdditional major bleedsLow-dose warfarinMore major bleedingMore major bleedsMore major hemorrhageRCTs of patientsPrimary stroke preventionLow-risk patientsRheumatic valvular diseasePrevention of thromboembolismRisk of strokeTrials of drugs
2005
Hospital Improvement in Time to Reperfusion in Patients With Acute Myocardial Infarction, 1999 to 2002
McNamara RL, Herrin J, Bradley EH, Portnay EL, Curtis JP, Wang Y, Magid DJ, Blaney M, Krumholz HM, Investigators N. Hospital Improvement in Time to Reperfusion in Patients With Acute Myocardial Infarction, 1999 to 2002. Journal Of The American College Of Cardiology 2005, 47: 45-51. PMID: 16386663, PMCID: PMC1475926, DOI: 10.1016/j.jacc.2005.04.071.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionBalloon timeMin/yearNeedle timeMyocardial infarctionHospital characteristicsAcute ST-segment elevation myocardial infarctionPercutaneous coronary intervention cohortPercutaneous coronary intervention volumeElevation myocardial infarctionPercutaneous coronary interventionRetrospective observational studyFour-year study periodRapid reperfusionCoronary interventionFibrinolytic therapyHospital arrivalTherapy cohortReperfusion timeIntervention cohortNational registryIntervention volumeObservational studyHospital improvementPatients
2003
Predictors of cause‐specific hospital readmission in patients with heart failure
Babayan Z, McNamara R, Nagajothi N, Kasper E, Armenian H, Powe N, Baughman K, Lima J. Predictors of cause‐specific hospital readmission in patients with heart failure. Clinical Cardiology 2003, 26: 411-418. PMID: 14524597, PMCID: PMC6654034, DOI: 10.1002/clc.4960260906.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryCohort StudiesCoronary Artery BypassFemaleFollow-Up StudiesHeart FailureHumansLength of StayMaleMarylandMiddle AgedMyocardial IschemiaPatient ReadmissionPredictive Value of TestsPrevalenceRecurrenceRegression AnalysisSex FactorsStroke VolumeTime FactorsVentricular Dysfunction, LeftConceptsCause-specific readmissionsCoronary artery bypass graftPercutaneous transluminal coronary angioplastyIschemic etiologyRecurrent heart failureHeart failureCardiovascular diseaseHospital readmissionLV dysfunctionVentricular functionMyocardial infarctionAnnual readmission ratesTotal hospital readmissionsArtery bypass graftRisk of readmissionTransluminal coronary angioplastyLeft ventricular functionCox hazard ratiosAvailable clinical dataCause readmissionHF etiologyHazard ratioReadmission ratesRetrospective cohortConsecutive patients
2001
Evidence-based Practice Centers: Production of Evidence Report on Management of Atrial Fibrillation
Robinson K, McNamara R, Bass E, Powe N. Evidence-based Practice Centers: Production of Evidence Report on Management of Atrial Fibrillation. AACN Advanced Critical Care 2001, 12: 618-627. PMID: 11759433, DOI: 10.1097/00044067-200111000-00018.Peer-Reviewed Original ResearchConceptsEvidence-based Practice CenterEvidence reportPractice centerAtrial fibrillationJohns Hopkins EvidenceEvidence-based careEvidence-based healthcareSpecific clinicSynthesis of evidenceSpecific patientHealthcare ResearchHealthcare practitionersIndividual basisFibrillationEvidence-based productsReportData abstractionPatients