Pengfei Guo, MBBS, PhD
Postdoctoral AssociateAbout
Research
Publications
2024
Association between Personal Abiotic Airborne Exposures and Body Composition Changes among Healthy Adults (60–69 Years Old): A Combined Exposome-Wide and Lipidome Mediation Approach from the China BAPE Study
Sun P, Guo X, Ding E, Li C, Ren H, Xu Y, Qian J, Deng F, Shi W, Dong H, Lin E, Guo P, Fang J, Zhang Q, Zhao W, Tong S, Lu X, Pollitt K, Shi X, Tang S. Association between Personal Abiotic Airborne Exposures and Body Composition Changes among Healthy Adults (60–69 Years Old): A Combined Exposome-Wide and Lipidome Mediation Approach from the China BAPE Study. Environmental Health Perspectives 2024, 132: 077005. PMID: 39028628, PMCID: PMC11259245, DOI: 10.1289/ehp13865.Peer-Reviewed Original ResearchConceptsFat mass indicatorsHealthy older adultsBayesian kernel machine regressionVisceral fat areaOlder adultsPercent body fatBody compositionBody fat massExposome-wide association studyPrevention of chronic diseasesAir pollution exposureBody composition indicatorsMediation analysisInBody 770 deviceHealthy adultsAssociated with increased body fat massBody composition changesKernel machine regressionBayesian kernel machine regression modelsChronic diseasesPollution exposureBody fatAssociation studiesAdverse health effectsFat areaPersonal exposure to airborne organic pollutants and lung function changes among healthy older adults
Guo X, Ren H, Sun P, Ding E, Fang J, Fang K, Ma X, Li C, Li C, Xu Y, Cao K, Lin E, Guo P, Pollitt K, Tong S, Tang S, Shi X. Personal exposure to airborne organic pollutants and lung function changes among healthy older adults. Environmental Research 2024, 258: 119411. PMID: 38876423, DOI: 10.1016/j.envres.2024.119411.Peer-Reviewed Original Research
2023
Per- and polyfluoroalkyl substances and sleep health in U.S. adults, NHANES 2005–2014
Guo P, Jin Z, Bellia G, Luo J, Inoue K, Pollitt K, Deziel N, Liew Z. Per- and polyfluoroalkyl substances and sleep health in U.S. adults, NHANES 2005–2014. Environmental Research 2023, 237: 117092. PMID: 37683785, DOI: 10.1016/j.envres.2023.117092.Peer-Reviewed Original ResearchSleep disordersSleep outcomesU.S. adultsNHANES 2005Inverse associationSleep durationSerum polyfluoroalkyl substancesCentral nervous systemSerum concentration dataDaily sleep durationExposure tertilesOxidative inflammatory responseQuartile increaseBias analysisInflammatory responseExcessive sleepUncontrolled confoundingNervous systemSleep healthPFAS exposureHealth measuresQuantitative bias analysisLogistic regressionConsistent associationDisorders
2022
Human health effects of chemical mixtures
Liew Z, Guo P. Human health effects of chemical mixtures. Science 2022, 375: 720-721. PMID: 35175805, PMCID: PMC9805352, DOI: 10.1126/science.abn9080.Commentaries, Editorials and Letters
2021
Adherence to Traditional Chinese Postpartum Practices and Postpartum Depression: A Cross-Sectional Study in Hunan, China
Guo P, Xu D, Liew Z, He H, Brocklehurst P, Taylor B, Zhang C, Jin X, Gong W. Adherence to Traditional Chinese Postpartum Practices and Postpartum Depression: A Cross-Sectional Study in Hunan, China. Frontiers In Psychiatry 2021, 12: 649972. PMID: 34385937, PMCID: PMC8353075, DOI: 10.3389/fpsyt.2021.649972.Peer-Reviewed Original ResearchExploring personal chemical exposures in China with wearable air pollutant monitors: A repeated-measure study in healthy older adults in Jinan, China
Guo P, Lin EZ, Koelmel JP, Ding E, Gao Y, Deng F, Dong H, Liu Y, Cha Y, Fang J, Shi X, Tang S, Godri Pollitt KJ. Exploring personal chemical exposures in China with wearable air pollutant monitors: A repeated-measure study in healthy older adults in Jinan, China. Environment International 2021, 156: 106709. PMID: 34153889, DOI: 10.1016/j.envint.2021.106709.Peer-Reviewed Original ResearchConceptsVolatile organic compoundsPolycyclic aromatic hydrocarbonsAirborne chemical contaminantsPersonal exposure profilesPassive air samplersOrganic compoundsPassive samplersChemical classesChemical contaminantsChemical analysisPersonal chemical exposureCertain polycyclic aromatic hydrocarbonsChemical exposureAirborne compoundsAirborne contaminantsCompoundsAromatic hydrocarbonsContaminantsAir monitoring sitesComprehensive characterizationPhthalateNitroaromaticsRepeated-measures studyAir samplerNitrobenzeneHead, Shoulders, Knees, and Toes: Placement of Wearable Passive Samplers Alters Exposure Profiles Observed
Koelmel JP, Lin EZ, Nichols A, Guo P, Zhou Y, Pollitt K. Head, Shoulders, Knees, and Toes: Placement of Wearable Passive Samplers Alters Exposure Profiles Observed. Environmental Science And Technology 2021, 55: 3796-3806. PMID: 33625210, DOI: 10.1021/acs.est.0c05522.Peer-Reviewed Original ResearchConceptsSemivolatile organic compoundsOrganic compoundsGas chromatography-high resolution mass spectrometryPassive samplersHigh-resolution mass spectrometryVolatile organic compoundsPersonal exposure profilesChemicals of concernMass spectrometryChemicalsExposure dynamicsExposure profilesCompoundsMajor risk factorComprehensive characterizationPersonal exposureAirborne contaminantsContaminant exposureRisk factorsInhalation routeEpidemiological studiesChemical exposureSpectrometrySamplerParticipants' wrists