2021
Uncertainty in tissue equivalent proportional counter assessments of microdosimetry and RBE estimates in carbon radiotherapy
Hartzell S, Guan F, Taylor P, Peterson C, Taddei P, Kry S. Uncertainty in tissue equivalent proportional counter assessments of microdosimetry and RBE estimates in carbon radiotherapy. Physics In Medicine And Biology 2021, 66: 155018. PMID: 34252894, DOI: 10.1088/1361-6560/ac1366.Peer-Reviewed Original ResearchConceptsTissue equivalent proportional counterCommon mathematical modelPerturbed valuesMicrodosimetric kinetic modelLow-energy cutMonte Carlo toolkitMathematical modelCounting statisticsCentral beam axisEnergy deposition distributionsStatistic uncertaintyInput parametersTherapeutic carbon beamsLineal energy valuesCarbon beamBeam axisTEPC measurementsSources of uncertaintyWall effectsModel input parametersMicrodosimetric spectraInherent uncertaintyRelative biological effectivenessUncertaintyCarbon radiotherapy
2018
Power-law relationship in the long-tailed sections of proton dose distributions
Jiang B, Wang X, Zhang Y, Guan F, Li Y, Wang X, Zhu RX, Zhang X. Power-law relationship in the long-tailed sections of proton dose distributions. Scientific Reports 2018, 8: 10413. PMID: 29991734, PMCID: PMC6039508, DOI: 10.1038/s41598-018-28683-5.Peer-Reviewed Original ResearchConceptsIndirect impact mechanismMathematical modelDose distributionPower-law exponentLateral dose distributionProton dose distributionsStatistical methodsImpact probabilityPower law relationshipDirect impact mechanismHalo portionDose profilesDose depositionExperimental dataLong tailProbabilityDistributionProton impactExponent