2022
Ki‐67 index assessment on FNA specimens of gastrointestinal stromal tumor: Correlation with mitotic rate and potential predictive value for risk stratification
Wang X, Abi‐Raad R, Tang H, Cai G. Ki‐67 index assessment on FNA specimens of gastrointestinal stromal tumor: Correlation with mitotic rate and potential predictive value for risk stratification. Cancer Cytopathology 2022, 130: 974-982. PMID: 35876606, DOI: 10.1002/cncy.22630.Peer-Reviewed Original ResearchConceptsGastrointestinal stromal tumorsKi-67 indexHigh mitotic rateLow mitotic rateCell block sectionsMitotic rateMitotic countRisk stratificationStromal tumorsSurgical specimensRisk of GISTCytology specimensMean Ki-67 indexPotential predictive valueBlock sectionsFine-needle aspiration specimensKi-67 immunostainLMR groupSurgical resectionDistal esophagusTumor sizeSpindle cellsGIST casesFNA specimensPredictive valueCOVID-19 & differential effects in twins: Insights from Placenta Pathology
Moriarty K, Yu M, Hussain N, Zgutka K, Sanders MM, Harigopal M, Wang J, Wang X, Hui P, Liu C, Sink D, Shields A. COVID-19 & differential effects in twins: Insights from Placenta Pathology. Placenta 2022, 124: 62-66. PMID: 35640456, PMCID: PMC9121647, DOI: 10.1016/j.placenta.2022.05.014.Peer-Reviewed Original ResearchConceptsSARS-CoV-2Perinatal lossCOVID-19Adverse pregnancy outcomesMaternal-fetal interfaceTime of infectionDifferential effectsPregnancy outcomesPremature deliveryFetal interfaceGestational agePlacenta pathologyTwin pregnanciesMembranous expressionFemale fetusesFetal sexViral detection methodsViral receptorsFemale twinsTissue resultsPregnancyPlacentaTask ForceSuccumbedFetusesHepatocellular adenoma: Where are we now?
Wang X, Zhang X. Hepatocellular adenoma: Where are we now? World Journal Of Gastroenterology 2022, 28: 1384-1393. PMID: 35582672, PMCID: PMC9048476, DOI: 10.3748/wjg.v28.i14.1384.Peer-Reviewed Original ResearchConceptsHepatocellular adenomaOral contraceptive useUnderlying molecular signaturesClinical managementHepatocellular neoplasmsContraceptive useHigh riskMalignant transformationYoung womenMolecular featuresMolecular signaturesSubtypesMolecular studiesClassification systemComplicationsHemorrhageAdenomasNeoplasmsNeuropathology of Chiari Malformation II with Chromosome X Alterations: An Autopsy Study in a 17-Month-Old and Review of Literature
Wang X, Habet V, Aboian M, Leelatian N, McGuone D, Morotti R, Kandil S, Darbinyan A. Neuropathology of Chiari Malformation II with Chromosome X Alterations: An Autopsy Study in a 17-Month-Old and Review of Literature. Journal Of Neuropathology & Experimental Neurology 2022, 81: 296-298. PMID: 35139536, DOI: 10.1093/jnen/nlab137.Peer-Reviewed Original Research
2021
Somatic Mutation of BAP1 Can Lead to Expression Loss in Non-Small Cell Lung Carcinoma: Next Generation Sequencing and IHC Analysis in A Large Single Institute Cohort
Sun T, Wang X, Wang M, Minerowicz C, Sanchez H, Laskin W, Cohen P, Zhong M. Somatic Mutation of BAP1 Can Lead to Expression Loss in Non-Small Cell Lung Carcinoma: Next Generation Sequencing and IHC Analysis in A Large Single Institute Cohort. International Journal Of Surgical Pathology 2021, 30: 512-519. PMID: 34970936, DOI: 10.1177/10668969211070179.Peer-Reviewed Original ResearchConceptsNon-small cell lung carcinomaCell lung carcinomaLung carcinomaCell carcinomaSomatic mutationsClear cell renal cell carcinomaExpression lossCell renal cell carcinomaSquamous cell carcinomaNext-generation sequencingGenetic alterationsRenal cell carcinomaBAP1 protein expressionProtein expression statusStudy cohortNSCLC casesNSCLC tumorsLoss of expressionNeural tumorsAdditional genetic alterationsCommon findingIHC analysisNSCLC carcinogenesisIRB approvalMelanocytic tumors