2005
Estrogen therapy and risk of cognitive decline: Results from the Women's Estrogen for Stroke Trial (WEST)
Viscoli CM, Brass LM, Kernan WN, Sarrel PM, Suissa S, Horwitz RI. Estrogen therapy and risk of cognitive decline: Results from the Women's Estrogen for Stroke Trial (WEST). American Journal Of Obstetrics And Gynecology 2005, 192: 387-393. PMID: 15695976, DOI: 10.1016/j.ajog.2004.08.017.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCognitionDouble-Blind MethodEstradiolFemaleHumansMiddle AgedPostmenopauseStrokeConceptsMini-Mental State ExaminationEstrogen therapyCognitive declineNormal Mini-Mental State ExaminationDouble-blind trialSecondary stroke preventionTransient ischemic attackIschemic attackPostmenopausal womenStroke preventionRecent strokeStroke trialsCerebrovascular diseaseWomen's EstrogenEstradiol-17betaState ExaminationCognitive measuresEstrogenWomenNormal functionDomain measuresLess declineTherapyStrokeRiskDecline in Physical Performance Among Women With a Recent Transient Ischemic Attack or Ischemic Stroke
Kernan WN, Viscoli CM, Brass LM, Gill TM, Sarrel PM, Horwitz RI. Decline in Physical Performance Among Women With a Recent Transient Ischemic Attack or Ischemic Stroke. Stroke 2005, 36: 630-634. PMID: 15677573, DOI: 10.1161/01.str.0000155728.42847.de.Peer-Reviewed Original ResearchConceptsTransient ischemic attackIschemic strokePhysical performance testsPhysical performanceIschemic attackRecent transient ischemic attackRecent ischemic strokeRecurrent neurological eventsAbsence of recurrenceLong-term disabilityEstrogen therapyRecurrent strokePostmenopausal womenNeurological eventsClinical trialsPPT scoresBaseline scoresFunctional independenceStrokeSpecific interventionsSubsequent strokeWomenSustained declineScoresBaseline
2002
Clinical assessment of function among women with a recent cerebrovascular event: a self-reported versus performance-based measure.
Owens PL, Bradley EH, Horwitz SM, Viscoli CM, Kernan WN, Brass LM, Sarrel PM, Horwitz RI. Clinical assessment of function among women with a recent cerebrovascular event: a self-reported versus performance-based measure. Annals Of Internal Medicine 2002, 136: 802-11. PMID: 12044128, DOI: 10.7326/0003-4819-136-11-200206040-00008.Peer-Reviewed Original ResearchConceptsLong-term health outcomesRecent cerebrovascular eventsLevel of functionCerebrovascular eventsPerformance-based measuresHealth outcomesSelf-reported functional statusTransient ischemic attackProspective cohort studyPhysical performance testsSelf-report measuresIschemic attackPostmenopausal womenBarthel IndexCohort studyNonwhite ethnicityFunctional statusClinical assessmentMost womenHealth measuresClinical settingSubsequent strokeWomenOutcomesStroke
2001
A Clinical Trial of Estrogen-Replacement Therapy after Ischemic Stroke
Viscoli C, Brass L, Kernan W, Sarrel P, Suissa S, Horwitz R. A Clinical Trial of Estrogen-Replacement Therapy after Ischemic Stroke. New England Journal Of Medicine 2001, 345: 1243-1249. PMID: 11680444, DOI: 10.1056/nejmoa010534.Peer-Reviewed Original ResearchConceptsEstrogen replacement therapyEstrogen therapyNonfatal strokePostmenopausal womenIschemic strokeCerebrovascular diseasePlacebo-controlled trialTransient ischemic attackOccurrence of strokeRisk of deathIschemic attackFatal strokeMean followPlacebo groupSecondary preventionEstradiol groupFunctional deficitsClinical trialsObservational studyHigh riskWoman's riskTherapyStrokeWomenDeath