2005
Association between Impaired Insulin Sensitivity and Stroke
Bravata DM, Wells CK, Kernan WN, Concato J, Brass LM, Gulanski BI. Association between Impaired Insulin Sensitivity and Stroke. Neuroepidemiology 2005, 25: 69-74. PMID: 15947493, DOI: 10.1159/000086286.Peer-Reviewed Original ResearchConceptsHomeostasis model assessmentInsulin sensitivityGlycemic controlMultivariable logistic regression analysisStroke risk factorsLower insulin sensitivityThird National HealthImpaired insulin sensitivityLogistic regression analysisStroke historyInsulin resistancePlasma insulinPlasma glucoseRisk factorsNational HealthNutrition SurveyModel assessmentStrokeRegression analysisAssociationParticipantsClaudicationInsulin
2004
Type 2 diabetes mellitus and insulin resistance: Stroke prevention and management
Kernan WN, Inzucchi SE. Type 2 diabetes mellitus and insulin resistance: Stroke prevention and management. Current Treatment Options In Neurology 2004, 6: 443-450. PMID: 15461922, DOI: 10.1007/s11940-004-0002-y.Peer-Reviewed Original ResearchType 2 diabetes mellitusDiabetes mellitusInsulin resistanceAntiplatelet therapyIschemic strokeMost patientsGlycemic controlLipid metabolismLowdensity lipoprotein cholesterolRecent ischemic strokeRecurrent ischemic strokeBlood pressure controlFirst-line therapyImpaired glucose toleranceSmooth muscle cell proliferationPrevention of diabetesTight glycemic controlBlood pressure regulationEffects of hyperglycemiaMajor underlying defectMuscle cell proliferationAspirin dailyClopidogrel dailyOccult diabetesMacrovascular disease