2009
Indications, Labeling, and Outcomes Assessment for Drugs Aimed at Improving Functional Status in Older Persons: A Conversation Between Aging Researchers and FDA Regulators
Bhasin S, Espeland M, Evans W, Ferrucci L, Fried L, Gill T, Pahor M, Studenski S, Guralnik J, Nayfield S, Romashkin S, Perlstein R, Burke L, Parks M. Indications, Labeling, and Outcomes Assessment for Drugs Aimed at Improving Functional Status in Older Persons: A Conversation Between Aging Researchers and FDA Regulators. The Journals Of Gerontology Series A 2009, 64A: 487-491. PMID: 19270182, PMCID: PMC2657175, DOI: 10.1093/gerona/gln042.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsActivities of Daily LivingAgedAged, 80 and overAgingCognition DisordersDose-Response Relationship, DrugFemaleFrail ElderlyGeriatric AssessmentHumansInterdisciplinary CommunicationMaleOutcome Assessment, Health CarePharmaceutical PreparationsPhysical FitnessPractice Guidelines as TopicResearchRisk AssessmentSensitivity and SpecificityUnited StatesUnited States Food and Drug Administration
2000
Role of Exercise Stress Testing and Safety Monitoring for Older Persons Starting an Exercise Program
Gill TM, DiPietro L, Krumholz HM. Role of Exercise Stress Testing and Safety Monitoring for Older Persons Starting an Exercise Program. JAMA 2000, 284: 342-349. PMID: 10891966, DOI: 10.1001/jama.284.3.342.Peer-Reviewed Original ResearchConceptsExercise stress testingAdverse cardiac eventsExercise programOlder personsCardiac eventsStress testingPhysical activityRoutine exercise stress testingSedentary older personsSymptomatic cardiovascular diseasePharmacological stress testingCurrent physician practiceRelative exercise intensityMajority of personsUnproven benefitPhysical functionCurrent guidelinesCardiovascular diseaseExercise intensityPhysician practicesSafety monitoringRiskExercisePersonsTesting
1997
The Role of Change in Physical Performance in Determining Risk for Dependence in Activities of Daily Living Among Nondisabled Community-Living Elderly Persons
Gill T, Williams C, de Leon C, Tinetti M. The Role of Change in Physical Performance in Determining Risk for Dependence in Activities of Daily Living Among Nondisabled Community-Living Elderly Persons. Journal Of Clinical Epidemiology 1997, 50: 765-772. PMID: 9253386, DOI: 10.1016/s0895-4356(97)00065-6.Peer-Reviewed Original ResearchConceptsUseful prognostic informationADL dependencePhysical performanceElderly personsPrognostic informationDaily livingCommunity-living elderly personsSingle assessmentLarge representative cohortAssessment of changesFuture disabilityBaseline interviewRepresentative cohortPowerful predictorRole of changesRiskParticipantsShort intervalsYearsAssessmentBaseline performancePersonsCohortYear interviewsADL