2017
Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance
Manson AL, Cohen KA, Abeel T, Desjardins CA, Armstrong DT, Barry CE, Brand J, Chapman S, Cho S, Gabrielian A, Gomez J, Jodals A, Joloba M, Jureen P, Lee J, Malinga L, Maiga M, Nordenberg D, Noroc E, Romancenco E, Salazar A, Ssengooba W, Velayati A, Winglee K, Zalutskaya A, Via L, Cassell G, Dorman S, Ellner J, Farnia P, Galagan J, Rosenthal A, Crudu V, Homorodean D, Hsueh P, Narayanan S, Pym A, Skrahina A, Swaminathan S, Van der Walt M, Alland D, Bishai W, Cohen T, Hoffner S, Birren B, Earl A. Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance. Nature Genetics 2017, 49: 395-402. PMID: 28092681, PMCID: PMC5402762, DOI: 10.1038/ng.3767.Peer-Reviewed Original Research
2004
Isoniazid Resistance and the Future of Drug-Resistant Tuberculosis
Cohen T, Becerra MC, Murray MB. Isoniazid Resistance and the Future of Drug-Resistant Tuberculosis. Microbial Drug Resistance 2004, 10: 280-285. PMID: 15650371, PMCID: PMC2652757, DOI: 10.1089/mdr.2004.10.280.Peer-Reviewed Original ResearchConceptsIsoniazid resistanceDrug resistanceDrug-resistant tuberculosisDrug-resistant casesResistance-conferring mutationsFrequency of resistanceMycobacterium tuberculosisAntibiotic resistancePrudent useTuberculosisDeleterious effectsReproductive potentialChromosomal mutationsMutationsSpecific measuresPrevalence