2022
A spatial-mechanistic model to estimate subnational tuberculosis burden with routinely collected data: An application in Brazilian municipalities
Chitwood M, Alves L, Bartholomay P, Couto R, Sanchez M, Castro M, Cohen T, Menzies N. A spatial-mechanistic model to estimate subnational tuberculosis burden with routinely collected data: An application in Brazilian municipalities. PLOS Global Public Health 2022, 2: e0000725. PMID: 36962578, PMCID: PMC10021638, DOI: 10.1371/journal.pgph.0000725.Peer-Reviewed Original ResearchPerson/yearTB incidenceCase notificationBurden estimatesIncident TB casesTB case notificationTB control strategiesDisease burden estimatesIncident TBUntreated TBTB casesTuberculosis burdenDisease burdenIncidence rateCase detectionRoutine dataDeath recordsMortality dataIncidenceSubnational estimatesDisease control resourcesBurdenHigh needTBFraction of individuals
2021
The impact of COVID-19 on TB: a review of the data
McQuaid C, Vassall A, Cohen T, Fiekert K, COVID/TB Modelling Working Group *, White R. The impact of COVID-19 on TB: a review of the data. The International Journal Of Tuberculosis And Lung Disease 2021, 25: 436-446. PMID: 34049605, PMCID: PMC8171247, DOI: 10.5588/ijtld.21.0148.Peer-Reviewed Original Research
2018
The impact of migration on tuberculosis in the United States
Menzies NA, Hill AN, Cohen T, Salomon JA. The impact of migration on tuberculosis in the United States. The International Journal Of Tuberculosis And Lung Disease 2018, 22: 1392-1403. PMID: 30606311, PMCID: PMC6353558, DOI: 10.5588/ijtld.17.0185.Peer-Reviewed Original ResearchConceptsTB casesTB burdenHigher tuberculosis ratesNew TB casesLow-incidence settingsEntry yearActive TBTB epidemiologyTB riskIncidence estimatesTuberculosis ratesLifetime casesUnited StatesRiskPopulation residentGreater exposureBurdenNative-born populationPopulationCountry of originTBYearsTuberculosisCasesInfection
2016
Assessing Local Risk of Rifampicin-Resistant Tuberculosis in KwaZulu-Natal, South Africa Using Lot Quality Assurance Sampling
Heidebrecht CL, Podewils LJ, Pym A, Mthiyane T, Cohen T. Assessing Local Risk of Rifampicin-Resistant Tuberculosis in KwaZulu-Natal, South Africa Using Lot Quality Assurance Sampling. PLOS ONE 2016, 11: e0153143. PMID: 27050561, PMCID: PMC4822784, DOI: 10.1371/journal.pone.0153143.Peer-Reviewed Original ResearchConceptsIncident TB casesTB casesResistant TBDrug-resistant TB casesRifampicin-resistant tuberculosisMultidrug-resistant tuberculosisDrug susceptibility testingRIF-resistant TBLot Quality Assurance SamplingQuality assurance samplingResistant diseaseHigh burdenRIF resistanceKwaZulu-NatalSusceptibility testingHigh-risk areasTuberculosisRiskGreater proportionBurdenTBDiseaseGeographic heterogeneityCasesRifampicin
2015
Evaluating the potential impact of enhancing HIV treatment and tuberculosis control programmes on the burden of tuberculosis
Chindelevitch L, Menzies NA, Pretorius C, Stover J, Salomon JA, Cohen T. Evaluating the potential impact of enhancing HIV treatment and tuberculosis control programmes on the burden of tuberculosis. Journal Of The Royal Society Interface 2015, 12: 20150146. PMID: 25878131, PMCID: PMC4424692, DOI: 10.1098/rsif.2015.0146.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyTB incidenceTB burdenBurden of tuberculosisTuberculosis Control ProgrammePotential epidemiological impactART eligibilityMortality benefitTB programsHIV treatmentTB prevalenceTuberculosis incidenceEpidemiological impactART useProgram improvementHIVTreatment effectivenessIncidenceMortalityGreater reductionBurdenTBSaharan AfricaControl programsEligibility
2011
Multiple Introductions of Multidrug-Resistant Tuberculosis into Households, Lima, Peru - Volume 17, Number 6—June 2011 - Emerging Infectious Diseases journal - CDC
Cohen T, Murray M, Abubakar I, Zhang Z, Sloutsky A, Arteaga F, Chalco K, Franke MF, Becerra MC. Multiple Introductions of Multidrug-Resistant Tuberculosis into Households, Lima, Peru - Volume 17, Number 6—June 2011 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2011, 17: 969-975. PMID: 21749756, PMCID: PMC3358204, DOI: 10.3201/eid1706.101471.Peer-Reviewed Original ResearchConceptsMDR-TB patientsMDR-TBMultidrug-resistant tuberculosisTB patientsOptimal treatment regimensMDR Mycobacterium tuberculosisDrug sensitivity testingHigh incidence areaRepetitive unit-variable number tandem repeatHousehold contactsTreatment regimensHousehold transmissionSecondary casesPatientsMycobacterium tuberculosisSensitivity testingCommunity exposureTuberculosisNumber tandem repeatTBSecond strainExposureRegimensSpoligotypingSpontaneous Emergence of Multiple Drug Resistance in Tuberculosis before and during Therapy
Colijn C, Cohen T, Ganesh A, Murray M. Spontaneous Emergence of Multiple Drug Resistance in Tuberculosis before and during Therapy. PLOS ONE 2011, 6: e18327. PMID: 21479171, PMCID: PMC3068161, DOI: 10.1371/journal.pone.0018327.Peer-Reviewed Original ResearchConceptsMultiple drug resistanceDrug resistanceInitial treatment regimensTB control programsAnti-TB drugsDrug-resistant formsEmergence of resistanceFunctional monotherapyTreatment regimensCombination therapyTB strainsTuberculosis treatmentTherapy rangeM. tbTB bacilliMultidrug resistanceM. tuberculosisDifferent antibioticsTherapyTuberculosisInfected hostControl programsResistant formsTBMonotherapy
2010
Assessing spatiotemporal patterns of multidrug-resistant and drug-sensitive tuberculosis in a South American setting
LIN H, SHIN S, BLAYA JA, ZHANG Z, CEGIELSKI P, CONTRERAS C, ASENCIOS L, BONILLA C, BAYONA J, PACIOREK CJ, COHEN T. Assessing spatiotemporal patterns of multidrug-resistant and drug-sensitive tuberculosis in a South American setting. Epidemiology And Infection 2010, 139: 1784-1793. PMID: 21205434, PMCID: PMC3153578, DOI: 10.1017/s0950268810002797.Peer-Reviewed Original ResearchConceptsTB casesMDR diseaseMultidrug-resistant tuberculosis (MDR-TB) casesDrug-sensitive tuberculosisDrug-resistant diseaseDrug susceptibility testingMDR-TBMDR casesTuberculosis casesIncident casesSubgroup analysisInfection controlK statisticInfectious durationAppearance of resistanceDistricts of LimaSusceptibility testingDiseasePatientsTBUrban settingsCasesTuberculosisSettingMDR
2009
Extensively Drug‐Resistant Tuberculosis and HIV/AIDS
Murray M, Cohen T. Extensively Drug‐Resistant Tuberculosis and HIV/AIDS. 2009, 253-275. DOI: 10.1002/9783527627905.ch10.Peer-Reviewed Original ResearchMathematical models of the epidemiology and control of drug-resistant TB
Cohen T, Dye C, Colijn C, Williams B, Murray M. Mathematical models of the epidemiology and control of drug-resistant TB. Expert Review Of Respiratory Medicine 2009, 3: 67-79. PMID: 20477283, DOI: 10.1586/17476348.3.1.67.Peer-Reviewed Original ResearchDrug-resistant TBDrug resistanceMultiple drug-resistant Mycobacterium tuberculosisDrug-resistant Mycobacterium tuberculosisDrug-resistant M. tuberculosisCombination chemotherapyTB controlM. tuberculosisMycobacterium tuberculosisAntibiotic resistanceRecent reportsTuberculosisEpidemiologyTBExtrinsic determinantsInterventionCost effectivenessReproductive capacityChemotherapyControlPrevalence
2006
Beneficial and perverse effects of isoniazid preventive therapy for latent tuberculosis infection in HIV–tuberculosis coinfected populations
Cohen T, Lipsitch M, Walensky RP, Murray M. Beneficial and perverse effects of isoniazid preventive therapy for latent tuberculosis infection in HIV–tuberculosis coinfected populations. Proceedings Of The National Academy Of Sciences Of The United States Of America 2006, 103: 7042-7047. PMID: 16632605, PMCID: PMC1459015, DOI: 10.1073/pnas.0600349103.Peer-Reviewed Original ResearchConceptsIsoniazid preventive therapyDrug-resistant TBCommunity-wide isoniazid preventive therapyPreventive therapyTuberculosis infectionTB controlLatent Mycobacterium tuberculosis infectionLatent tuberculosis infectionProportion of patientsMycobacterium tuberculosis infectionIncidence of TBTuberculosis case notificationCommunity-wide implementationEmergence of HIVCommunity-wide strategiesHIV-tuberculosisTB-HIVCoinfected individualsTB epidemicCase notificationTreatment policyHIVTherapyInfectionTB