High Rates of Potentially Infectious Tuberculosis and Multidrug-Resistant Tuberculosis (MDR-TB) among Hospital Inpatients in KwaZulu Natal, South Africa Indicate Risk of Nosocomial Transmission
Bantubani N, Kabera G, Connolly C, Rustomjee R, Reddy T, Cohen T, Pym AS. High Rates of Potentially Infectious Tuberculosis and Multidrug-Resistant Tuberculosis (MDR-TB) among Hospital Inpatients in KwaZulu Natal, South Africa Indicate Risk of Nosocomial Transmission. PLOS ONE 2014, 9: e90868. PMID: 24625669, PMCID: PMC3953209, DOI: 10.1371/journal.pone.0090868.Peer-Reviewed Original ResearchConceptsMultidrug-resistant tuberculosisCurrent coughXDR-TBNosocomial transmissionInfectious tuberculosisInfectious TBHospital inpatientsClinical dataAnti-tuberculosis drug susceptibility testingMDR/XDR-TBPrevious TB treatmentDrug susceptibility testingTB treatmentHospital admissionMale sexTB inpatientsScotland hospitalsInpatient settingHigh burdenSputum samplesInfection controlInpatientsKwaZulu-NatalCoughDrug resistanceHigh risk and rapid appearance of multidrug resistance during tuberculosis treatment in Moldova.
Jenkins HE, Crudu V, Soltan V, Ciobanu A, Domente L, Cohen T. High risk and rapid appearance of multidrug resistance during tuberculosis treatment in Moldova. European Respiratory Journal 2014, 43: 1132-41. PMID: 24558181, PMCID: PMC4005038, DOI: 10.1183/09031936.00203613.Peer-Reviewed Original ResearchConceptsMultidrug-resistant tuberculosisMDR-TB diagnosisMDR-TB casesTB treatmentFirst-line TB drugsAmbulatory TB treatmentMDR-TB riskDrug susceptibility testingNosocomial transmissionInitial diagnosisPercentage of individualsTB drugsTuberculosis treatmentEarly treatmentHigh riskSputum specimensSurveillance databasePrevious incarcerationDrug resistanceMultidrug resistanceDiagnosisTreatmentBaseline resistanceRapid appearanceRisk