2020
Smoking and HIV associated with subclinical tuberculosis: analysis of a population-based prevalence survey
Gunasekera K, Cohen T, Gao W, Ayles H, Godfrey-Faussett P, Claassens M. Smoking and HIV associated with subclinical tuberculosis: analysis of a population-based prevalence survey. The International Journal Of Tuberculosis And Lung Disease 2020, 24: 340-346. PMID: 32228765, DOI: 10.5588/ijtld.19.0387.Peer-Reviewed Original ResearchConceptsActive TBPrevalence surveyPopulation-based prevalence surveyCurrent tobacco smokingTypical symptomsHIV-positive statusTuberculosis prevalence surveyPrevalence survey dataSubclinical tuberculosisPositive TBCrude prevalenceTobacco smokingEpidemiological burdenPrevalent casesReduction TrialSubclinical TBMedical variablesSecondary analysisEstimate associationsSouth African communitySymptomsHIVSmokingTuberculosisDisease
2018
The impact of migration on tuberculosis in the United States
Menzies NA, Hill AN, Cohen T, Salomon JA. The impact of migration on tuberculosis in the United States. The International Journal Of Tuberculosis And Lung Disease 2018, 22: 1392-1403. PMID: 30606311, PMCID: PMC6353558, DOI: 10.5588/ijtld.17.0185.Peer-Reviewed Original ResearchConceptsTB casesTB burdenHigher tuberculosis ratesNew TB casesLow-incidence settingsEntry yearActive TBTB epidemiologyTB riskIncidence estimatesTuberculosis ratesLifetime casesUnited StatesRiskPopulation residentGreater exposureBurdenNative-born populationPopulationCountry of originTBYearsTuberculosisCasesInfectionProspects for Tuberculosis Elimination in the United States: Results of a Transmission Dynamic Model
Menzies NA, Cohen T, Hill AN, Yaesoubi R, Galer K, Wolf E, Marks SM, Salomon JA. Prospects for Tuberculosis Elimination in the United States: Results of a Transmission Dynamic Model. American Journal Of Epidemiology 2018, 187: 2011-2020. PMID: 29762657, PMCID: PMC6119121, DOI: 10.1093/aje/kwy094.Peer-Reviewed Original ResearchConceptsTB preventionTB eliminationLatent TB infection (LTBI) screeningTB case detectionHigh-risk populationImportant health benefitsTransmission dynamic modelIncident TBActive TBTuberculosis eliminationInfection testingTB controlTB incidenceEpidemiologic evidenceTB transmissionInfection screeningCase detectionTuberculosis trendsUS populationRisk determinantsHealth benefitsTreatment qualityUnited StatesTreatment activitiesTreatment
2016
Smear positivity in paediatric and adult tuberculosis: systematic review and meta-analysis
Kunkel A, Abel zur Wiesch P, Nathavitharana RR, Marx FM, Jenkins HE, Cohen T. Smear positivity in paediatric and adult tuberculosis: systematic review and meta-analysis. BMC Infectious Diseases 2016, 16: 282. PMID: 27296716, PMCID: PMC4906576, DOI: 10.1186/s12879-016-1617-9.Peer-Reviewed Original ResearchConceptsPercentage of childrenSmear positivityPooled percentageInverse variance heterogeneity modelPediatric TB casesSmear-positive TBNational TB ProgrammeBurden of TBGlobal Health databasesSputum smear microscopyActive TBAdult tuberculosisPositive TBTB casesTB programsAdult casesPROSPERO databaseSputum smearInclusion criteriaSmear microscopyHealth databasesSystematic reviewAdultsChildrenTuberculosis
2013
Community-Wide Isoniazid Preventive Therapy Drives Drug-Resistant Tuberculosis: A Model-Based Analysis
Mills HL, Cohen T, Colijn C. Community-Wide Isoniazid Preventive Therapy Drives Drug-Resistant Tuberculosis: A Model-Based Analysis. Science Translational Medicine 2013, 5: 180ra49. PMID: 23576815, PMCID: PMC3714172, DOI: 10.1126/scitranslmed.3005260.Peer-Reviewed Original ResearchConceptsDrug-resistant TBIPT interventionDrug-sensitive infectionsIsoniazid-resistant TBHIV/TBRisk of progressionHigh HIV prevalenceDrug-resistant diseaseIsoniazid-resistant Mycobacterium tuberculosisSymptom-free individualsSignificant elevated riskDrug-resistant strainsWorld Health OrganizationActive TBTB controlResistant tuberculosisHIV prevalenceTuberculosis controlIPT programElevated riskHost immunityMycobacterium tuberculosisHealth OrganizationSelective suppressionIntervention