2023
Refractory hepatic hydrothorax is associated with increased mortality with death occurring at lower MELD-Na compared to cirrhosis and refractory ascites
Chin A, Bastaich D, Dahman B, Kaplan D, Taddei T, John B. Refractory hepatic hydrothorax is associated with increased mortality with death occurring at lower MELD-Na compared to cirrhosis and refractory ascites. Hepatology 2023, 79: 844-856. PMID: 37625139, DOI: 10.1097/hep.0000000000000577.Peer-Reviewed Original ResearchLiver-related deathRefractory hepatic hydrothoraxRefractory ascitesMELD-NaHepatic hydrothoraxHigh riskRetrospective cohort studyRA overallSecond paracentesisCohort studyPrimary outcomeSerious complicationsEligibility criteriaCirrhosisInadequate evidenceParacentesisHydrothoraxAscitesDeathPatientsTransplantationRiskMortalityParticipantsComplications
2012
Beta‐blockers in patients with refractory ascites: To treat or not to treat. That is the question? But, what is the answer?
Guevara M, Groszmann R, Iwakiri Y, Taddei T. Beta‐blockers in patients with refractory ascites: To treat or not to treat. That is the question? But, what is the answer? Hepatology 2012, 56: 384-386. PMID: 22454325, DOI: 10.1002/hep.25724.Peer-Reviewed Original ResearchParacentesis-induced circulatory dysfunctionIncidence of paracentesis-induced circulatory dysfunctionPlasma renin concentrationRefractory ascitesBeta-blockersArterial pressureDevelopment of paracentesis-induced circulatory dysfunctionHeart rateTreated with beta-blockersChild-Pugh C.Intravenous albumin administrationBeta-blocker therapyEradication of varicesCross-over studyBaseline 1 weekEndoscopic eradicationAlbumin administrationBeta blockersMELD scoreRenin concentrationCirculatory dysfunctionAscitesCirrhosisParacentesisPatients