Toll-like receptor signaling in sepsis
Lakhani SA, Bogue CW. Toll-like receptor signaling in sepsis. Current Opinion In Pediatrics 2003, 15: 278-282. PMID: 12806257, DOI: 10.1097/00008480-200306000-00009.Peer-Reviewed Original ResearchMeSH KeywordsHumansLipopolysaccharidesMembrane GlycoproteinsReceptors, Cell SurfaceSepsisSignal TransductionToll-Like Receptor 4Toll-Like ReceptorsConceptsToll-like receptorsBacterial sepsisPediatric intensive care unitIntensive care unitPotential therapeutic approachPotential therapeutic strategySystemic inflammationCare unitMammalian immune systemInflammatory responseTLR signalingTherapeutic approachesTherapeutic strategiesDisease processSepsisImmune systemLPS responseBacterial lipopolysaccharideMajor causeMolecular patternsReceptorsOngoing evaluationMolecular biologyLipopolysaccharideMorbidity