2006
Anticoagulants or antiplatelet therapy for non‐rheumatic atrial fibrillation and flutter
Segal J, McNamara R, Miller M, Powe N, Goodman S, Robinson K, Bass E. Anticoagulants or antiplatelet therapy for non‐rheumatic atrial fibrillation and flutter. Cochrane Database Of Systematic Reviews 2006, 2010: cd001938. PMID: 17636690, PMCID: PMC10759270, DOI: 10.1002/14651858.cd001938.pub2.Peer-Reviewed Original ResearchConceptsAggregate odds ratioRisk of hemorrhageAtrial fibrillationStroke preventionMajor hemorrhageOdds ratioDose warfarinMajor bleedsModerate evidenceCochrane Collaboration's CENTRAL databaseNon-postoperative atrial fibrillationNon-rheumatic atrial fibrillationLow molecular weight heparinAdditional major bleedsLow-dose warfarinMore major bleedingMore major bleedsMore major hemorrhageRCTs of patientsPrimary stroke preventionLow-risk patientsRheumatic valvular diseasePrevention of thromboembolismRisk of strokeTrials of drugs
2001
Anticoagulants or antiplatelet therapy for non‐rheumatic atrial fibrillation and flutter
Segal J, McNamara R, Miller M, Powe N, Goodman S, Robinson K, Bass E. Anticoagulants or antiplatelet therapy for non‐rheumatic atrial fibrillation and flutter. 2001, cd001938. PMID: 11279741, DOI: 10.1002/14651858.cd001938.Peer-Reviewed Original ResearchConceptsRisk of hemorrhageAtrial fibrillationStroke preventionMajor hemorrhageDose warfarinMajor bleedsOdds ratioModerate evidenceCochrane Collaboration's CENTRAL databaseNon-postoperative atrial fibrillationNon-rheumatic atrial fibrillationLow molecular weight heparinAdditional major bleedsAggregate odds ratioLow-dose warfarinMore major bleedingMore major bleedsMore major hemorrhageRCTs of patientsPrimary stroke preventionLow-risk patientsRheumatic valvular diseasePrevention of thromboembolismRisk of strokeTrials of drugs
2000
Management of new onset atrial fibrillation.
McNamara R, Bass E, Miller M, Segal J, Goodman S, Kim N, Robinson K, Powe N. Management of new onset atrial fibrillation. Evidence Report Technology Assessment 2000, 1-7. PMID: 11471248, PMCID: PMC4781222.Peer-Reviewed Original ResearchAdultAge DistributionAgedAged, 80 and overAmbulatory CareAnti-Arrhythmia AgentsAnticoagulantsAspirinAtrial FibrillationClinical Trials as TopicComorbidityDecision Support TechniquesEchocardiographyElectric CountershockEvidence-Based MedicineFemaleHumansIncidenceMaleMiddle AgedPrognosisRisk FactorsSex DistributionSurvival RateThromboembolismTreatment OutcomePrevention of Thromboembolism in Atrial Fibrillation
Segal J, McNamara R, Miller M, Kim N, Goodman S, Powe N, Robinson K, Bass E, Center F. Prevention of Thromboembolism in Atrial Fibrillation. Journal Of General Internal Medicine 2000, 15: 56-67. PMID: 10632835, PMCID: PMC1495320, DOI: 10.1046/j.1525-1497.2000.04329.x.Peer-Reviewed Original ResearchConceptsAtrial fibrillationMajor bleedsStroke preventionMajor hemorrhageCochrane Collaboration's CENTRAL databaseAdditional major bleedsMore major bleedingMore major bleedsMore major hemorrhagePrimary stroke preventionPrevention of thromboembolismRisk of hemorrhageTrials of drugsCentral databaseMajor bleedingYounger patientsPrimary preventionMean agePatient riskBaseline riskStroke rateLower riskAspirinPatientsModerate evidence
1997
Echocardiographic identification of cardiovascular sources of emboli to guide clinical management of stroke: a cost-effectiveness analysis.
McNamara R, Lima J, Whelton P, Powe N. Echocardiographic identification of cardiovascular sources of emboli to guide clinical management of stroke: a cost-effectiveness analysis. Annals Of Internal Medicine 1997, 127: 775-87. PMID: 9382398, DOI: 10.7326/0003-4819-127-9-199711010-00001.Peer-Reviewed Original ResearchMeSH KeywordsAgedAnticoagulantsCardiovascular DiseasesCerebrovascular DisordersCohort StudiesCost-Benefit AnalysisDecision Support TechniquesEchocardiographyEchocardiography, TransesophagealHealth Care CostsHumansMarkov ChainsQuality-Adjusted Life YearsRecurrenceSensitivity and SpecificityThromboembolismConceptsTransesophageal echocardiographyAtrial thrombusRecurrent strokeTransthoracic echocardiographyCardiovascular sourcesNew-onset strokePotential cardiovascular sourcesRisks of anticoagulationEfficacy of anticoagulationNormal sinus rhythmQuality of lifeCost-effectiveness analysisIntracranial bleedingEchocardiographic identificationSinus rhythmAnticoagulation effectClinical managementCardiac problemsEchocardiographyAnticoagulationMedicare dataMortality ratePatientsHypothetical patientsClinical practice