2017
Impact of Enteroviral Polymerase Chain Reaction Testing on Length of Stay for Infants 60 Days Old or Younger
Aronson PL, Lyons TW, Cruz AT, Freedman SB, Okada PJ, Fleming AH, Arms JL, Thompson AD, Schmidt SM, Louie J, Alfonzo MJ, Monuteaux MC, Nigrovic LE, Group P, Alpern E, Balamuth F, Bradin S, Curtis S, Garro A, Grether-Jones K, Ishimine P, Kulik D, Mahajan P, Miller A, Mistry R, Pruitt C, Schnadower D, Shah S, Thomson J, Uspal N. Impact of Enteroviral Polymerase Chain Reaction Testing on Length of Stay for Infants 60 Days Old or Younger. The Journal Of Pediatrics 2017, 189: 169-174.e2. PMID: 28705656, PMCID: PMC5870831, DOI: 10.1016/j.jpeds.2017.06.021.Peer-Reviewed Original ResearchConceptsPCR testShorter LOSCentral nervous system infectionPolymerase chain reaction testingCerebrospinal fluid culturesNervous system infectionPlanned secondary analysisLarge multicenter cohortCerebrospinal fluid evaluationLength of stayPositive test resultsNegative test resultsDays of ageHospital lengthHospital LOSRetrospective cohortSystem infectionBacterial meningitisMulticenter cohortPatient ageFluid cultureHospital CenterPCR testingReaction testingInfants
2015
Association between Clinical Outcomes and Hospital Guidelines for Cerebrospinal Fluid Testing in Febrile Infants Aged 29-56 Days
Chua KP, Neuman MI, McWilliams JM, Aronson PL, Collaborative F, Thurm C, Williams D, Browning W, Nigrovic L, Alpern E, Tieder J, Feldman E, Shah S, Schondelmeyer A, Alessandrini E, McCulloh R, Myers A, Balamuth F, Hayes K. Association between Clinical Outcomes and Hospital Guidelines for Cerebrospinal Fluid Testing in Febrile Infants Aged 29-56 Days. The Journal Of Pediatrics 2015, 167: 1340-1346.e9. PMID: 26477870, PMCID: PMC5535778, DOI: 10.1016/j.jpeds.2015.09.021.Peer-Reviewed Original ResearchConceptsClinical practice guidelinesOlder febrile infantsFebrile infantsCerebrospinal fluid testingClinical outcomesCSF testingAdverse eventsFluid testingYoung febrile infantsCentral venous cathetersUS children's hospitalsSignificant differencesMedian annual household incomeRace/ethnicityAnnual household incomeHospital mortalityVenous cathetersBacterial meningitisMembrane oxygenationPrimary outcomeHospital guidelinesMechanical ventilationChildren's HospitalEmergency departmentPractice guidelinesAssociation of clinical practice guidelines with emergency department management of febrile infants ≤56 days of age
Aronson PL, Thurm C, Williams DJ, Nigrovic LE, Alpern ER, Tieder JS, Shah SS, McCulloh RJ, Balamuth F, Schondelmeyer AC, Alessandrini EA, Browning WL, Myers AL, Neuman MI, Collaborative F. Association of clinical practice guidelines with emergency department management of febrile infants ≤56 days of age. Journal Of Hospital Medicine 2015, 10: 358-365. PMID: 25684689, PMCID: PMC4456211, DOI: 10.1002/jhm.2329.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Bacterial AgentsBlood Chemical AnalysisCeftriaxoneCerebrospinal FluidCost ControlCross-Sectional StudiesEmergency Service, HospitalFeverGuideline AdherenceHealth Care SurveysHealth Information SystemsHospitals, PediatricHumansInfantInfant, NewbornPractice Guidelines as TopicRetrospective StudiesUnited StatesUrinalysisConceptsClinical practice guidelinesCeftriaxone useCPG recommendationsInfants 29CSF testingHealthcare costsED dischargeFebrile infantsPractice guidelinesInstitutional clinical practice guidelinePediatric Health Information SystemRetrospective cross-sectional studyCerebrospinal fluid testingEmergency department managementCross-sectional studyLower healthcare costsRate of urineDiagnosis of feverDays of ageED visitsPractice variationDepartment managementAge groupsHealth information systemsFluid testing