2016
Histological Disease Activity as a Predictor of Clinical Relapse Among Patients With Ulcerative Colitis: Systematic Review and Meta-Analysis
Park S, Abdi T, Gentry M, Laine L. Histological Disease Activity as a Predictor of Clinical Relapse Among Patients With Ulcerative Colitis: Systematic Review and Meta-Analysis. The American Journal Of Gastroenterology 2016, 111: 1692. PMID: 27725645, DOI: 10.1038/ajg.2016.418.Peer-Reviewed Original ResearchConceptsRelapse/exacerbationHistological remissionEndoscopic remissionClinical remissionHistological activityClinical outcomesUlcerative colitisHistological statusClinical relapseHistological featuresLamina propriaChronic inflammatory cell infiltrateAdditional prognostic utilityHistological disease activityProportion of patientsInflammatory bowel diseaseInflammatory cell infiltrateLack of blindingImproved clinical outcomesDifferent histological featuresSpecific histological featuresRandom-effects modelFixed-effects modelDisease activityUC patients
2010
Cytomegalovirus Infection in Patients with Active Inflammatory Bowel Disease
Kim JJ, Simpson N, Klipfel N, DeBose R, Barr N, Laine L. Cytomegalovirus Infection in Patients with Active Inflammatory Bowel Disease. Digestive Diseases And Sciences 2010, 55: 1059-1065. PMID: 20112061, DOI: 10.1007/s10620-010-1126-4.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseActive inflammatory bowel diseaseActive ulcerative colitisUC patientsIndex flareCMV infectionUlcerative colitisCrohn's diseaseCytomegalovirus infectionBowel diseasePrevalence of CMVCourse of diseaseAcute exacerbationIBD colitisUC flareCMV antigensConclusionsThe prevalenceIndex endoscopyMethodsConsecutive patientsClinical courseSevere morbidityClinical featuresImmunohistochemistry stainingGeneral populationPatients