1991
Identification and localization of a dogfish homolog of human cystic fibrosis transmembrane conductance regulator.
Marshall J, Martin K, Picciotto M, Hockfield S, Nairn A, Kaczmarek L. Identification and localization of a dogfish homolog of human cystic fibrosis transmembrane conductance regulator. Journal Of Biological Chemistry 1991, 266: 22749-22754. PMID: 1718999, DOI: 10.1016/s0021-9258(18)54631-7.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceCell MembraneCloning, MolecularCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorDNADogfishHumansImmunoenzyme TechniquesMembrane ProteinsMolecular Sequence DataMolecular WeightProtein KinasesRectumSebaceous GlandsSequence Homology, Nucleic AcidSubstrate SpecificityConceptsCystic fibrosis transmembrane conductance regulatorHuman cystic fibrosis transmembrane conductance regulatorFibrosis transmembrane conductance regulatorTransmembrane conductance regulatorDogfish proteinRectal glandConductance regulatorPutative substrate sitesCyclic AMP-dependent protein kinaseAMP-dependent protein kinaseMajor phosphorylation siteCyclic AMP-dependent protein phosphorylationApical plasma membraneAmino acid sequenceStudy of regulationPhosphorylation sitesProtein phosphorylationCDNA clonesProtein kinaseSimilar molecular massCFTR sequencePlasma membraneAcid sequenceImmunolocalization studiesMolecular mass
1982
Intracellular modulation of membrane channels by cyclic AMP-mediated protein phosphorylation in peptidergic neurons of Aplysia.
Strumwasser F, Kaczmarek L, Jennings K. Intracellular modulation of membrane channels by cyclic AMP-mediated protein phosphorylation in peptidergic neurons of Aplysia. The FASEB Journal 1982, 41: 2933-9. PMID: 6292000.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsProtein phosphorylationCyclic AMPPotassium channelsBag cell neuronsEgg-laying hormoneMembrane channelsIntracellular modulationPhosphorylationPeptidergic bag cell neuronsCell neuronsExact identityPeptidergic neuronsImportant componentControl eggsElectrical afterdischargeNeuroactive peptidesAMPEggsCorrelated behaviorNeuronsAplysiaPeptidesProtein phosphorylation during afterdischarge in peptidergic neurons of Aplysia
Jennings K, Kaczmarek L, Hewick R, Dreyer W, Strumwasser F. Protein phosphorylation during afterdischarge in peptidergic neurons of Aplysia. Journal Of Neuroscience 1982, 2: 158-168. PMID: 6278103, PMCID: PMC6564306, DOI: 10.1523/jneurosci.02-02-00158.1982.Peer-Reviewed Original Research
1980
Purification and primary structure of two neuroactive peptides that cause bag cell afterdischarge and egg-laying in Aplysia
Heller E, Kaczmarek L, Hunkapiller M, Hood L, Strumwasser F. Purification and primary structure of two neuroactive peptides that cause bag cell afterdischarge and egg-laying in Aplysia. Proceedings Of The National Academy Of Sciences Of The United States Of America 1980, 77: 2328-2332. PMID: 6929554, PMCID: PMC348708, DOI: 10.1073/pnas.77.4.2328.Peer-Reviewed Original ResearchConceptsBag cell neuronsEgg-laying hormoneCell neuronsNeuroactive peptidesBag cell afterdischargePeptide BPleuroabdominal connectivesAbdominal ganglionRecipient animalsNeuronal receptorsHead gangliaVitro recordingsReproductive tractBag cellsGangliaAtrial glandNeuronsAtrial gland peptidesHormoneGlandGland peptideAgarose gel filtrationPeptide AAplysiaPro-Phe