2008
Repetitive Firing Triggers Clustering of Kv2.1 Potassium Channels in Aplysia Neurons*
Zhang Y, McKay SE, Bewley B, Kaczmarek LK. Repetitive Firing Triggers Clustering of Kv2.1 Potassium Channels in Aplysia Neurons*. Journal Of Biological Chemistry 2008, 283: 10632-10641. PMID: 18276591, DOI: 10.1074/jbc.m800253200.Peer-Reviewed Original ResearchConceptsBag cell neuronsKv2.1 channelsPotassium channelsPlasma membraneC-terminusKv2.1 clustersKv2.1 potassium channelCell neuronsMammalian neuronsReproductive behaviorRectifier potassium channelFrequency-dependent broadeningRapid redistributionAplysia neuronsClamp recordingsAcid peptidePartial inactivationRing-like clustersPhysiological changesKv2.1Neuronal excitabilityCentral nervous systemAction potentialsGenesNervous system
1996
Inhibition by Nystatin of Kv1.3 Channels Expressed in Chinese Hamster Ovary Cells
HAHN S, WANG L, KACZMAREK L. Inhibition by Nystatin of Kv1.3 Channels Expressed in Chinese Hamster Ovary Cells. Neuropharmacology 1996, 35: 895-901. PMID: 8938720, DOI: 10.1016/0028-3908(96)00094-9.Peer-Reviewed Original ResearchConceptsKv1.3 currentsEffect of nystatinPerforated patch recordingsChinese hamster ovary cellsPatch-clamp techniqueWhole-cell configurationConcentration-dependent reductionHamster ovary cellsRectifier potassium channelHalf-maximal inhibitionPotassium channel Kv1.3Patch recordingsMaximal inhibitionAmphotericin BOvary cellsKv1.3 channelsPotassium channelsTetraethylammoniumChannel Kv1.3Intracellular solutionInhibitionRapid blockNystatinDrugsApparent inactivation
1990
Cloning and expression of cDNA and genomic clones encoding three delayed rectifier potassium channels in rat brain
Swanson R, Marshall J, Smith J, Williams J, Boyle M, Folander K, Luneau C, Antanavage J, Oliva C, Buhrow S, Bennet C, Stein R, Kaczmarek L. Cloning and expression of cDNA and genomic clones encoding three delayed rectifier potassium channels in rat brain. Neuron 1990, 4: 929-939. PMID: 2361015, DOI: 10.1016/0896-6273(90)90146-7.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceBrainCloning, MolecularDNAFemaleMembrane ProteinsMolecular Sequence DataOligonucleotide ProbesOocytesOrgan SpecificityPotassium ChannelsProtein BiosynthesisRatsRats, Inbred StrainsRestriction MappingRNA, MessengerSequence Homology, Nucleic AcidTranscription, GeneticXenopusConceptsRectifier potassium channelRat brain cDNARat brainPotassium channelsCardiac tissueMarked increaseBrainXenopus oocytesKv1Brain cDNAKv3MRNATissueKv2