2015
Learning and Memory
Levitan I, Kaczmarek L. Learning and Memory. 2015, 489-528. DOI: 10.1093/med/9780199773893.003.0019.ChaptersSimple nervous systemLong-term depressionLong-term potentiationMolecular mechanismsEnormous diversityNormal developmentCellular mechanismsNervous systemPresynaptic terminalsMost nervous systemsCyclic AMPSynaptic scalingPathwayMemory formationPlasticityPostsynaptic receptorsSynaptic taggingSynaptic connectionsLong-term phaseReduced preparationsDiversitySpike-timing dependent plasticityMechanismSynapseReceptors
1990
Cyclic AMP regulates processing of neuropeptide precursor in bag cell neurons ofAplysia
Azhderian E, Kaczmarek L. Cyclic AMP regulates processing of neuropeptide precursor in bag cell neurons ofAplysia. Journal Of Molecular Neuroscience 1990, 2: 61-70. PMID: 1964064, DOI: 10.1007/bf02876912.Peer-Reviewed Original ResearchConceptsBag cell neuronsEgg-laying hormoneCell neuronsCAMP levelsPresence of tetrodotoxinBag cell clustersAdenylate cyclase activator forskolinELH prohormoneCyclase activator forskolinElevation of cAMPMembrane-permeant cAMP analogAbdominal ganglionControl clustersPermeant cAMP analogueAction potentialsNeuroactive peptidesTreatment of cellsProtein synthesis inhibitor anisomycinActivator forskolinNeuronsProhormoneAfterdischargesCyclic AMPTetrodotoxinComparative peptide mapping
1982
Intracellular modulation of membrane channels by cyclic AMP-mediated protein phosphorylation in peptidergic neurons of Aplysia.
Strumwasser F, Kaczmarek L, Jennings K. Intracellular modulation of membrane channels by cyclic AMP-mediated protein phosphorylation in peptidergic neurons of Aplysia. The FASEB Journal 1982, 41: 2933-9. PMID: 6292000.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsProtein phosphorylationCyclic AMPPotassium channelsBag cell neuronsEgg-laying hormoneMembrane channelsIntracellular modulationPhosphorylationPeptidergic bag cell neuronsCell neuronsExact identityPeptidergic neuronsImportant componentControl eggsElectrical afterdischargeNeuroactive peptidesAMPEggsCorrelated behaviorNeuronsAplysiaPeptides
1978
Neurotransmitter modulation, phosphodiesterase inhibitor effects, and cyclic AMP correlates of afterdischarge in peptidergic neurites
Kaczmarek L, Jennings K, Strumwasser F. Neurotransmitter modulation, phosphodiesterase inhibitor effects, and cyclic AMP correlates of afterdischarge in peptidergic neurites. Proceedings Of The National Academy Of Sciences Of The United States Of America 1978, 75: 5200-5204. PMID: 217016, PMCID: PMC336293, DOI: 10.1073/pnas.75.10.5200.Peer-Reviewed Original Research