2001
Surgical conservation planning after neoadjuvant chemotherapy for stage II and operable stage III breast carcinoma
Kuerer H, Singletary S, Buzdar A, Ames F, Valero V, Buchholz T, Ross M, Pusztai L, Hortobagyi G, Hunt K. Surgical conservation planning after neoadjuvant chemotherapy for stage II and operable stage III breast carcinoma. The American Journal Of Surgery 2001, 182: 601-608. PMID: 11839324, DOI: 10.1016/s0002-9610(01)00793-0.Peer-Reviewed Original ResearchConceptsLocal-regional recurrence rateOperable breast cancerPrimary tumorBreast cancerTumor downstagingNeoadjuvant chemotherapyResidual carcinomaRecurrence rateStage III breast carcinomaStage IIComplete clinical responseCycles of chemotherapyMedian tumor sizeAxillary node dissectionBreast conservation surgeryNode dissectionClinical responseProspective trialSurgical resectionPalpable massSegmental resectionAdequate resectionPathologic examinationTumor sizeLarge tumors
1999
Relapse after complete response to anthracycline‐based combination chemotherapy in metastatic breast cancer
Pusztai L, Asmar L, Smith T, Hortobagyi G. Relapse after complete response to anthracycline‐based combination chemotherapy in metastatic breast cancer. Breast Cancer Research And Treatment 1999, 55: 1-8. PMID: 10472774, DOI: 10.1023/a:1006161906667.Peer-Reviewed Original ResearchConceptsAnthracycline-based combination chemotherapyComplete clinical responseDisease-free intervalMetastatic breast cancerInitial disease-free intervalSecond relapseFirst relapseCombination chemotherapyCR durationMedian survivalBreast cancerShorter CR durationSite of recurrenceLength of survivalMore frequent recurrenceClinical characteristicsClinical responseFirst recurrenceMetastatic diseaseVisceral sitesComplete responseClinical featuresMetastatic sitesSubsequent therapySecond recurrence