1995
Vigabatrin: effect on brain GABA levels measured by nuclear magnetic resonance spectroscopy
Mattson R, Petroff O, Rothman D, Behar K. Vigabatrin: effect on brain GABA levels measured by nuclear magnetic resonance spectroscopy. Acta Neurologica Scandinavica. Supplementum 1995, 92: 27-30. PMID: 7495186, DOI: 10.1111/j.1600-0404.1995.tb00496.x.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsBrain GABA levelsGABA levelsBrain concentrationsNerve terminalsAdministration of vigabatrinClear dose-response relationshipLevels of GABAPartial epileptic seizuresAnti-epilepsy drugsPresynaptic nerve terminalsDose-response relationshipConcentration of GABASecondary generalizationClinical effectsClinical outcomesVigabatrin administrationClinical trialsPatient responseClinical studiesSynaptic transmissionBaseline valuesOptimal doseVigabatrin levelsVigabatrinEpileptic seizures
1989
In Vivo NMR Spectroscopy Studies of Cerebral Metabolism in Rats after Portal-Caval Shunting.
Fitzpatrick S, Behar K, Shulman R. In Vivo NMR Spectroscopy Studies of Cerebral Metabolism in Rats after Portal-Caval Shunting. Experimental Biology And Medicine 1989, 177-187. DOI: 10.1007/978-1-4612-4506-3_12.ChaptersPortal-caval shuntingInsufficient liver functionCerebral metabolismHepatic encephalopathyLiver functionVivo NMR spectroscopy studiesNeurological impairmentClinical studiesClinical conditionsSystemic circulationAnimal modeBrain tissueBloodBiochemical mechanismsEncephalopathyPathogenesisShuntingRatsShuntLiverImpairment