2007
On the Need to Compensate for Edema-Induced Dose Reductions in Preplanned 131Cs Prostate Brachytherapy
Chen ZJ, Deng J, Roberts K, Nath R. On the Need to Compensate for Edema-Induced Dose Reductions in Preplanned 131Cs Prostate Brachytherapy. International Journal Of Radiation Oncology • Biology • Physics 2007, 70: 303-310. PMID: 17980500, PMCID: PMC2289996, DOI: 10.1016/j.ijrobp.2007.09.007.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsBrachytherapyCesium RadioisotopesDisease-Free SurvivalDose-Response Relationship, RadiationEdemaHumansMaleProstatic DiseasesProstatic NeoplasmsRadiotherapy DosageRelative Biological EffectivenessTime FactorsConceptsDose reductionProstate brachytherapyDose compensationLarge edemaBiochemical recurrence-free survivalRecurrence-free survivalSignificant dose reductionEffects of edemaSublethal damage repairAdditional irradiationPrescription doseProstate cancerIndividual patientsEdemaEdema evolutionPrescribed doseProstate edemaEffective doseRadiobiologic effectsBrachytherapyDoseProstate implantsDose responseImplants
2004
Optimization of dose distributions for bifurcated coronary vessels treated with catheter‐based photon and beta emitters using the simulated annealing algorithm
Yue N, Roberts KB, Son H, Khosravi S, Pfau SE, Nath R. Optimization of dose distributions for bifurcated coronary vessels treated with catheter‐based photon and beta emitters using the simulated annealing algorithm. Medical Physics 2004, 31: 2610-2622. PMID: 15487744, DOI: 10.1118/1.1783533.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsAnimalsBeta ParticlesBlood Vessel ProsthesisBrachytherapyCatheterizationCatheters, IndwellingComputer SimulationCoronary RestenosisHumansModels, CardiovascularPhotonsRadiometryRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRelative Biological EffectivenessReproducibility of ResultsSensitivity and SpecificityConceptsTreatment schemeCatheter-based delivery systemBetter dose distributionDose distributionDwell positionsPrescription doseCoronary vesselsBranch vesselsBranch treatmentBifurcation angleSatisfactory dose distributionMultiple dwell positionsVesselsOverdosingDelivery systemGeometry of bifurcations
1999
Long‐term complications with prostate implants: Iodine‐125 vs. palladium‐103
Peschel R, Chen Z, Roberts K, Nath R. Long‐term complications with prostate implants: Iodine‐125 vs. palladium‐103. International Journal Of Cancer 1999, 7: 278-288. PMID: 10580897, DOI: 10.1002/(sici)1520-6823(1999)7:5<278::aid-roi3>3.0.co;2-3.Peer-Reviewed Original ResearchMeSH KeywordsActuarial AnalysisBrachytherapyCell DeathFollow-Up StudiesForecastingHumansIodine RadioisotopesLongitudinal StudiesMaleModels, BiologicalNeoplasm StagingPalladiumProbabilityProstatic NeoplasmsRadioisotopesRadiopharmaceuticalsRadiotherapy DosageRelative Biological EffectivenessRetrospective StudiesTreatment OutcomeConceptsLong-term complicationsMinimum tumor dosesComplication ratePd-103Lower overall complication ratePalladium-103Long-term complication rateIodine-125Overall complication rateHigh complication rateProstate cancer patientsProstate implantsActuarial probabilityGrade IIILog10 cell killCancer patientsVs. 6Tumor dosesClinical practiceCell killProstate cancer brachytherapyEffective doseNormal tissuesPatientsTissue beds