2009
Prospective Evaluation of Fetuses With Autoimmune-Associated Congenital Heart Block Followed in the PR Interval and Dexamethasone Evaluation (PRIDE) Study
Friedman DM, Kim MY, Copel JA, Llanos C, Davis C, Buyon JP. Prospective Evaluation of Fetuses With Autoimmune-Associated Congenital Heart Block Followed in the PR Interval and Dexamethasone Evaluation (PRIDE) Study. The American Journal Of Cardiology 2009, 103: 1102-1106. PMID: 19361597, PMCID: PMC2730772, DOI: 10.1016/j.amjcard.2008.12.027.Peer-Reviewed Original ResearchConceptsThird-degree blockSecond-degree blockCongenital heart blockFirst-degree blockDEX groupHeart blockAutoimmune-Associated Congenital Heart BlockEfficacy of dexamethasoneSteroid side effectsNormal sinus rhythmMedian ventricular ratesCardiac dysfunctionGestational ageVentricular rateNonrandomized studyProspective evaluationSinus rhythmGrowth restrictionPR intervalPacemaker useRare caseTherapeutic benefitSide effectsBirth ageDexamethasone
2002
Spectrum and progression of conduction abnormalities in infants born to mothers with anti-SSA/Ro-SSB/La antibodies
Askanase A, Friedman D, Copel J, Dische M, Dubin A, Starc T, Katholi M, Buyon J. Spectrum and progression of conduction abnormalities in infants born to mothers with anti-SSA/Ro-SSB/La antibodies. Lupus 2002, 11: 145-151. PMID: 11999879, DOI: 10.1191/0961203302lu173oa.Peer-Reviewed Original ResearchConceptsSSA/Ro-SSB/La antibodiesThird-degree blockCongenital heart blockLa antibodiesSecond-degree blockConduction abnormalitiesDegree blockNeonatal lupusHeart blockAV blockAtrial rateAV nodeAntibody-mediated inflammationMean atrial rateAdvanced AV blockTime of surgeryFirst-degree blockSpectrum of arrhythmiasNormal sinus rhythmAge 10 yearsIncomplete AV blockCardiac manifestationsNodal involvementSinus bradycardiaSubsequent fibrosis
2001
Anti‐Ro/SSA antibodies and congenital heart block: Necessary but not sufficient
Buyon J, Kim M, Copel J, Friedman D. Anti‐Ro/SSA antibodies and congenital heart block: Necessary but not sufficient. Arthritis & Rheumatism 2001, 44: 1723-1727. PMID: 11508420, DOI: 10.1002/1529-0131(200108)44:8<1723::aid-art305>3.0.co;2-0.Peer-Reviewed Original Research
1998
Autoimmune-Associated Congenital Heart Block: Demographics, Mortality, Morbidity and Recurrence Rates Obtained From a National Neonatal Lupus Registry
Buyon J, Hiebert R, Copel J, Craft J, Friedman D, Katholi M, Lee L, Provost T, Reichlin M, Rider L, Rupel A, Saleeb S, Weston W, Skovron M. Autoimmune-Associated Congenital Heart Block: Demographics, Mortality, Morbidity and Recurrence Rates Obtained From a National Neonatal Lupus Registry. Journal Of The American College Of Cardiology 1998, 31: 1658-1666. PMID: 9626848, DOI: 10.1016/s0735-1097(98)00161-2.Peer-Reviewed Original ResearchConceptsCongenital heart blockNeonatal lupus syndromeSSA/RoWeeks of gestationRecurrence rateLa antibodiesSubsequent pregnancySSA/Ro-SSB/La antibodiesAutoantibody-associated congenital heart blockDevelopment of CHBAnti-SSB/La antibodiesAnti-SSA/RoIsolated congenital heart blockClose echocardiographic monitoringLate second trimesterDays of lifeSSB/LaSufficient medical recordsMajor structural abnormalitiesMaternal autoantibodiesLupus syndromeNeonatal lupusEchocardiographic monitoringLupus RegistryHeart block