1996
Nicked free β-subunit of human chorionic gonadotropin: A potential new marker for Down syndrome screening
Rotmensch S, Liberati M, Kardana A, Copel J, Ben-Rafael Z, Cole L. Nicked free β-subunit of human chorionic gonadotropin: A potential new marker for Down syndrome screening. American Journal Of Obstetrics And Gynecology 1996, 174: 609-611. PMID: 8623792, DOI: 10.1016/s0002-9378(96)70435-0.Peer-Reviewed Original ResearchConceptsHuman chorionic gonadotropinDown syndrome screeningChorionic gonadotropinSyndrome pregnanciesSyndrome screeningFree beta subunitMaternal serum levelsDown syndrome pregnanciesPotential new markerFree β-subunitSerum levelsNormal controlsSensitive markerImmunoenzymometric assaySerum specimensDown syndromeGonadotropinMean levelsNew markersPreliminary dataMedianPregnancyCase levelMarkersΒ-subunit
1992
Fetuses with Down syndrome have disproportionately shortened frontal lobe dimensions on ultrasonographic examination
Bahado-Singh R, Wyse L, Dorr M, Copel J, O'Connor T, Hobbins J. Fetuses with Down syndrome have disproportionately shortened frontal lobe dimensions on ultrasonographic examination. American Journal Of Obstetrics And Gynecology 1992, 167: 1009-1014. PMID: 1415385, DOI: 10.1016/s0002-9378(12)80029-9.Peer-Reviewed Original ResearchConceptsDown syndrome fetusesSyndrome fetusesFrontothalamic distanceDown syndromePositive predictive valueWeeks' gestationGestational ageNormal medianPosterior thalamusUltrasonographic examinationGroup 52Normal fetusesFrontal lobePredictive valueInner tableFetusesFrontal boneMedianGestationMean valueSyndrome