2019
Fetal Myocardial Function as Assessed by N-Terminal Fragment Brain Natriuretic Protein in Premature Fetuses Exposed to Intra-amniotic Inflammation
Irani RA, Buhimschi CS, Cross SN, Zhao G, Copel JA, Bhandari V, Buhimschi IA, Bahtiyar MO. Fetal Myocardial Function as Assessed by N-Terminal Fragment Brain Natriuretic Protein in Premature Fetuses Exposed to Intra-amniotic Inflammation. American Journal Of Perinatology 2019, 37: 745-753. PMID: 31121635, DOI: 10.1055/s-0039-1688909.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmniocentesisAmniotic FluidBiomarkersChorioamnionitisEchocardiography, DopplerFemaleFetal BloodFetal HeartHumansInfant, NewbornInfant, PrematureInflammationInterleukin-6MaleMass SpectrometryNatriuretic Peptide, BrainPeptide FragmentsPlacentaPregnancyPremature BirthVentricular Function, LeftConceptsIntra-amniotic infection/inflammationBrain natriuretic proteinAmniotic fluidNT-proBNPTei indexNatriuretic proteinVentricular functionFetal exposureCord bloodCord IL-6Intra-amniotic inflammationFetal myocardial functionInfection/inflammationBlood NT-proBNPFetal heart functionNT-proBNP immunoassaysEnzyme-linked immunosorbentGestational agePremature fetusesFetal echocardiogramIL-6Circulatory levelsMyocardial functionHeart functionFetuses
1998
Elevated amniotic fluid nitric oxide metabolites and interleukin-6 in intra-amniotic infection.
Hsu C, Meaddough E, Hong S, Aversa K, Lu L, Copel J. Elevated amniotic fluid nitric oxide metabolites and interleukin-6 in intra-amniotic infection. Reproductive Sciences 1998, 5: 21-4. PMID: 9501294, DOI: 10.1016/s1071-5576(97)00099-3.Peer-Reviewed Original ResearchConceptsAmniotic fluid nitric oxide metabolitesIntra-amniotic infectionNitric oxide metabolitesLeukocyte esterase activityIL-6Oxide metabolitesLeukocyte countInterleukin-6Glucose levelsRank correlation testAmniotic fluid creatinine levelsAmniotic fluid glucose levelAmniotic fluid IL-6Positive amniotic fluid cultureGram stainIL-6 levelsInterleukin-6 concentrationsIL-6 concentrationsAmniotic fluid leukocyte countsUseful clinical markerMann-Whitney U testEnzyme-linked immunosorbentAmniotic fluid cultureCreatinine levelsGestational ageElevated Amniotic Fluid Nitrix Oxide Metabolites and Interleukin-6 in Intra-amniotic Infection
Hsu C, Meaddough E, Hong S, Aversa K, Lu L, Copel J. Elevated Amniotic Fluid Nitrix Oxide Metabolites and Interleukin-6 in Intra-amniotic Infection. Reproductive Sciences 1998, 5: 21-24. DOI: 10.1177/107155769800500105.Peer-Reviewed Original ResearchAmniotic fluid nitric oxide metabolitesIntra-amniotic infectionNitric oxide metabolitesLeukocyte esterase activityIL-6Oxide metabolitesLeukocyte countInterleukin-6Glucose levelsRank correlation testAmniotic fluid creatinine levelsAmniotic fluid glucose levelAmniotic fluid IL-6Positive amniotic fluid cultureGram stainIL-6 concentrationsIL-6 levelsInterleukin-6 concentrationsAmniotic fluid leukocyte countsUseful clinical markerMann-Whitney U testEnzyme-linked immunosorbentAmniotic fluid cultureCreatinine levelsGestational age
1995
Thrombomodulin levels in preeclampsia, gestational hypertension, and chronic hypertension.
Hsu C, Copel J, Hong S, Chan D. Thrombomodulin levels in preeclampsia, gestational hypertension, and chronic hypertension. Obstetrics And Gynecology 1995, 86: 897-9. PMID: 7501335, DOI: 10.1016/0029-7844(95)00326-m.Peer-Reviewed Original ResearchConceptsChronic hypertensionGestational hypertensionThrombomodulin levelsSerum thrombomodulin levelsSoluble thrombomodulin antigenNormotensive control groupTwo-site enzyme-linked immunosorbentLevels of thrombomodulinNormotensive pregnant womenEnzyme-linked immunosorbentACOG criteriaHypertensive disordersSerum levelsThird trimesterNormotensive controlsPregnant womenHypertensionPreeclampsiaThrombomodulin antigenControl groupThrombomodulinWomenSignificant differencesMeaningful markersTrimester
1993
Identification of mothers at risk for congenital heart block and other neonatal lupus syndromes in their children. comparison of enzyme‐linked immunosorbent assay and immunoblot for measurement of anti–ss‐a/ro and anti–ss‐b/la antibodies
Buyon J, Winchester R, Slade S, Arnett F, Copel J, Friedman D, Lockshin M. Identification of mothers at risk for congenital heart block and other neonatal lupus syndromes in their children. comparison of enzyme‐linked immunosorbent assay and immunoblot for measurement of anti–ss‐a/ro and anti–ss‐b/la antibodies. Arthritis & Rheumatism 1993, 36: 1263-1273. PMID: 8216420, DOI: 10.1002/art.1780360911.Peer-Reviewed Original ResearchConceptsEnzyme-linked immunosorbent assayNeonatal lupus syndromeNeonatal lupusCongenital heart blockHeart blockSDS-immunoblotRo antibodiesHealthy infantsMothers of childrenLupus syndromeLa antibodiesFetal deathAutoimmune diseasesRo antigenRo responseDetectable cardiac involvementFetal death groupSystemic lupus erythematosusSpecific antibody profileMothers of infantsRelated autoimmune diseasesIdentification of mothersEnzyme-linked immunosorbentFine specificity patternsGroups of mothers