2016
Clinical Heterogeneity Arising from Categorical and Dimensional Features of the Neurobiology of Psychiatric Diagnoses: Insights from Neuroimaging and Computational Neuroscience
Krystal J, Anticevic A, Murray J, Glahn D, Driesen N, Yang G, Wang X. Clinical Heterogeneity Arising from Categorical and Dimensional Features of the Neurobiology of Psychiatric Diagnoses: Insights from Neuroimaging and Computational Neuroscience. 2016, 293-316. DOI: 10.7551/mitpress/10936.003.0023.Peer-Reviewed Original ResearchPsychiatric disordersMechanisms of psychiatric disordersModel psychiatric disordersPsychiatric nosologyPsychological assessmentPsychiatric diagnosingModern psychiatryPsychiatric issuesNeurobiologyPsychiatristsNeurological analysisPsychiatryDisordersComputational neuroscienceClinical heterogeneityNeuroimagingNosologyNeuroscienceNeuroscientistsComputational neuroscientistsCategorizationBiological Psychiatry and Biological Psychiatry: Cognitive Neuroscience and Neuroimaging Adopt Neuroscience-Based Nomenclature
Krystal JH, Abi-Dargham A, Barch DM, Bullmore ET, Carter CS, Geschwind DH, Harrison PJ, Nestler EJ, Stein MB. Biological Psychiatry and Biological Psychiatry: Cognitive Neuroscience and Neuroimaging Adopt Neuroscience-Based Nomenclature. Biological Psychiatry 2016, 80: 2-3. PMID: 27312230, DOI: 10.1016/j.biopsych.2016.03.2103.Peer-Reviewed Original ResearchBiological Psychiatry and Biological Psychiatry: Cognitive Neuroscience and Neuroimaging Adopt Neuroscience-Based Nomenclature
Krystal JH, Abi-Dargham A, Barch DM, Bullmore ET, Carter CS, Geschwind DH, Harrison PJ, Nestler EJ, Stein MB. Biological Psychiatry and Biological Psychiatry: Cognitive Neuroscience and Neuroimaging Adopt Neuroscience-Based Nomenclature. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2016, 1: 300-301. PMID: 29560862, DOI: 10.1016/j.bpsc.2016.03.007.Peer-Reviewed Original Research
2015
Integrating Acquired Preparedness and Dual Process Models of Risk for Heavy Drinking and Related Problems
Corbin WR, Papova A, Morean ME, O’Malley S, Krishnan-Sarin S, Abi-Dargham A, Anticevic A, Pearlson G, Petrakis I, Pittman BP, Krystal JH. Integrating Acquired Preparedness and Dual Process Models of Risk for Heavy Drinking and Related Problems. Psychology Of Addictive Behaviors 2015, 29: 864-874. PMID: 26348221, PMCID: PMC6223629, DOI: 10.1037/adb0000093.Peer-Reviewed Original ResearchConceptsDual-process modelImpulsive sensationExpectancy challengeDrinking outcomesStronger positive expectanciesAlcohol useIndirect effectsHeavy drinkingExplicit measuresPositive expectanciesAlcohol expectanciesPreparedness modelImplicit influencePersonality traitsNondependent drinkersBehavioral controlTranslational neuroscienceProcess modelAlcohol dependenceHigh levelsExpectancyDrinkingRelated problemsSensationNeuroscience
2013
Translational cognitive neuroscience of schizophrenia: bridging neurocognitive and computational approaches toward understanding cognitive deficits
Anticevic A, Krystal J, Barch D. Translational cognitive neuroscience of schizophrenia: bridging neurocognitive and computational approaches toward understanding cognitive deficits. 2013, 193-230. DOI: 10.1017/cbo9781139003872.013.Peer-Reviewed Original ResearchCognitive deficitsCognitive neuroscienceCourse of impairmentSevere mental illnessDeficitsSchizophreniaMental illnessPharmacological techniquesBiological contributionPrecise mechanismNeuroscienceIllnessLittle disputeRelated featuresStyleFunctional implicationsImpairmentManagement optionsImplicationsDisabilityPatientsSymptomsCliniciansDisease
2012
The role of default network deactivation in cognition and disease
Anticevic A, Cole MW, Murray JD, Corlett PR, Wang XJ, Krystal JH. The role of default network deactivation in cognition and disease. Trends In Cognitive Sciences 2012, 16: 584-592. PMID: 23142417, PMCID: PMC3501603, DOI: 10.1016/j.tics.2012.10.008.Peer-Reviewed Original ResearchConceptsDMN suppressionDefault network deactivationGoal-directed cognitionSpecific behavioral tasksDefault mode networkCognitive neurosciencePharmacological neuroimagingSuppression deficitsBehavioral tasksFocused attentionClinical neuroscienceTheoretical neuroscienceBrain regionsNeuroscienceCognitionSevere mental illnessMental illnessConsiderable bodyNeuroimagingTaskDeficitsDMNExternal environmentMindDisease
2011
Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia II: Developing Imaging Biomarkers to Enhance Treatment Development for Schizophrenia and Related Disorders
Carter CS, Barch DM, Bullmore E, Breiling J, Buchanan RW, Butler P, Cohen JD, Geyer M, Gollub R, Green MF, Jaeger J, Krystal JH, Moore H, Nuechterlein K, Robbins T, Silverstein S, Smith EE, Strauss M, Wykes T. Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia II: Developing Imaging Biomarkers to Enhance Treatment Development for Schizophrenia and Related Disorders. Biological Psychiatry 2011, 70: 7-12. PMID: 21529781, PMCID: PMC3116022, DOI: 10.1016/j.biopsych.2011.01.041.Peer-Reviewed Original ResearchConceptsCognitive Neuroscience Treatment ResearchTreatment researchCognitive neuroscienceTreatment developmentFunctional magnetic resonance imagingSchizophrenia (MATRICS) initiativeSchizophrenia IIPotential confoundsImpaired cognitionCognitionNeural systemsNeural activityPsychometric propertiesMental healthBrain functionTranscranial magnetic simulationNeuroscienceTreatment effectsSchizophreniaMulticenter phase IITranslational researchImproved animal modelsPragmatic issuesBiological psychiatryMagnetic resonance imaging
2008
Selecting Paradigms From Cognitive Neuroscience for Translation into Use in Clinical Trials: Proceedings of the Third CNTRICS Meeting
Barch DM, Carter CS, Arnsten A, Buchanan RW, Cohen JD, Geyer M, Green MF, Krystal JH, Nuechterlein K, Robbins T, Silverstein S, Smith EE, Strauss M, Wykes T, Heinssen R. Selecting Paradigms From Cognitive Neuroscience for Translation into Use in Clinical Trials: Proceedings of the Third CNTRICS Meeting. Schizophrenia Bulletin 2008, 35: 109-114. PMID: 19023126, PMCID: PMC2643950, DOI: 10.1093/schbul/sbn163.Peer-Reviewed Original ResearchConceptsFirst CNTRICS meetingCognitive neuroscienceCognitive Neuroscience Treatment ResearchPromising taskSchizophrenia (MATRICS) initiativeTreatment researchBroad domainsTaskSuch paradigmsNeuroscienceSpecific paradigmSpecific tasksRelevant paradigmConstructsParadigmLine surveyCognitionSpecial issueGoalNominationsDomainResearchInformationArticleTrials